Omnitus - Instructions For The Use Of Tablets And Syrup, Price, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Omnitus

Omnitus: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. For violations of liver function
12. 12. Drug interactions
13. 13. Analogs
14. 14. Terms and conditions of storage
15. 15. Terms of dispensing from pharmacies
16. 16. Reviews
17. 17. Price in pharmacies

Latin name: Omnitus

ATX code: R05DB13

Active ingredient: butamirate

Manufacturer: Hemofarm (Serbia)

Description and photo update: 2018-22-10

Prices in pharmacies: from 120 rubles.

Buy

Omnitus is an antitussive agent with expectorant, anti-inflammatory and mild bronchodilatory properties.

Release form and composition

• modified release film-coated tablets: round, biconvex; 20 mg - from yellow to orange, 50 mg - dark red (10 pcs. In blisters, in a cardboard box 1 blister);
• syrup: viscous colorless transparent liquid with vanilla aroma (200 ml each in dark glass vials, sealed with plastic caps with first opening control, in a cardboard box 1 bottle with a 5 ml measuring spoon and a notch for measuring the volume of 2.5 ml).

Pills

Composition of 1 tablet:

• active substance: butamirate citrate - 20 or 50 mg;
• auxiliary components (their content for tablets 20/50 mg): lactose monohydrate (218.5 / 230.5 mg), hypromellose (70/85 mg), talc (10/10 mg), anhydrous colloidal silicon dioxide (2/6 mg), magnesium stearate (8/12 mg), povidone (1.5 / 1.5 mg);
• the composition of the film shell (for tablets 20/50 mg): talc (4.7 / 4.95 mg), macrogol (1.253 / 1.273 mg), ethylcellulose (3.14 / 3.183 mg), hypromellose (5.105 / 5.305 mg), titanium dioxide (1.041 / 1.061 mg); in tablets 20 mg - dye "Sunset Sun" yellow (E 110) (11%) (1.261 mg), in tablets 50 mg - crimson dye "Ponso" 4R (E 124) (2.122 mg) and brown varnish [black dye (E151), dye azorubin (E122), dye "Sunset" yellow (E110)] (0.106 mg).

Syrup

Composition of 1 ml of syrup:

• active substance: butamirate citrate - 0.8 mg;
• auxiliary components: sodium hydroxide (0.1 mg), benzoic acid (1.15 mg), glycerol (290 mg), sodium saccharinate (0.6 mg), sorbitol 70% non-crystallizing (405 mg), ethanol 96% (0.003 ml), anise oil (0.15 mg), vanillin (0.6 mg), purified water (up to 1 ml).

Pharmacological properties

Pharmacodynamics

Butamirate citrate - the active ingredient of Omnitus - has a direct effect on the cough center, improves spirometry and blood oxygenation.

The substance is neither pharmacologically nor chemically related to the opium alkaloids.

Pharmacokinetics

Butamirate citrate is characterized by high absorption. After taking a tablet at a dose of 50 mg, the maximum concentration (C _max) in the plasma of the main metabolite is observed after 9 hours and is 1.4 μg / ml, after taking a syrup at a dose of 150 mg, C _max is observed after 1.5 hours, equal to 6.4 μg / ml. Has no cumulative effect.

Butamirate citrate is rapidly hydrolyzed in plasma to diethylaminoethoxyethanol and 2-phenylbutyric acid. Both metabolites also have antitussive effects. They are characterized by a high bond with plasma proteins, due to which they are in the plasma for a long time. 2-phenylbutyric acid, the main metabolite, is further oxidized to 14C-p-hydroxy-2-phenylbutyric acid. All of these metabolites are excreted through the kidneys. Acid metabolites are mainly associated with glucuronic acid.

Indications for use

According to the instructions, Omnitus is intended for the treatment of dry coughs of any etiology (including whooping cough, flu, and colds).

Also, the drug is prescribed to suppress cough during bronchoscopy, surgical interventions, in the pre- and postoperative period.

Contraindications

• lactation period;
• hypersensitivity to drug components.

Additional contraindications for tablets:

• pregnancy;
• children's age: for a dosage of 20 mg - up to 6 years, for a dosage of 50 mg - up to 18 years;

Additional contraindications for syrup:

• I trimester of pregnancy;
• children under 3 years old.

