Xylometazoline-SOLOpharm - Instructions For Use, Drops, Spray, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Xylometazoline-SOLOpharm

Xylometazoline-SOLOpharm: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Xylometazoline-SOLOpharm

ATX code: R01AA07

Active ingredient: xylometazoline (xylometazoline)

Manufacturer: LLC "Grotex" (Russia)

Description and photo updated: 22.11.2018

Prices in pharmacies: from 18 rubles.

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Xylometazoline-SOLOpharm is a decongestant drug, alpha-adrenergic agonist.

Release form and composition

Dosage forms:

• nasal drops: clear liquid without color or light yellow (10 or 15 ml in a bottle, 1 bottle in a cardboard box);
• dosed nasal spray: clear liquid without color or light yellow (10 or 15 ml in a bottle, 1 bottle in a cardboard box).

Composition of 1 ml drops of Xylometazoline-SOLOpharm 0.05 / 0.1%:

• active substance: xylometazoline hydrochloride - 0.5 / 1 mg;
• auxiliary components: benzalkonium chloride, disodium edetate dihydrate (Trilon B), sodium hydrogen phosphate dihydrate, potassium dihydrogen phosphate, sodium chloride, water for injection.

Composition of 1 dose of Xylometazoline-SOLOpharm 35/140 mcg / dose spray:

• active substance: xylometazoline hydrochloride - 35/140 mcg;
• auxiliary components: benzalkonium chloride, disodium edetate (Trilon B), sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate, sodium chloride, water for injection.

Pharmacological properties

Pharmacodynamics

Xylometazoline is a local vasoconstrictor drug with an α2-adrenomimetic effect. In a short time and for a long time, it relieves swelling and hyperemia of the mucous membrane of the nasal cavity, restoring nasal breathing in case of rhinitis. When used in recommended doses, xylometazoline does not cause irritation and hyperemia of the mucous membrane. The action of the drug lasts up to 12 hours.

Pharmacokinetics

When applied topically, xylometazoline is practically not absorbed. Its plasma concentration remains below the detection limit.

Indications for use

• rhinitis caused by acute respiratory infections;
• acute allergic rhinitis;
• otitis media;
• eustachitis;
• hay fever;
• preparation for diagnostic procedures in the nasal cavity.

Contraindications

Absolute contraindications:

• arterial hypertension;
• glaucoma;
• severe atherosclerosis;
• tachycardia;
• hyperthyroidism;
• atrophic rhinitis;
• surgical operations on the meninges (in history);
• condition after transsphenoidal hypophysectomy;
• combined use with monoamine oxidase inhibitors and tricyclic antidepressants (the interval should be at least 2 weeks);
• age up to 2 years (for drops of 0.05% and spray 35 mcg / dose), up to 6 years (for drops of 0.1% and spray 140 mcg / dose);
• pregnancy;
• increased sensitivity to the components of the drug.

Relative contraindications:

• diabetes;
• ischemic heart disease (angina pectoris);
• hyperplasia of the prostate;
• pheochromocytoma;
• hypersensitivity to adrenergic drugs (insomnia, dizziness, arrhythmia, tremor, increased blood pressure);
• lactation period.

Instructions for the use of Xylometazoline-SOLOpharm: method and dosage

Xylometazoline-SOLOpharm is used intranasally, in each nasal passage.

Nasal drops

A 0.05% solution is intended for children 2–6 years old: 1–2 drops, 1–2 times a day.

A 0.1% solution is intended for children over 6 years old and adults: 2-3 drops 2-3 times a day.

Do not use Xylometazoline-SOLOpharm drops more than 3 times a day. The duration of use should not exceed 7 days.

Nasal spray

Spray 35 mcg / dose is intended for children 2–6 years old: 1 injection no more than 3 times a day.

Spray 140 mcg / dose is intended for children over 6 years old and adults: 1 injection (if necessary, it is possible to increase the dose), no more than 3 times a day.

