Table of contents:
- Release form and composition
- Pharmacological properties
- Indications for use
- Instructions for the use of Carnitine: method and dosage
- Side effects
- special instructions
- Application during pregnancy and lactation
- Drug interactions
- Terms and conditions of storage
- Terms of dispensing from pharmacies
- Reviews about Carnitine
- The price of Carnitine in pharmacies
- Carnitine: prices in online pharmacies
Video: Carnitine - Instructions For Use, Reviews, Price, Analogues
Carnitine: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Carnitine
ATX code: A16AA
Active ingredient: Carnitine (Carnitine)
Manufacturer: Belmedpreparaty RUE (Republic of Belarus)
Description and photo update: 2018-24-10
Prices in pharmacies: from 200 rubles.
Carnitine is a drug that improves metabolism and energy supply to tissues.
Release form and composition
The dosage form of the release is a concentrate for the preparation of a solution for infusion: transparent, colorless or with a slightly yellowish tinge (in 5 ml ampoules, in a cardboard box 1 or 2 blisters of 5 ampoules).
Composition of 1 ml solution:
- active substance: carnitine chloride - 100 mg;
- auxiliary component: water for injection - up to 1 ml.
Carnitine chloride has anabolic, antithyroid and antihypoxic effects, activates fat metabolism, increases appetite, stimulates regeneration and metabolic processes, taking part in various links of energy metabolism.
Carnitine is a natural substance related to the B vitamins. It belongs to the cofactors of metabolic processes that ensure the maintenance of CoA activity.
The main effects of the drug:
- decrease in basal metabolism;
- slowing down the breakdown of carbohydrate and protein molecules;
- facilitating the penetration of mitochondrial membranes and the breakdown of long-chain fatty acids (palmitic, etc.) with the formation of acetyl-CoA, which is necessary to ensure the activity of pyruvate carboxylase in the formation of ketone bodies, gluconeogenesis, synthesis of choline and its esters, oxidative phosphorylation and formation of ATP;
- providing neurotrophic effects, improving protein and fat metabolism;
- decrease in the formation of keto acids;
- increasing the resistance of tissues to the effects of toxic decay products;
- activation of anaerobic glycolysis;
- stimulation and acceleration of reparative processes;
- restoration of the alkaline reserve of blood.
Carnitine chloride does not affect the blood coagulation system. Possesses antihypoxic properties. Mobilizes fat from fat depots. Includes fatty acid metabolic shunt, competitively displacing glucose. Its activity, unlike aerobic glycolysis, is not limited by oxygen, and therefore the drug is effective in conditions of acute hypoxia (including the brain) and other critical conditions.
After intravenous administration, carnitine chloride is almost completely eliminated from the blood after 3 hours. Easily penetrates into the myocardium and liver, more slowly into muscle tissue. It is excreted mainly in the form of acyl esters by the kidneys.
Indications for use
- ischemic stroke (in the acute and recovery periods);
- transient disorders of cerebral circulation;
- brain damage (traumatic and toxic).
- pregnancy and lactation;
- individual intolerance to any component of the drug.
Instructions for the use of Carnitine: method and dosage
The agent is injected intravenously drip, slowly (no more than 60 drops / min).
Before administration, 5-10 ml of the solution should be diluted in a 0.9% sodium chloride solution with a volume of 200 ml.
Recommended dosage regimen:
- acute disorders of cerebral circulation: the first 3 days - 1000 mg per day, then 7 days - 500 mg; after 10-12 days a second course should be carried out - 500 mg per day for 3-5 days;
- subacute and recovery periods of stroke, dyscirculatory encephalopathy, toxic / traumatic brain lesions: 500-1000 mg per day for a course of 3-5 days. If necessary, a second course can be prescribed in 12-14 days.
Possible side reactions: muscle weakness in patients with uremia, allergic reactions.
With a rapid introduction (from 80 drops / min), the appearance of pain along the vein can be observed (with a decrease in the rate of administration, pain passes).
There are no data on cases of overdose.
There is no information.
Application during pregnancy and lactation
According to the instructions, Carnitine is not prescribed during pregnancy / lactation (due to lack of data).
With the combined use of glucocorticosteroids, there may be an accumulation of carnitine chloride in tissues (except for the liver).
When used with other anabolic agents, the effect of Carnitine is enhanced.
Carnitine analogues are: Glutamic acid, Epilapton, Carnitine chloride.
Terms and conditions of storage
Store in a place protected from light at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Carnitine
Reviews of Carnitine are few, due to its absence in pharmacies. Carnitine chloride injection solution is characterized as an effective drug that has a positive effect on the state of the body in patients after a stroke.
The price of Carnitine in pharmacies
The price of Carnitine is unknown as it is not available in pharmacies. The price for analogs is:
- Carnitine chloride (injection solution, 10 ampoules of 5 ml each) - 225–336 rubles;
- Glutamic acid (tablets of 250 mg, 10 tablets in a package) - 25–48 rubles.
Carnitine: prices in online pharmacies
ARNEBIA CARNITIN + VITAMIN C, effervescent tablets, 20 pcs in a plastic tube
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!