Laennec
Laennek: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Use in the elderly
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Laennec
ATX code: A05BA
Active ingredient: Human placenta hydrolyzate (Human placenta extract)
Producer: JAPAN BIOPRODUCTS INDUSTRY (Japan)
Description and photo update: 2018-23-10
Prices in pharmacies: from 10,850 rubles.
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Laennec is a hepatoprotective drug with an immunomodulatory effect.
Release form and composition
Laennek's dosage form is a solution for injection: transparent, from brown to light yellow, with a characteristic odor (in dark glass ampoules, 2 ml each, in a cardboard box of 10 or 50 ampoules).
Composition of 1 ml solution:
- active substance: human placenta hydrolyzate - 0.056 g;
- auxiliary components: hydrochloric acid or sodium hydroxide (pH corrector), water for injection.
Pharmacological properties
Pharmacodynamics
By stimulating humoral immunity and increasing the functional activity of natural killer cells and phagocytes, Laennek exhibits its immunomodulatory properties. The drug increases the bactericidal activity of peripheral blood leukocytes, which is manifested in their ability to destroy the captured pathogen.
The actions of the drug Laennek, due to the active substance included in its composition:
- activation of the metabolic and supervisory function of skin cells;
- increased tissue respiration activity;
- reducing the deposition of lipids and cholesterol in the liver cells;
- manifestation of detoxification properties;
- stimulating the regeneration of hepatocytes;
- a decrease in the intensity of the development of connective tissue in the liver;
- activation of metabolism in the liver.
Indications for use
- chronic recurrent herpes, atopic dermatitis of moderate and severe course, including complicated (as part of complex treatment);
- chronic liver diseases: steatohepatitis of alcoholic, metabolic and mixed origin (as monotherapy).
Contraindications
Absolute:
- childhood;
- pregnancy;
- period of breastfeeding;
- individual intolerance to the components that make up the drug.
Relative (diseases / conditions in the presence of which the appointment of Laennec requires caution):
- polyvalent drug allergy;
- elderly age.
Instructions for the use of Laennek: method and dosage
The solution is administered intravenously (IV) drip or intramuscularly (IM).
Dosing regimen:
- chronic recurrent herpes and atopic dermatitis: 0.01 L of the drug is injected intravenously through the cubital vein into 0.25–0.5 L of saline or 5% dextrose solution for 1.5–2 hours. The frequency of injections is 3 once every 7 days, observing the interval between injections of 2 days. Duration of therapy - 10 injections;
- chronic liver disease: i.m., 0.002 l of the drug per day. Depending on the severity of the pathology, it is possible to increase the frequency of injections by 2–3 times (up to 0.006 l per day). Also, the drug can be injected intravenously through the cubital vein daily at 0.01 L Laennec in 0.25–0.5 L saline or 5% dextrose solution for 1.5–2 hours. Treatment duration - 14–21 days …
Side effects
During the period of Laennec's use, allergic reactions may develop, including anaphylactic shock, soreness and numbness at the injection site, gynecomastia.
Overdose
There are no data on Laennec's overdose.
special instructions
Before using Laennec, it is important to consult with your doctor.
Influence on the ability to drive vehicles and complex mechanisms
Taking the drug has no effect on a person's ability to drive vehicles and work with complex mechanisms.
Application during pregnancy and lactation
According to the instructions, Laennec is contraindicated for use during pregnancy and lactation.
Pediatric use
Studies on the safety of using the drug in children have not been conducted. The use of Laennec in childhood is contraindicated.
Use in the elderly
Due to the fact that physiological functions in elderly patients deteriorate, the use of Laennec in patients of this age category should be carried out under close supervision.
Drug interactions
The activity of Laennec when mixed with other agents that are strong bases (pH> 8.5) decreases as a result of pharmaceutical interactions.
There is no information about any other clinical drug interactions.
Analogs
There are no direct analogues of Laennek, but there are drugs with a similar mechanism of action, among them Darsil, Sirepar, Phosphogliv, Galstena, Hepatosan.
Terms and conditions of storage
Store in a place protected from light and moisture at a temperature of 18 to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Laennek
According to reviews, Laennec is an effective and efficient drug that rarely causes side effects. Among the disadvantages, the high cost of the drug is noted.
The price of Laennek in pharmacies
The approximate price of Laennec solution for injection (10 ampoules in a cardboard box) is 12,100 rubles.
Laennec: prices in online pharmacies
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Drug name Price Pharmacy |
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Laennek solution for intravenous and intramuscular injection 2 ml 10 pcs. RUB 10850 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