Instructions for the use of Omnitus: method and dosage

Both dosage forms of Omnitus are intended for oral administration.

Pills

Omnitus tablets are recommended to be taken before meals, swallowing whole.

At a dosage of 50 mg, tablets are prescribed for adults - 1 pc. every 8-12 hours

At a dosage of 20 mg tablets are prescribed as follows:

• adults - 2 pcs. 2-3 times a day;
• teenagers from 12 years old - 1 pc. 3 times a day;
• children 6-12 years old - 1 pc. 2 times a day.

Syrup

Dosages of syrup depending on age:

• adults - 30 ml 3 times a day;
• children from 9 years old (weighing 40 kg) - 15 ml 4 times a day;
• children 6-9 years old (22-30 mg) - 15 ml 3 times a day;
• children 3-6 years old (15-22 kg) - 10 ml 3 times a day.

1 full scoop corresponds to 4 mg of butamirate (volume of 5 ml of syrup).

Side effects

Omnitus can cause allergic reactions, dizziness, nausea, diarrhea, exanthema.

Overdose

In case of an overdose of the drug, the following symptoms occur: decrease in blood pressure, dizziness, drowsiness, nausea, diarrhea, vomiting.

First of all, the intake of activated charcoal and saline laxatives is shown. Further treatment is symptomatic (if indicated).

special instructions

Diabetes mellitus is not a contraindication to the use of Omnitus. The syrup contains saccharin and sorbitol as a sweetener. The tablets contain lactose.

In the form of a syrup, Omnitus contains ethanol: in 1 ml - 0.003 ml. A single dose (10 ml of syrup) contains 0.03 ml.

Because of the ethanol in the syrup, it is dangerous for pregnant women, children, patients with brain and liver diseases, epilepsy and alcoholism.

Influence on the ability to drive vehicles and complex mechanisms

No information available.

Application during pregnancy and lactation

In the form of a syrup, Omnitus is contraindicated for the entire period of pregnancy, in the form of tablets - in the first trimester.

If it is advisable to take the drug during lactation, it is recommended to temporarily stop breastfeeding.

Pediatric use

Age restrictions for different forms of Omnitus release:

• up to 3 years - for syrup;
• up to 6 years - for tablets 20 mg;
• up to 18 years old - for tablets of 50 mg.

For violations of liver function

Omnitus syrup contains ethanol, which is why this dosage form of the drug poses a potential danger to patients with liver disease.

Drug interactions

During treatment, you must refrain from drinking alcoholic beverages. You should not take drugs that depress the central nervous system, such as tranquilizers, antipsychotics, and sleeping pills.

Interactions of butamirate with other drugs have not been described.

Analogs

Omnitus analogs are Codelac Neo, Sinekod, Panatus, Panatus Forte.

Terms and conditions of storage

Shelf life of different dosage forms:

• tablets - 2 years;
• syrup - 5 years.

Storage conditions: dry (for tablets), protected from light and inaccessible to children, with an ambient temperature of 15 to 25 ° C.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Omnitus

According to reviews, Omnitus is an effective, fast-acting and inexpensive drug that eliminates dry cough of various etiologies.

In the form of a syrup, the product has a pleasant taste, it is convenient to give it to children.

The disadvantages of some patients include the high content of dyes in Omnitus tablets, in their opinion, very harmful (it is not clear what they are needed for).

Omnitus price in pharmacies

The price for Omnitus is:

• 125–220 rubles per pack of 10 tablets with a dosage of 20 mg;
• 170-260 rubles for a pack of 10 tablets with a dosage of 50 mg;
• 145-190 rubles for 1 bottle of syrup.

Omnitus: prices in online pharmacies

Drug name Price Pharmacy

Omnitus 20 mg modified release film-coated tablets 10 pcs. 120 RUB Buy

Omnitus 50 mg modified release film-coated tablets 10 pcs. 149 r Buy

Omnitus 0.8 mg / ml syrup 200 ml 1 pc. 177 r Buy

Omnitus syrup 0.8mg / ml 200ml 217 r Buy

Omnitus tablets 50mg 10 pcs. 229 r Buy

Omnitus tablets 20mg 10 pcs. 232 RUB Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!