Drops Combinil Duo - Instructions For Use, Indications

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Combined

Instructions for use:

1. 1. Release form and composition of the drug Duo
2. 2. Pharmacological action of Duo
3. 3. Indications for the use of Duo drops
4. 4. Instructions for use
5. 5. Contraindications to the use of Duo
6. 6. Side effects of Duo
7. 7. Special instructions
8. 8. Terms and conditions of storage

Prices in online pharmacies:

from 346 rub.

Buy

Combined - topical ear and eye drops. This drug is widely used in otolaryngological practice and in ophthalmology.

Release form and composition of the drug Combinil Duo

Combinil drops are available in dropper bottles in the form of a colorless to yellow solution. One vial of the drug contains 1 ml of ciprofloxacin and 3 mg of dexamethasone. Auxiliary components: disodium edetate, bezalkonium chloride, mannitol, hydrochloric acid, hydroxypropyl betacyclodextrin, water for injection.

Pharmacological action Combinil Duo

The active components of the drug ciprofloxacin and dexamethasone provide antimicrobial and anti-inflammatory effects.

Ciprofloxacin has pronounced activity against both multiplying and dormant gram-negative bacteria. Dexamethasone is a synthetic glucocorticosteroid that acts as an anti-inflammatory and immunosuppressive agent. This component reduces capillary permeability and proliferation, local exudation, cellular infiltration, collagen deposition and fibroblast activity. Thanks to dexamethasone, Combinil Duo is able to suppress the formation of scar tissue.

The experience of using Combinil drops shows that the active ingredient of the drug ciprofloxacin perfectly penetrates into various tissues of the eye (except for the lens). The maximum concentration of the active substance is observed half an hour after instillation in the moisture of the anterior chamber. Dexamethasone penetrates well into the conjunctiva and corneal epithelium.

The auxiliary component of the drug ensures long-term preservation of the active component on the surface of the eye, increasing the duration of action and the effectiveness of the drug.

Indications for the use of Combinil Duo drops

According to the instructions, Combinil is used for infectious and inflammatory diseases of the eye and its appendages - acute and subacute conjunctivitis, keratitis, anterior uveitis, blepharitis and other inflammatory diseases of the eyelids. Drops Kombinil can be used for the prevention and treatment of infectious complications after operations on the eyeball or after trauma to the eye and its appendages.

Combinil drops can also be used for infectious and inflammatory ear diseases - acute otitis externa, acute otitis media with eardrum shunt, acute otitis media with otorrhea and granulations in the presence of a tympanic membrane shunt.

Instructions for use

In case of infectious and inflammatory processes in the cavity of the eye and its appendages, one or two drops of Combinil are instilled into the conjunctival sac every four to six hours. On the first day of treatment, instillation can be repeated every two hours.

According to the instructions of Combinil for blepharitis, bacterial conjunctivitis, it is recommended to use from five days to two weeks, with keratitis - from two to four weeks. For the prevention of inflammatory processes after operations, including perforation of the eyeball - from five days to a month. If this drug is used for more than ten days, then the patient's intraocular pressure should be monitored.

In case of infectious and inflammatory diseases of the ear, four drops of Combinil should be instilled into the auditory canal of the affected ear twice a day for a week.

Before instilling the product, the ear canal must first be rinsed and dried. Before instillation, the drug must be warmed to body temperature. Then lie down and tilt your head back to facilitate instillation. Put the required number of drops into the external auditory canal and let them drain by pulling the earlobe back and down. Until the drops have completely penetrated, the position of the head must not be changed for a minute.

Contraindications to the use of Combinil Duo

Combinil drops cannot be used for herpetic keratitis and other viral lesions of the conjunctiva and cornea, tuberculosis of the eyes, fungal lesions of the eyes, viral infections of the ear canal, perforation of the tympanic membrane. According to the instructions, Combinil Duo should not be used in children under 18 years of age, as well as with hypersensitivity to the active ingredients or to any of the auxiliary components of the drug, during pregnancy and breastfeeding.

Side effect of Combinil Duo

Instillation of the drug Combinil for a long time can lead to redness, itching of the eyes, swelling of the veins, blurred vision, as well as narrowing of the visual fields and decreased visual acuity. With prolonged use, drops of Combinil can contribute to the formation of cataracts, conjunctival hyperemia. With prolonged use of the drug, a secondary infection (bacterial or fungal) may join the underlying disease.

When drops are instilled into the external auditory canal, a feeling of discomfort in the ear, ear congestion may appear. Sometimes, when the drug is instilled, wound healing slows down, facial edema and skin rash, gustatory perversions appear.

special instructions

Prolonged use of eye drops is sometimes accompanied by an increase in intraocular pressure. An increase in intraocular pressure may be accompanied by a decrease in fields and visual acuity, damage to the optic nerve, and the formation of cataracts. Therefore, when using Combinil Duo for more than ten days, it is recommended to monitor intraocular pressure. With purulent infections in the acute period, corticosteroid drugs can significantly worsen or mask the main symptoms of the disease.

After using eye drops, the clarity of visual perception sometimes decreases. Therefore, after instilling the drug, you should not drive a car. Contact lenses can only be worn twenty minutes after the drops have been applied.

Storage conditions and periods

Drops of Combinil are stored at a temperature not exceeding 25 ° C. Shelf life is two years. After opening the bottle, the drug should be used within a month.

Combinil: prices in online pharmacies

Drug name Price Pharmacy

Combined (eye and ear drops) eye and ear drops 5 ml 1 pc. 346 r Buy

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!