In the case when the condition does not improve within 3 days, or when the symptoms intensify, a doctor's consultation is required. The duration of the drug use without a doctor's prescription should not exceed 7 days. If, against the background of prolonged use of Xylometazoline-SOLOpharm spray, the feeling of nasal congestion reappears or worsens, the drug should be discontinued and a doctor should be consulted.

Side effects

• dryness and irritation of the nasopharyngeal mucosa;
• sneezing;
• tingling sensation;
• increased secretion of discharge from the nose;
• allergic reactions;
• swelling of the mucous membrane;
• palpitations;
• tachycardia;
• arrhythmia;
• increased blood pressure;
• headache;
• nausea, vomiting;
• visual impairment;
• insomnia;
• depression (with prolonged use of high doses of the drug).

It is recommended to inform the doctor about cases of aggravation of the described side effects or the occurrence of new ones.

Overdose

Symptoms of Xylometazoline-SOLOpharm overdose: decrease in body temperature, confusion, increased side effects. Accidental ingestion of the drug can cause severe dizziness, headache, increased sweating, bradycardia, an increase in blood pressure followed by a sharp decrease, respiratory depression, coma, convulsions.

In case of overdose, symptomatic treatment is recommended.

special instructions

It is recommended to clean the nasal passages before use. Long-term use of the drug can cause the development of medication rhinitis, as well as atrophy and reactive hyperemia of the nasal mucosa.

Benzalkonium chloride, a preservative in the preparation, can cause swelling of the nasal mucosa. In this regard, when signs of congestion appear, it is necessary to replace Xylometazoline-SOLOpharm with a vasoconstrictor drug that does not contain a preservative.

Influence on the ability to drive vehicles and complex mechanisms

During therapy with Xylometazoline-SOLOpharm, care should be taken when driving vehicles and other complex mechanisms that require the speed of psychomotor reactions.

Application during pregnancy and lactation

According to the instructions, Xylometazoline-SOLOpharm is contraindicated during pregnancy.

Its use during lactation is possible according to the doctor's prescription in the case when the expected benefit to the mother outweighs the possible risk to the child.

Pediatric use

For children from 2 to 6 years old, the drug is suitable in the form of drops of 0.05%, as well as a spray of 35 μg / dose. Children over 6 years old are allowed to use the drug in doses recommended by adults.

Drug interactions

The combined use of Xylometazoline-SOLOpharm with monoamine oxidase inhibitors and tricyclic antidepressants is contraindicated due to the risk of a pronounced increase in blood pressure.

Analogs

Analogs of Xylometazoline-SOLOpharm are Galazolin, Grippostad Rino, Dlyanos, Doctor Theiss Rinotays, Zvezdochka NOZ, Xilen, Influrin, Xylometazoline, Xymelin, Nosolin, Otrivin, Rinomaris, Rinonorm, Rinorusin, Snostop, Tinostop Xylo, Evkazolin Aqua, Espazolin, etc.

Terms and conditions of storage

Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Shelf life - 2 years, after opening - 1 month.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Xylometazoline-SOLOpharm

Reviews of Xylometazoline-SOLOpharm on the Web are mostly positive. Patients note a rapid relief of nasal breathing; among the advantages are the long-term effect of the drug and the low price in comparison with analogues. However, there are isolated mentions that the drug was ineffective, as well as the occurrence of side effects in the form of dryness and irritation of the nasal mucosa.

Price for Xylometazoline-SOLOpharm in pharmacies

Estimated price for Xylometazoline-SOLOpharm:

• nasal drops 0.1%, 10 ml - 40 rubles;
• spray for children 35 mcg / dose, 15 ml - 102 rubles.

Xylometazoline-SOLOpharm: prices in online pharmacies

Drug name Price Pharmacy

Xylometazoline-SOLOpharm 0.05% nasal drops 10 ml 1 pc. RUB 18 Buy

Xylometazoline-SOLOpharm 0.1% nasal drops 10 ml 1 pc. RUB 24 Buy

Xylometazoline-SOLOpharm 35 mcg / dose nasal spray, dosed 15 ml 1 pc. RUB 104 Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!