Rennie
Rennie: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Rennie
ATX code: A02AX
Active ingredient: calcium carbonate + magnesium carbonate
Producer: Delpharm Giallard (France)
Description and photo update: 2019-10-09
Prices in pharmacies: from 156 rubles.
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Rennie is a combined drug with an antacid effect that promotes rapid and long-term neutralization of excess gastric acid hydrochloric acid.
Release form and composition
Rennie's dosage forms:
- Chewable tablets: square, with concave surfaces, from white with a light brown tint to white, engraved with "Rennie" on both sides, have the smell of menthol (2 pcs. In strips, in a cardboard box 18 strips; 6 pcs. In blisters, in a cardboard box 2, 4, 6, 8 or 16 blisters; 12 pcs. in blisters, in a cardboard box 1-4 or 8 blisters);
- Chewable tablets (cooling taste): square, with concave surfaces, from white with a light brown tint to white, light cream stains are acceptable, engraved "Rennie" on both sides, have the smell of menthol (6 pcs. In blisters, in a cardboard box 2, 4, 6, 8 or 16 blisters; 12 pcs. in blisters, in a cardboard box 1-4 or 8 blisters);
- Chewable tablets without sugar (mint): square, with concave surfaces, white with a creamy tinge, engraved "Rennie" on both sides, have a mint smell (2 pcs. In strips, in a cardboard box 18 strips; 6 pcs. In blisters, in a cardboard box 2, 4, 6, 8 or 16 blisters; 12 pcs. in blisters, in a cardboard box 1-4 or 8 blisters);
- Chewable tablets without sugar (cooling taste): square, with concave surfaces, white with a creamy shade, light cream stains are acceptable, engraving "Rennie" on both sides, have a mint smell (2 pcs. In strips, in a cardboard box 18 strips; 6 pcs. in blisters, in a cardboard box 2, 4, 6, 8 or 16 blisters; 12 pcs. in blisters, in a cardboard box 1-4 or 8 blisters);
- Chewable tablets (orange): square, with concave surfaces, white with a creamy tinge, engraved "Rennie" on both sides, have the smell of orange (6 pcs. In blisters, in a cardboard box of 2, 4, 6, 8 or 16 blisters; 12 pcs. in blisters, in a cardboard box 1-4 or 8 blisters).
Each pack also contains instructions for using Rennie.
Active ingredients in 1 tablet (any dosage form):
- Calcium carbonate - 680 mg;
- Basic magnesium carbonate 80 mg
Auxiliary components as part of 1 tablet:
- Chewable tablets: sucrose - 475 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 33.14 mg, magnesium stearate - 10.66 mg, liquid light paraffin - 5 mg, menthol flavor (peppermint oil, gum arabic, maltodextrin, silicon dioxide) - 13 mg, lemon flavor (maltodextrin, lemon oil, water) - 0.2 mg;
- Chewable tablets (cooling taste): sucrose - 475 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 33.14 mg, magnesium stearate - 10.66 mg, liquid light paraffin - 5 mg, xylitab 100 (xylitol ≥95%, polydextrose) - 25.2 mg, cooling flavor (maltodextrin, diethyl malonate, methyl lactate, menthol, modified starch (E1450), isopulegol) - 15 mg, menthol flavor (menthol, maltodextrin, modified starch) (E1450) - 15 mg;
- Chewable tablets without sugar (mint): sorbitol - 400 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 35.5 mg, magnesium stearate - 10.7 mg, liquid paraffin - 5 mg, mint flavor - 10 mg, sodium saccharinate - 0.8 mg;
- Sugar-free chewable tablets (cooling flavor): sorbitol 400 mg, pregelatinized corn starch 20 mg, potato starch 13 mg, talc 35.5 mg, magnesium stearate 10.7 mg, liquid paraffin 5 mg, cooling flavor 15 mg, mint flavor 8 mg, sodium saccharinate 0.8 mg;
- Chewable tablets (orange): sucrose 475 mg, pregelatinized corn starch 20 mg, potato starch 13 mg, talc 33.14 mg, magnesium stearate 10.66 mg, liquid paraffin 5 mg, orange flavor (orange oil, maltodextrin, purified water) - 35.2 mg, sodium saccharinate - 2 mg.
Pharmacological properties
Pharmacodynamics
Rennie is an antacid drug. Its active ingredients - calcium carbonate and magnesium carbonate - provide fast and long-term neutralization of excess gastric acid hydrochloric acid, which has a protective effect on the gastric mucosa.
The therapeutic effect is achieved in 3-5 minutes, which is due to the high calcium content and good solubility of the tablets.
Pharmacokinetics
As a result of the interaction of active components with gastric juice, the formation of soluble magnesium and calcium salts occurs in the stomach. The degree of absorption of magnesium and calcium from these compounds depends on the dose. The maximum values of the indicator: calcium - 10%, magnesium - 15-20%.
The absorbed calcium and magnesium in small amounts are excreted by the kidneys. Insoluble compounds are formed from soluble salts in the intestine, which are subsequently excreted in the feces.
Plasma concentrations of magnesium and calcium may increase in patients with impaired renal function.
