Infagel
Infagel: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Infagel
ATX code: L03AB04
Active ingredient: Interferon alfa-2a (Interferon alfa-2a)
Manufacturer: Vector-Medica CJSC, Russia
Description and photo update: 2019-07-08
Prices in pharmacies: from 101 rubles.
Buy
Infagel is an external agent of a wide spectrum of antiviral, immunomodulatory and antitumor activity, which has a bacteriostatic and anti-inflammatory effect.
Release form and composition
Dosage form - gel for local and external use: a homogeneous mass, white with a grayish tint or white, delamination of the contents is permissible, which is removed by shaking (2, 3, 5 or 10 g in aluminum tubes, 1 tube in a cardboard box; 2, 3, 5 or 10 g in vials, 1 bottle in a cardboard box).
The 1000 mg gel contains:
- Active substance: recombinant human interferon alpha-2b - 10,000 IU (international units);
- Auxiliary components: polyvinyl alcohol - from 17.5 mg, aluminum hydroxide - 57.8 mg, purified water - up to 1000 mg.
Pharmacological properties
Pharmacodynamics
Human recombinant interferon alpha-2b interacts with specific sites that are located on the surface of infected cells, thereby triggering the mechanism of inhibition of viral protein replication and promoting the synthesis of a large number of protein kinases. The result is the destruction of the cellular RNA of the virus and directly the host cell.
Along with an indirect antiviral effect, the drug enhances immunity by activating natural killer cells and enhancing the phagocytic effect of macrophages.
Infagel also has an antitumor and radioprotective effect and affects a number of processes in the body, including the functionality of the central nervous system.
Pharmacokinetics
The gel is intended for topical external use, so the systemic absorption of interferon is very low.
Indications for use
- Treatment of herpetic lesions of mucous membranes and skin: herpes simplex and herpes zoster, recurrent herpes of the face and genitals, herpetic stomatitis, gingivitis;
- Prevention of acute respiratory viral infections (ARVI) and influenza in adults after contact with carriers.
Contraindications
The use of Infagel is contraindicated in allergic diseases in the acute phase.
Instructions for the use of Infagel: method and dosage
The gel is applied externally.
Recommended dosage regimen:
- Treatment of herpetic lesions: on the affected areas of mucous membranes and skin with a thin layer, which is dried for 10-15 minutes until a protective film is formed, the gel is applied 2 times a day with an interval of 12 hours. Duration of therapy - 3-5 days or until complete cure of violations of the integrity of the mucous membranes and skin;
- Prevention of ARVI and influenza (periods of rising incidence): the gel is applied to the mucous membrane of the nasal passages 2 times a day with an interval of 12 hours. The drug is used daily during the first and third weeks of the prophylactic course, in the second week they take a break.
Side effects
When using Infagel, no side effects were noted.
Overdose
Due to the low systemic absorption of Infagel, an overdose of the drug is almost impossible.
special instructions
The protective film formed during the application of the gel on the mucous membranes or the skin does not contaminate clothes, does not smudge and lasts for 12 hours.
According to the instructions, Infagel activates the first line of immune defense in the nasal mucous membranes, its use for prophylaxis in accordance with the recommendations significantly reduces the risk of infection.
Application during pregnancy and lactation
The drug can be used during pregnancy and breastfeeding, if indicated. It is recommended to consult a doctor before using the gel.
Pediatric use
For the treatment of children, Infagel can be used, however, before using the drug, it is recommended to consult with a pediatrician.
Drug interactions
For the treatment of viral and infectious-inflammatory diseases, the gel can be used in combination with glucocorticoids, antibacterial and antiviral drugs, interferon inducers.
Analogs
Infagel's analogs are: Viferon, Gerpevir, Zovirax, Diaferon, Atsik.
Terms and conditions of storage
Store out of the reach of children and isolated from light at a relative humidity of 60% to 80% and a temperature of 0-10 ° C.
Shelf life is 2 years.
Transport using all types of covered transport at a temperature of 0-10 ° C.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Infagel
The drug was highly appreciated by patients. According to reviews, Infagel is effective in 99% of cases in the treatment of herpes. Patients note that when using the gel, the external manifestations of herpes infection quickly disappear and the skin is completely restored.
When using the drug for prophylactic purposes (to prevent SARS and influenza), positive reviews were also received.
Some doctors express a rather controversial opinion about the impossibility of using Infagel for children under 2 years old, therefore, before prescribing the drug to young children, it is imperative to consult a specialist.
Price for Infagel in pharmacies
Infagel in tubes of 3 g can be bought in pharmacies at a price of 111 rubles. The price of Infagel in tubes of 5 g is 151 rubles and more.
Infagel: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Infagel 10000 IU / g gel for local and external use 3 g 1 pc. RUB 101 Buy |
|
Infagel gel for local and outdoor. approx. 10 thousand. IU / g 3g 132 RUB Buy |
|
Infagel 10000 IU / g gel for local and external use 5 g 1 pc. 153 r Buy |
|
Infagel gel for places. and outside. apply. 10000 IU / g tube 5g 184 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
