Sagenit
Sagenit: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Sagenit
ATX code: G02CX
Active ingredient: mesodiethylethylendibenzene sulfonate dipotassium dihydrate (sygetin) [Mesodiethylethylendibenzosulfonate dipotassium dehydrate (Sigetin)]
Producer: Nizhny Novgorod chemical and pharmaceutical plant "NIZHFARM", JSC (Russia)
Description and photo update: 2019-20-08
Prices in pharmacies: from 697 rubles.
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Sagenit is an anti-climacteric agent.
Release form and composition
Dosage forms:
- tablets: flat-cylindrical, almost white or white (10 pcs. in a blister strip, in a cardboard box 1 or 3 packs);
- capsules: No. 1, hard gelatinous, with a white body and a green lid; the contents of the capsules are a mass of white or almost white color (10 pcs. in a blister strip, in a cardboard box 1 or 3 packs).
1 tablet contains:
- active ingredient: sygetin (mesodiethylethylenedibenzenesulfonate dipotassium dihydrate) - 100 mg;
- excipients: stearic acid, starch, microcrystalline cellulose.
1 capsule contains:
- active ingredient: sygetin (mesodiethylethylenedibenzenesulfonate dipotassium dihydrate) - 100 mg;
- excipients: stearic acid, potato starch, sucrose (sugar);
- capsule shell: indigo carmine, titanium dioxide, yellow quinoline dye, gelatin.
Pharmacological properties
Pharmacodynamics
Mesodiethylethylenedibenzenesulfonate promotes the implementation of negative and positive feedback in the hypothalamic-pituitary-ovarian system, stabilizes the hypothalamic center and gonadotropic function of the pituitary gland, while not exerting an estrogenic effect on target organs. The drug enhances uterine contractions, activates placental blood flow, increases the level of beta-lipoproteins in the blood and glucose utilization, improves tissue sensitivity to the action of insulin.
Indications for use
According to the instructions, Sagenit is used for climacteric syndrome, the characteristic features of which are: increased sweating, "hot flashes", degenerative changes in the skin and mucous membranes (thinning of the skin, brittle nails, the formation of wrinkles, dystrophy of the urinary tract mucosa), sleep disturbance, depression, irritability, forgetfulness.
Contraindications
- metrorrhagia;
- the period of pregnancy and breastfeeding;
- individual intolerance to the components of the drug.
Sagenit should be taken with caution in women with impaired liver function, renal failure, hyperlipoproteinemia.
Instructions for use of Sagenit: method and dosage
Pills
It is taken orally, regardless of the meal.
Recommended dosage: 1 tablet per day, duration of treatment is 30-40 days. The maximum daily dose is 2 tablets.
Capsules
The capsules are intended for oral administration, regardless of the meal.
Recommended dosage: 1 capsule per day, course of therapy - 30-40 days. The maximum daily dose is 2 capsules.
Side effects
- allergic reactions: rarely - eyelid edema, skin rash;
- others: rarely - nausea, vomiting, metrorrhagia, dizziness, cholestatic jaundice.
Overdose
Symptoms of an overdose of Sagenita are hemorrhagic shock and metrorrhagia. In this case, the drug is immediately canceled, blood transfusion and parenteral administration of blood substitutes are prescribed.
special instructions
Patients with diabetes should take into account that the sucrose content in one capsule is 50 mg.
Influence on the ability to drive vehicles and complex mechanisms
Since taking Sagenit can cause the development of dizziness, women should be careful during therapy when driving or performing other potentially dangerous types of work.
Application during pregnancy and lactation
Sagenit is contraindicated for use during pregnancy and during breastfeeding.
Pediatric use
The drug is not prescribed for children.
With impaired renal function
The drug should be used with caution in patients with renal insufficiency.
For violations of liver function
The drug should be used with caution in patients with impaired liver function.
Drug interactions
With the simultaneous use of Sagenit:
- anticoagulants, antiarrhythmic, diuretic and antihypertensive drugs - enhance their effect;
- androgens - weaken their effect;
- thyroid preparations and folic acid - increase the therapeutic effect of sygetin.
Analogs
Analogues of Sagenit are: Sigetin, Klimadinon, Tsimiciplant, Sigetin-standard, Abyufen, Soyfem.
Terms and conditions of storage
Keep out of the reach of children.
Store in a dry place at temperatures up to 25 ° C.
Shelf life: tablets - 2 years, capsules - 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Sagenite
Numerous reviews of Sagenit confirm that the drug effectively eliminates hot flashes and other symptoms of premenopause and menopause within 2-3 weeks after administration. There are no reports of adverse drug reactions. Some patients do not like the high price of Sagenit, but in many cases it is cheaper than analogues.
Price for Sagenit in pharmacies
The approximate price for Sagenit in the form of tablets is 6193903 rubles (for a package containing 30 pcs.). The cost of the drug in the form of capsules is unknown, since this dosage form is not available for sale.
Sagenit: prices in online pharmacies
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Drug name Price Pharmacy |
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Sagenit 100 mg capsules 30 pcs. 697 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
