Cordiamine
Cordiamine: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Cordiamin
ATX code: R07AB02
Active ingredient: niketamide (nikethamide)
Producer: Vector-Pharm LLC, Tatkhimfarmpreparaty OJSC, Ellara LLC, Dalkhimfarm OJSC, MIKFARM LLC, Biochemist OJSC, Tula Pharmaceutical Factory LLC, Kazan Pharmaceutical Factory CJSC, Federal State Unitary Enterprise Moscow Endocrine Plant ", JSC" Organika "(Russia)
Description and photo update: 2019-16-08
Prices in pharmacies: from 52 rubles.
Buy
Cordiamine is a drug that stimulates metabolism in the central nervous system.
Release form and composition
- Drops for oral administration (in dropper bottles of 15, 25, 30 ml, 1 bottle in a cardboard box);
- Solution for injection (in 1 or 2 ml ampoules, 5, 10 ampoules in blisters with or without an ampoule knife, 1 or 2 packs in a cardboard box or 5, 10 ampoules in a cardboard box);
- Solution for oral administration (in dropper bottles of 15 or 30 ml, 1 bottle in a cardboard box).
The composition of 1 ml of a solution and drops for oral administration, as well as a solution for injection, includes the active substance: niketamide - 250 mg.
Pharmacological properties
Pharmacodynamics
Niketamide is an analeptic drug with a mixed effect. Its mechanism of action consists in both central and peripheral effects on the nervous system. The central mechanism is due to a direct effect on the vasomotor center, localized in the medulla oblongata, which is expressed in its excitation and the associated increase in blood pressure (the effect is especially pronounced with the initial inhibition of the functioning of this center).
The peripheral effect is associated with the activation of the chemoreceptors of the carotid sinus, which provokes an increase in the frequency and depth of respiratory movements. Nicetamide does not directly affect the work of the cardiovascular system.
Pharmacokinetics
Nicetamide is highly absorbed, and the extent of absorption is not determined by administration. The substance is rapidly metabolized in the liver, forming pharmacologically inactive metabolites, which are excreted mainly in the urine.
Indications for use
Indications for Cordiamin are:
- Hypotonic conditions;
- Weakening of the respiratory function of the lungs in infectious diseases, especially during the period of convalescence;
- Shock conditions, including those arising during surgical operations and in the postoperative period, collapse, asphyxia, including newborns (as an additional remedy);
- Poisoning with painkillers, sleeping pills and narcotic drugs.
Contraindications
- Seizures of various origins, including a predisposition to their development;
- Hypersensitivity to drug components.
Instructions for the use of Cordiamine: method and dosage
The drug is administered orally (regardless of food intake) or parenterally (subcutaneously, intramuscularly and intravenously).
Intravenous solution should be injected slowly. To reduce pain with subcutaneous and intramuscular administration, novocaine can be injected into the injection site beforehand (adults - 1 ml of 0.5-1% solution, children - in accordance with age).
The doctor sets the dosage regimen individually. It is determined by the indications, the patient's age and the dosage form used.
Cordiamine drops are usually prescribed in the following single doses:
- Adults: 15-40 drops;
- Children: the number of drops is appropriate for the age.
Frequency rate of application - 2-3 times a day.
Parenteral Cordiamin is usually prescribed: for adults - 1-3 times a day, 1-2 ml; children - 0.1-0.75 ml (depending on age) subcutaneously.
Higher adult doses are: single - 2 ml, daily - 6 ml (inside and subcutaneously). In case of drug poisoning, Cordiamin is administered subcutaneously and intravenously, maximum 5 ml.
Side effects
During the use of the drug, the development of such side effects as: heart rhythm disturbances, anxiety, facial flushing, muscle twitching starting from the circular muscles of the mouth, vomiting, itching of the skin.
In case of an overdose, convulsions may occur.
Overdose
Signs of an overdose of Cordiamine include tonic-clonic seizures and an increase in the severity of adverse reactions during treatment with the drug. In this case, symptomatic therapy is recommended.
special instructions
Before starting the use of Cordiamin according to indications, as well as in cases of development of uncharacteristic symptoms, you should consult a doctor.
Application during pregnancy and lactation
According to the instructions, Cordiamin is contraindicated during pregnancy and breastfeeding.
Drug interactions
There are no data on the interaction of Cordiamine with other drugs.
Analogs
Analogues of Cordiamine are: Cordiamin-Ferein, Niketamid-Eskom, Ammonia solution, Armanor, Bemegrid.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Cordiamine
Most patients leave favorable reviews about Cordiamine. They report that it is effective in raising blood pressure. Basically, the drug is prescribed to young patients aged 20-30 years, prone to a sedentary or sedentary lifestyle, since they often experience hypotension. Cordiamine in the form of a solution for injection is often used by parents to normalize and maintain respiratory function in children suffering from infectious diseases. Specialists often use the drug when carrying out resuscitation measures in newborns with asphyxia.
Price for Cordiamin in pharmacies
On average, the price of Cordiamine in the form of a solution for injection (10 ampoules are included in the package), depending on the manufacturer, is approximately 137-283 rubles (an ampoule contains 1 ml) or 190-335 rubles (an ampoule contains 2 ml). You can buy Cordiamin drops for 85‒135 rubles (for a 25‒30 ml bottle). Oral solution is not commercially available.
Cordiamin: prices in online pharmacies
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Drug name Price Pharmacy |
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Cordiamin 25% drops for oral administration 30 ml 1 pc. 52 RUB Buy |
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Cordiamine 250 mg / ml oral solution 25 ml 1 pc. RUB 55 Buy |
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Cordiamine 250 mg / ml oral solution 30 ml 1 pc. RUB 57 Buy |
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Cordiamin 25% drops for oral administration 25 ml 1 pc. RUB 58 Buy |
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Cordiamine 250 mg / ml oral solution 30 ml 1 pc. RUB 63 Buy |
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Cordiamine 250 mg / ml oral drops 30 ml 1 pc. RUB 70 Buy |
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Cordiamine drops for internal approx. 30ml RUB 78 Buy |
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Cordiamine drops for internal use 25% 25ml RUB 86 Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. 108 RUB Buy |
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Cordiamine 250 mg / ml solution for injection 1 ml 10 pcs. 115 RUB Buy |
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Cordiamine 250 mg / ml solution for injection 1 ml 10 pcs. 127 RUB Buy |
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Cordiamin solution for injection 250mg / ml amp. 1ml No. 10 RUB 128 Buy |
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Cordiamine solution for in. 25% amp 2ml 10 pcs. RUB 128 Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. RUB 128 Buy |
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Cordiamine 250 mg / ml solution for injection 1 ml 10 pcs. RUB 128 Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. 129 RUB Buy |
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Cordiamin solution for injections 250mg / ml amp. 2ml No. 10 130 RUB Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. 130 RUB Buy |
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Cordiamine solution for in. 25% 1ml 10 pcs. 132 RUB Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. RUB 145 Buy |
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Cordiamine 250 mg / ml solution for injection 2 ml 10 pcs. 149 r Buy |
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Cordiamine 250 mg / ml solution for injection 1 ml 10 pcs. 183 r Buy |
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Cordiamine solution for in. 25% 1ml 10 pcs. 188 r Buy |
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Cordiamine solution for in. 25% 2ml 10 pcs. 192 RUB Buy |
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Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
