Regulax Picosulfate
Regulax Picosulfate: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Regulax Picosulfate
ATX code: A06AB08
Active ingredient: sodium picosulfate (Sodium picosulfate)
Producer: Krewel Meuselbach, GmbH (Germany)
Description and photo update: 2019-05-12
Prices in pharmacies: from 255 rubles.
Buy
Regulax Picosulfate is an oral laxative.
Release form and composition
The drug is produced in the form of drops for oral administration: a colorless transparent solution (10, 20 or 50 ml each in a glass brown bottle with a dropper stopper and a white screw cap; in a cardboard box 1 bottle and instructions for use of Regulax Picosulfate).
1 ml of solution contains:
- active substance: sodium picosulfate monohydrate - 7.5 mg;
- additional components: propylene glycol, non-crystallizing sorbitol solution 70%, purified water.
Pharmacological properties
Pharmacodynamics
The active ingredient of Regulax Picosulfate - sodium picosulfate, is a laxative. Formed by hydrolysis under the influence of intestinal microorganisms, its active form directly excites the nervous structures of the intestinal wall, which reduces the absorption of electrolytes and water, and accelerates the transit of intestinal contents. The drops take effect 10-12 hours after ingestion.
Pharmacokinetics
The drug after oral administration is not absorbed from the gastrointestinal tract (GIT), and also does not undergo hepatic-intestinal circulation.
Indications for use
Regulax Picosulfate is used to facilitate defecation in case of atonic constipation and to regulate stool in case of proctitis, hemorrhoids, and fissures of the anus.
Also, the drug is recommended for use to prepare a patient for instrumental and X-ray examinations, surgical operations.
Contraindications
Absolute:
- strangulated hernia;
- spastic constipation;
- intestinal obstruction;
- acute diseases of the abdominal organs, of an inflammatory nature;
- abdominal pain of unexplained genesis;
- peritonitis;
- bleeding from the gastrointestinal tract;
- severe dehydration;
- metrorrhagia;
- cystitis;
- age up to 4 years;
- I trimester of pregnancy;
- hypersensitivity to any of the constituents of the drug.
Care should be taken to treat with the drug during lactation.
Regulax Picosulfate, instructions for use: method and dosage
Drops Regulax Picosulfate are taken orally at bedtime.
For adults, it is recommended to start treatment with a dose of 13 drops; with persistent constipation, it can be increased to 26 drops. In the future, taking into account the effect obtained, the dose can be adjusted. Children over 4 years old should take the drug in an initial dose of 5–8 drops.
The course of therapy is 7 days.
Side effects
During the treatment period, the following adverse events may occur: weakness, bloating, abdominal pain, diarrhea, imbalance in water and electrolyte balance, dehydration, decreased blood pressure, convulsions.
Overdose
Symptoms of an overdose of Regulax Picosulfate may include the reactions described in the "Side effects" section. In addition, against the background of chronic overdose, the appearance of such effects as ischemia of the colon mucosa, lesions of the renal tubules, urolithiasis, secondary hyperaldosteronism is possible.
In this condition, gastric lavage, antispasmodic administration, correction of water-electrolyte disturbances are prescribed.
special instructions
Do not use the drug for more than 7 days without medical supervision.
Long-term use in most cases exacerbates the risk of worsening intestinal fixation.
Since Regulax Picosulfate drops contain sugar substitutes, the drug can be taken by patients with diabetes mellitus. 1 ml corresponds to 0.03 bread units (XE).
Application during pregnancy and lactation
In the first trimester of pregnancy, drug treatment is contraindicated. In the II-III trimesters, repeated use of a laxative can be performed only after a thorough assessment of the need for its use and possible risks, since there is not enough information about drug treatment during pregnancy.
During breastfeeding, Regulax Picosulfate should be used with caution.
Pediatric use
The drug is contraindicated in children under 4 years of age. In children over 4 years of age, therapy can be carried out only by agreement with the doctor, while the initial dose of the drug should be no more than 5-8 drops, and the course of treatment for a maximum of 7 days.
Drug interactions
- diuretics, glucocorticosteroids: the threat of electrolyte disturbances increases;
- cardiac glycosides: sodium picosulfate can increase the body's sensitivity to these drugs;
- broad-spectrum antibiotics: reduce the laxative effect of sodium picosulfate.
Analogs
Analogs of Regulax Picosulfate are Laxigal, Guttasil, Guttalaks, Pikodinar, Slabilen, Slabikap, Laxigal-Teva, etc.
Terms and conditions of storage
Store out of the reach of children at a temperature of 15-25 ° C.
Shelf life - 5 years, after the first opening of the bottle - 6 months.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Regulax Picosulfate
According to most reviews, Regulax Picosulfate is an affordable and effective laxative that helps with constipation, including persistent ones. Patients recommend starting treatment with caution, starting with a minimum dose. Then, depending on the result obtained, gradually select the optimal dose for yourself. According to patients, the drug should be used as little as possible, so as not to cause addiction and dependence.
The disadvantages of many include the presence of contraindications and the development of side effects, including severe abdominal pain, severe weakness, a drop in blood pressure. In rare cases, it is noted that the drug did not have the desired effect, without solving the problem with the stool.
Price for Regulax Picosulfate in pharmacies
The price for Regulax Picosulfate can be 250-300 rubles. per bottle containing 20 ml drops.
Regulax Picosulfate: prices in online pharmacies
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Drug name Price Pharmacy |
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Regulax Picosulfate 7.5 mg / ml drops for oral administration 20 ml 1 pc. 255 RUB Buy |
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Regulax picosulfate drops for internal approx. 7.5mg / ml 20ml 262 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
