Odeston
Odeston: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Odeston
ATX code: A05AX02
Active ingredient: hymecromone (hymecromone)
Manufacturer: PHARMACEUTICAL WORKS POLFA in Pabianice, Joint-Stock Company (Poland)
Description and photo update: 2019-20-08
Prices in pharmacies: from 296 rubles.
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Odeston is a choleretic drug that also has a selective antispasmodic effect on the sphincter of Oddi and bile ducts. Does not reduce blood pressure and peristalsis of the gastrointestinal tract.
Release form and composition
Dosage form - tablets: round, flat-cylindrical, from white to white with a yellowish tinge, on one side - engraving "Ch" and chamfer (10 or 50 pcs. In a blister, in a cardboard box, respectively 5 or 1 blister).
Active ingredient: gimecromone, its content in 1 tablet is 200 mg.
Additional components: gelatin, potato starch, magnesium stearate.
Pharmacological properties
Gimecromone stimulates the formation and further excretion of bile, and also reduces the stagnation of bile and prevents the crystallization of cholesterol, thereby preventing the occurrence of cholelithiasis.
Pharmacodynamics
Detailed studies of the pharmacodynamics of the drug have not been conducted.
Pharmacokinetics
When taken orally, gimecromone is easily absorbed from the gastrointestinal tract, the degree of its binding to blood plasma proteins is negligible. The maximum concentration of the active component in the blood plasma is recorded 2–3 hours after ingestion. The half-life is approximately 1 hour. Excretion of gimecromone is carried out through the kidneys (approximately 93% of the dose taken - in the form of glucuronate, 1.4% - in the form of sulfonate, 0.3% - unchanged).
Indications for use
- Decreased appetite, constipation, nausea, vomiting due to hyposecretion of bile;
- Non-calculous chronic cholecystitis, cholelithiasis, cholangitis;
- Dyskinesia of the sphincter of Oddi and biliary tract of the hyperkinetic type;
- Condition after surgical interventions on the biliary tract and gallbladder.
Contraindications
Absolute:
- Crohn's disease;
- Obstruction of the biliary tract;
- Ulcerative colitis;
- Hepatic and renal failure;
- Peptic ulcer and 12 duodenal ulcer;
- Hemophilia;
- Age under 18;
- Hypersensitivity to any component of the drug.
Due to the lack of data on the safety of use during pregnancy and lactation, Odeston can be prescribed only if the expected benefit to the woman outweighs the potential risks to the fetus / child.
Instructions for the use of Odeston: method and dosage
Odeston tablets should be taken orally 30 minutes before meals.
Depending on the condition, 1-2 tablets are prescribed 3 times a day.
The duration of therapy is 2 weeks.
Side effects
- From the digestive system: abdominal pain, flatulence, diarrhea, ulceration of the mucous membrane of the gastrointestinal tract;
- Others: headache and allergic reactions.
Overdose
There are no reports of cases of Odeston overdose in humans.
special instructions
Influence on the ability to drive vehicles and complex mechanisms
Odeston does not negatively affect the speed of reactions and the ability to concentrate, therefore, it can be used to treat people regardless of their field of activity.
Application during pregnancy and lactation
There is no information about the safety of using the drug in pregnant and lactating women. The appointment of Odeston during pregnancy and lactation is permissible only in cases where the potential benefits of therapy for the mother significantly outweigh the possible risks for the fetus or child.
Pediatric use
The drug is not prescribed for children and adolescents under the age of 18.
With impaired renal function
It is contraindicated to take Odeston in the presence of renal failure.
For violations of liver function
According to the instructions, Odeston is contraindicated in the presence of liver failure.
Drug interactions
Morphine reduces the effect of gimecromone by causing spasm of the sphincter of Oddi.
With the simultaneous use of metoclopramide, a mutual decrease in the effectiveness of both drugs is noted.
Gimecromone enhances the effect of indirect anticoagulants.
Analogs
Odeston's analogues are: Allohol-UBF, Allohol, Holenzim, Holagol, Berberine, etc.
Terms and conditions of storage
Store out of the reach of children at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Odeston
Patients suffering from bile metabolism disorders leave numerous reviews about Odeston, noting its high efficiency. Provided that the course of therapy is combined with an appropriate diet, the drug helps to get rid of such unpleasant symptoms as nausea, heaviness in the stomach, and a bitter taste in the mouth. Experts also treat Odeston positively, reporting that treatment usually eliminates stagnation of bile, activates its secretion and helps to normalize digestion. However, it is not recommended to self-medicate: before you start taking the drug, you should contact a specialist and undergo an appropriate examination.
Price for Odeston in pharmacies
On average, the price of Odeston in pharmacy chains is 494-685 rubles per pack, including 50 tablets.
Odeston: prices in online pharmacies
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Drug name Price Pharmacy |
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Odeston 200 mg tablets 20 pcs. 296 r Buy |
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Odeston tablets 200mg 20 pcs. RUB 350 Buy |
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Odeston 200 mg tablets 50 pcs. 480 RUB Buy |
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Odeston tablets 200mg 50 pcs. 494 r Buy |
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Odeston 200 mg tablets 100 pcs. 735 RUB Buy |
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Odeston tablets 200mg 100 pcs. 859 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
