Table of contents:
- Release form and composition
- Pharmacological properties
- Indications for use
- Revmonn, instructions for use: method and dosage
- Side effects
- special instructions
- Application during pregnancy and lactation
- Pediatric use
- With impaired renal function
- For violations of liver function
- Use in the elderly
- Drug interactions
- Terms and conditions of storage
- Terms of dispensing from pharmacies
- Reviews about Revmonna
- Price for Revmonn in pharmacies
Video: Revmonn - Instructions For Use, Price, Reviews, Analogues, Spray, Cream
Revmonn: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Revmonn
ATX code: M02AA06
Active ingredient: etofenamate (Etofenamate)
Producer: MEDA Manufacturing, GmbH (Germany)
Description and photo update: 2019-05-12
Revmonn is a non-steroidal anti-inflammatory drug (NSAID) for external use.
Release form and composition
- spray for external use 10%: transparent, colorless or pale yellow, with a specific smell of isopropanol (50 ml in a glass brown bottle with a screw-on spray dispenser, in a cardboard box 1 bottle);
- gel for external use 5 and 10%: homogeneous, transparent or with slight opalescence, almost colorless or slightly yellowish, with a specific smell of isopropyl alcohol (20, 40, 50 or 100 g in an aluminum tube, in a cardboard box 1 tube);
- cream for external use 10%: homogeneous, white (20, 40, 50 or 100 g in an aluminum tube, in a cardboard box 1 tube);
- emulsion for external use 10%: homogeneous, white (100 g in an opaque polypropylene bottle with a protective inner liner, 1 bottle in a cardboard box).
Each pack also contains instructions for using Revmonn.
1 g of spray contains:
- active substance: etofenamate - 100 mg;
- additional substances: cetomacrogol oleate, propylene glycol, macrogol-400, isopropanol, diisopropyl adipate, purified water.
1 g of gel contains:
- active substance: etofenamate - 50 or 100 mg;
- additional substances: propylene glycol (for 10% gel), cetomacrogol oleate, macrogol-400, isopropanol, carbomer 940, sodium hydroxide, purified water.
1 g of cream contains:
- active substance: etofenamate - 100 mg;
- additional substances: hyetellose, benzyl alcohol, glyceryl monostearate, citric acid, isopropyl myristate, sodium citrate, macrogol stearate, purified water.
1 g of the emulsion contains:
- active substance: etofenamate - 100 mg;
- additional substances: bentonite, benzyl alcohol, diisopropyl adipate, cetyl alcohol, glyceride monostearate, citric acid, sodium citrate dihydrate, macrogol stearate, purified water.
The active component of Revmonna is etofenamate, an NSAID that exhibits pronounced anti-inflammatory and analgesic properties. The mechanism of action of the drug lies in the indiscriminate suppression of the activity of type 1 and type 2 cyclooxygenase (COX-1 and COX-2) and a violation of the metabolism of arachidonic acid. As a result, the production of prostaglandins is blocked and the production of inflammatory mediators decreases.
The active substance of Revmonna is lipophilic in nature, which ensures a high degree of its penetration through the skin. In the future, the drug is well distributed in the affected tissue and reaches therapeutic concentrations in it. For this reason, etofenamate is mainly used in pharmaceutical preparations that are intended for external use.
The agent is characterized by accumulation in the tissue in which the inflammatory process takes place and where a therapeutic effect is required. The maximum concentrations of the active substance in plasma are observed after a single use of the drug (at a dose of 300 mg of etofenamate) in all dosage forms 12-24 hours after application and can be 19-31 ng / ml for cream and emulsion and 21-28 ng / ml - for the gel. The connection of etofenamate with plasma proteins is about 99%. After external use, the relative bioavailability of the drug does not exceed 20%. Etofenamate is excreted by the kidneys and through the intestines in the form of metabolites and their compounds formed during biotransformation.
Indications for use
- bruises, sports injuries, closed injuries, joint and soft tissue injuries;
- epicondylitis, osteoarthritis, periarthritis of the shoulder joint, lumbago; additionally for the cream - osteoarthritis, arthrosis, including arthrosis of the knee joints (gonarthrosis);
- spondyloarthritis (for cream), tendinitis, peritendinitis, tenosynovitis, ankylosing spondylitis.
