Sub Simplex - Instructions, Application For Newborns, Reviews, Price

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Sub Simplex

Sub Simplex: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Sab Simplex

ATX code: A03AX13

Active ingredient: Simethicone (Simethicone)

Manufacturer: Pfizer (USA)

Description and photo update: 2019-07-08

Prices in pharmacies: from 339 rubles.

Buy

Sub Simplex is a drug that helps to reduce flatulence.

Release form and composition

The dosage form is a suspension for oral administration: from gray-white to white, somewhat viscous, has a characteristic fruity (vanilla-raspberry) odor (in glass dark dropper bottles, 30 ml each (1 ml = 25 drops), 1 bottle each -droplet in a cardboard box).

Composition of 100 ml suspension:

• active substance: simethicone - 6.919 g (silicon dioxide: dimethicone 350, in a ratio of 7.5%: 92.5%);
• additional components: raspberry flavor - 0.108 g, hypromellose - 1.5 g, carbomer - 0.6 g, sodium citrate dihydrate - 1 g, citric acid monohydrate - 0.5468 g, vanilla flavor - 0.315 g, sodium cyclamate - 0, 2 g, sodium saccharinate - 0.02 g, sodium benzoate - 0.1 g, polyglycostearyl acid esters - 1.0378 g, sorbic acid - 0.0347 g, water - 89.6189 g.

Pharmacological properties

Pharmacodynamics

By reducing the surface tension at the interface, simethicone - the active component of Sub Simplex - inhibits the formation and ensures the destruction of gas bubbles in the intestinal contents. The gases that are released during this can be absorbed by the intestinal walls or excreted due to peristaltic activity.

In X-ray and sonography, simethicone prevents overlap and interference in images and provides better irrigation of the colon mucosa with contrast agent, preventing damage to the contrast film.

The active ingredient Sub Simplex changes the surface tension of gas bubbles that form in the contents of the stomach and intestinal mucus, which leads to their destruction. The released gases are absorbed into the intestinal walls or are excreted during intestinal peristalsis. Simethicone provides a physical removal of foam and does not participate in chemical reactions.

Pharmacokinetics

Since simethicone is physically and chemically inert, it is not absorbed in the body and, after passing through the gastrointestinal tract, is excreted unchanged.

Indications for use

• flatulence, increased gas production, including those arising in the postoperative period (as symptomatic therapy);
• poisoning with detergents in an acute course when they enter the stomach;
• preparation for diagnostic studies of the gastrointestinal tract (X-ray, ultrasound, esophagogastroduodenoscopy).

Contraindications

• intestinal obstruction;
• obstructive diseases of the gastrointestinal tract;
• hypersensitivity to the substances included in the suspension.

Instructions for the use of Sab Simplex: method and dosage

Suspension Sab Simplex is taken orally, preferably at the same time or after meals and, if necessary, before bedtime.

The recommended regimen for the use of the drug in the treatment of increased gas formation (0.2 ml = 5 drops):

• newborns and children under 1 year old on artificial feeding: a single dose - 15 drops (added to baby food (in each bottle) or given undiluted from a spoon before feeding). The suspension mixes well with liquids, including milk;
• children 1-6 years old: a single dose - 15 drops, at the same time or after a meal, it is possible to take an additional single dose at night;
• children 6-15 years old: single dose - 20-30 drops, frequency of administration - 4-6 times a day (preferably at regular intervals);
• adults: single dose - 30-45 drops, frequency of administration - 4-6 times a day (preferably at regular intervals).

The duration of the course is determined by the indications (complaints). Long-term therapy is possible.

Shake the bottle with Sub Simplex actively before taking it. To deliver the suspension from the pipette, turn the bottle upside down and knock on its bottom.

The recommended regimen for the use of the drug in preparation for diagnostic studies of the gastrointestinal tract (5 ml = 1 teaspoon):

• X-ray: 3-6 teaspoons in the evening on the eve of the study day;
• Ultrasound: 3 teaspoons in the evening on the eve of the study day and 3 hours before the study;
• endoscopy: 0.5-1 teaspoon before examination, additionally during endoscopy, several milliliters of suspension are injected through the endoscope.

When taking the drug during preparation for the study, it is recommended to remove the pipette.

Doses of Sub Simplex in case of poisoning with detergents are determined by the severity of the condition. The minimum recommended dose is 1 teaspoon.

Side effects

Allergic reactions may develop while taking the drug.

Overdose

Overdose cases were not observed.

special instructions

New / recurring complaints due to increased gas production must be clinically confirmed.

Influence on the ability to drive vehicles and complex mechanisms

Taking the drug does not affect the ability to drive or perform work that requires quick reactions and increased concentration.

Application during pregnancy and lactation

According to the instructions, Sub Simplex can be used during pregnancy and during breastfeeding, if indicated.

Pediatric use

The drug is used to treat children. Sub Simplex for newborns and children under one year old who are bottle-fed is added to the bottle with nutrition. Sub Simplex for newborns and breastfed babies is given with a spoon before feeding.

Drug interactions

There are no data on the interaction of Sub Simplex with other drugs / substances.

Analogs

Analogs of Sab Simplex are: Espumisan, Colikid, Simot, Infacol, Metsil, Kuplaton, Disflatil, Bobotik, Antiflat Lannacher,

Terms and conditions of storage

Keep out of reach of children at temperatures up to 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Sub Simplex

According to reviews, Sab Simplex is an effective remedy for increased gas production in newborns, preschool and school children and adults. There are practically no side effects during treatment.

Price for Sub Simplex in pharmacies

The price for a bottle of Sub Simplex in most pharmacies varies from 280 to 350 rubles.

Sub Simplex: prices in online pharmacies

Drug name Price Pharmacy

Sub simplex 69.19 mg / ml oral suspension 30 ml 1 pc. 339 r Buy

Sub Simplex suspension for internal approx. 69.19mg / ml 30ml 349 r Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!