Indications for use
Rennie is prescribed for symptoms associated with reflux esophagitis and increased acidity of gastric juice, namely:
- Heartburn;
- Feeling of heaviness or fullness in the epigastric region;
- Recurrent pain in the stomach;
- Dyspeptic phenomena, including conditions associated with the intake of drugs, dietary errors, abuse of coffee, alcohol, nicotine;
- Dyspepsia of pregnant women;
- Sour belching.
Contraindications
- Nephrocalcinosis;
- Hypercalcemia;
- Renal failure in severe course;
- Hypophosphatemia;
- Age under 12;
- Fructose intolerance, isomaltase / sucrase deficiency, glucose-galactose malabsorption (for chewable tablets / chewable tablets (cooling taste));
- The presence of hypersensitivity to the components of the drug.
Rennie, instructions for use: method and dosage
Rennie's tablets are taken orally, chewed or held until completely dissolved in the mouth. The drug should be taken when the first symptoms appear.
Single dose - 1-2 tablets. If necessary, it is possible to repeat the drug administration after 2 hours.
The maximum dose is 11 tablets per day.
Side effects
The drug is generally well tolerated if the recommended doses are observed.
During the use of Rennie, the development of hypersensitivity reactions to the components of the drug in the form of a rash, Quincke's edema, anaphylactic reactions may be observed.
Overdose
The main symptoms (with prolonged use of Rennie in patients with impaired renal function): hypermagnesemia, hypercalcemia, alkalosis, which manifests itself in the form of nausea, vomiting, muscle weakness.
Therapy: Canceling Rennie. Medical advice is required.
special instructions
When Rennie is prescribed for functional disorders of the kidneys, it is necessary to regularly monitor the serum concentration of magnesium, calcium and phosphorus.
Long-term therapy in high doses is not recommended for functional disorders of the kidneys.
When high doses of Rennie are taken, the likelihood of kidney stones increases.
Each chewable tablet / chewable tablet (orange) / chewable tablet (cooling flavor) contains 475 mg of sucrose; in a sugar-free tablet (mint) / sugar-free chewing tablet (cooling taste) - 400 mg of sorbitol (may be used in diabetes mellitus).
In case of ineffectiveness of therapy, you should consult a specialist.
Application during pregnancy and lactation
Rennie, taken by a pregnant / lactating woman in the recommended doses, does not pose a threat to the health of the fetus / child.
Pediatric use
For patients under 12 years of age, the drug is not prescribed.
With impaired renal function
In case of severe renal failure, Rennie's tablets are contraindicated.
Drug interactions
With the combined use of Rennie with certain drugs / substances, the following effects may be observed:
- Thiazide diuretics: development of interaction (it is necessary to regularly monitor serum calcium concentration);
- Antibiotic drugs of the tetracycline series, drugs of phosphates, iron, fluorides, fluoroquinolones, levothyroxine, cardiac glycosides: a decrease in their absorption;
- Other drugs taken at the same time: a decrease in their speed and degree of absorption (due to a change in the acidity of gastric juice associated with Rennie's intake; other drugs should be taken at an interval of 1-2 hours).
Analogs
Rennie's analogues are: Almagel, Alumag, Gastal, Inalan, Maalox, Sekrepat Forte.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Shelf life Rennie in blisters:
- Chewable tablets - 5 years;
- Other forms of release - 3 years.
Shelf life of Rennie in strips is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Rennie
Reviews about Rennie are in most cases positive. Patients recommend it for its high efficiency, pleasant taste, the possibility of using during pregnancy and lactation, ease of packaging. In some cases, they indicate a short therapeutic effect. The cost is estimated in different ways - from affordable to high.
Price for Rennie in pharmacies
The approximate price for Rennie is 166-173 rubles. (12 tablets in a package), 291-296 rubles. (24 tablets in a package) or 419–461 rubles. (in a package of 48 tablets).
Rennie: prices in online pharmacies
Drug name Price Pharmacy |
Rennie 680 mg + 80 mg menthol flavored chewable tablets 12 pcs. 156 r Buy |
Rennie 680 mg + 80 mg orange flavor chewable tablets 12 pcs. 157 r Buy |
Rennie 680 mg + 80 mg sugar-free mint chewable tablets 12 pcs. 158 RUB Buy |
Rennie chewable tablets. sugar-free mint 12 pcs. 168 RUB Buy |
Rennie chewable tablets. menthol 12 pcs. 168 RUB Buy |
Rennie 680 mg + 80 mg menthol flavored chewable tablets 24 pcs. 235 RUB Buy |
Rennie 680 mg + 80 mg Orange Flavor Chewable Tablets 24 pcs 235 RUB Buy |
Rennie chewable tablets. orange 24 pcs. 242 r Buy |
Rennie chewable tablets. menthol 24 pcs. 242 r Buy |
Rennie 680 mg + 80 mg sugar-free mint chewable tablets 24 pcs. 244 RUB Buy |
Rennie chewable tablets. sugar-free mint 24 pcs. 266 r Buy |
Rennie 680 mg + 80 mg tablets chewable cooling flavor without sugar 24 pcs. 325 RUB Buy |
Rennie 680 mg + 80 mg orange flavor chewable tablets 48 pcs 351 r Buy |
Rennie 680 mg + 80 mg sugar-free mint chewable tablets 48 pcs. 353 r Buy |
Rennie chewable tablets. orange 48 pcs. 406 r Buy |
Rennie chewable tablets. sugar-free mint 48 pcs. 415 RUB Buy |
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Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!