- violation of the integrity of the skin at the site of application of the drug;
- a history of rhinitis, urticaria, an attack of bronchial obstruction caused by the intake of acetylsalicylic acid or other NSAIDs;
- pregnancy and lactation;
- hypersensitivity to any of the constituents of Revmonna or other NSAIDs, including acetylsalicylic acid.
Relative (the drug should be used with extreme caution):
- chronic heart failure;
- bronchial asthma;
- erosive and ulcerative defects of the gastrointestinal tract (GIT);
- severe liver and / or kidney dysfunction;
- elderly age.
Revmonn, instructions for use: method and dosage
Revmonn is used externally, applied directly to the skin over the diseased areas and spread over as large an area as possible. The course of therapy for all dosage forms of the drug can range from 7-14 days to several months. Without the advice of a specialist, the maximum duration of treatment should not exceed 14 days.
A dose of Revmonna spray released with 1 press of the dispenser contains 18 mg of etofenamate.
During one procedure, as a rule, up to 7 pressings are performed. In the course of each application, after 1-2 sprays, thoroughly grind the solution in circular movements until it dries completely on the skin.
Spray Revmonn is recommended to be applied 3-5 times a day. If necessary, an increase in the dose is allowed.
Gel, cream and emulsion
A single dose of emulsion, gel and Revmonn cream, depending on the size of the painful area, can be 1700–3300 mg (equivalent to 170–330 mg of etofenamate for 10% of the drug), which roughly corresponds to a 5–10 cm strip of gel and Revmonn cream or a spot emulsions with a diameter of 3 cm. After application, the drug should be rubbed into the skin in a circular motion. Frequency rate of application - 3-4 times a day.
After the procedure, you need to wash your hands thoroughly.
In rare cases, during therapy, the development of reversible allergic reactions in the form of itching, peeling, dermatitis, urticaria or erythema can be recorded at the site of application of Revmonna. If such violations occur, you should stop using the drug and consult a doctor.
There is no evidence of an overdose of Revmonna. In case of accidental oral administration of the drug, there is a risk of developing systemic side effects. In this case, it is recommended to carry out gastric lavage, induction of vomiting. Also prescribed intake of activated carbon, forced diuresis, symptomatic treatment. Dialysis is ineffective because etofenamate is highly protein bound (about 99%).
Revmonn is for external use only.
The drug should not be applied to mucous membranes, including the mucous membrane of the eye, as well as to eczematous inflamed or damaged skin area.
The drug should not be used under an occlusive dressing.
In the case of a long course of treatment and / or application to large surfaces due to the resorptive effect, systemic adverse reactions may occur.
Influence on the ability to drive vehicles and complex mechanisms
Revmonn does not affect the ability to drive vehicles and operate complex and potentially dangerous equipment.
Application during pregnancy and lactation
It was revealed that etofenamate passes through the placental barrier, as a result of which its use is contraindicated in pregnant women.
If Revmonn is used during lactation, the issue of transferring the child to artificial feeding should be resolved.
In pediatric practice, the use of Revmonn is contraindicated due to insufficient clinical data regarding the efficacy and safety of its use in children.
With impaired renal function
Patients with severe renal dysfunction should be treated with caution.
For violations of liver function
Patients with severe liver dysfunction are advised to use Revmonn with caution.
Use in the elderly
Elderly patients should use Revmonn with caution.
With external use of etofenamate, its interaction with other drugs / preparations has not been established.
Revmonn's analogs are Etofen, Travmon, Etogel, Thermo-rheummon, Ketoprofen, Voltaren, Ketonal, Bengei, Diklak.
Terms and conditions of storage
Store out of the reach of children at a temperature not exceeding 25 ° C.
The shelf life of the spray and cream is 3 years, the emulsion is 4 years, the gel is 5 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Revmonna
Reviews of Revmonna in the form of a spray for external use, left by patients on medical sites, are usually positive. The drug is characterized as an easy-to-use, effective anti-inflammatory and analgesic agent used for bruises, injuries, inflammation and pain in muscles and joints, acute pain in the lumbar region, tendonitis and perithendinitis, exacerbations of osteochondrosis. Patients note that Revmonn has a quick action, is well absorbed into the skin, does not leave greasy marks on clothes.
The disadvantages of the drug are sometimes referred to as its relatively high cost. There are no complaints about the development of side effects.
Price for Revmonn in pharmacies
The price of Revmonn, spray for external use 10%, for a bottle of 50 ml can be 350-520 rubles.
The price of other dosage forms of the drug is unknown, since they are not currently sold in pharmacies.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!