Terbix - Instructions For The Use Of Spray And Cream, Price, Reviews, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Terbix

Terbix: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. For violations of liver function
13. 13. Drug interactions
14. 14. Analogs
15. 15. Terms and conditions of storage
16. 16. Terms of dispensing from pharmacies
17. 17. Reviews
18. 18. Price in pharmacies

Latin name: Terbix

ATX code: D01AE15

Active ingredient: terbinafine (Terbinafine)

Manufacturer: Altayvitamins (Russia)

Description and photo update: 28.11.2018

Prices in pharmacies: from 124 rubles.

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Terbix is an antifungal drug for external use.

Release form and composition

Terbix dosage forms:

• spray for external use 1%: colorless liquid with a transparent structure, slight opalescence is allowed (30 g each in a glass or aluminum aerosol can with a mechanical pump, 1 can in a cardboard box);
• cream for external use 1%: a mass of white or white with a yellow tint, has a weak specific odor (10 g each in aluminum tubes, in a cardboard box 1 tube).

Each pack also contains instructions for using Terbix.

1 bottle contains:

• active substance: terbinafine hydrochloride - 0.3 g;
• auxiliary components: isopropyl alcohol, polyethylene oxide 400, polysorbate 60, 1,2-propylene glycol, purified water.

1 tube contains:

• active substance: terbinafine hydrochloride - 0.1 g;
• auxiliary components: benzyl alcohol, stearyl alcohol, cetyl alcohol, sodium hydroxide, polysorbate 60, sorbitan stearate, cetyl palmitate, isopropyl myristate, purified water.

Pharmacological properties

Pharmacodynamics

Terbix is a drug for external use with a wide range of antifungal activity. Terbinafine has the specific property of disrupting the early sterol biosynthesis that occurs in fungi. This leads to a deficiency of ergosterol, accumulation of squalene inside the cells and death of the fungal cell. The mechanism of action of terbinafine is due to the inhibition of the enzyme squalene epoxidase, which is located on the cell membrane of the fungus.

In insignificant concentrations, terbinafine exhibits a fungicidal effect against molds (mainly Candida albicans) and dimorphic fungi Pityrosporum orbiculare, dermatophytes - Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton cannabisum, Trichophyton violaceton, Trichophyton cannaceum, Trichophyton tons Depending on the type of yeast fungi, activity against them can be fungicidal or fungistatic in nature.

Terbinafine does not affect the cytochrome P _{450 system} in humans, the metabolism of hormones or other drugs.

Pharmacokinetics

The systemic effect of terbinafine when applied externally is insignificant, its absorption is less than 5%.

Indications for use

The use of all dosage forms of Terbix is indicated for the prevention and treatment of the following diseases:

• fungal lesions of the smooth skin of the body, feet and groin caused by dermatophytes of the genus Trichophyton (including Trichophyton rubrum, Trichophyton verrucosum, Trichophyton mentagrophytes, Trichophyton violaceum), Epidermophyton floccosum, Microsporum canis;
• tinea versicolor caused by Pityrosporum orbiculare or Malassezia furfur.

In addition, the cream is prescribed for yeast infections of the skin, including diaper rash, caused by the genus Candida (including Candida albicans).

Contraindications

The use of Terbix is contraindicated in persons with established hypersensitivity to the components of the drug.

In addition, it is not recommended to use a spray and cream for the treatment of children under 12 years of age.

Terbinafine should be prescribed with caution in patients with hepatic and / or renal insufficiency, chronic alcoholism, inhibition of bone marrow hematopoiesis, occlusive pathologies of the vessels of the extremities, neoplasms, metabolic diseases.

The use of Terbix cream or spray during the gestation period is possible only for strict indications, when the expected effect of therapy for the mother outweighs the risk for the fetus.

Terbiks, instructions for use: method and dosage

Spray for external use 1%

Spray Terbix is applied externally, by spraying on the skin of the affected areas of the body in an amount sufficient to moisturize it, capturing the adjacent areas.

Before applying the drug, the affected area must be thoroughly cleaned and dried.

Recommended dosage for adults:

• dermatomycosis of the trunk, legs, feet: once a day;
• tinea versicolor: 2 times a day.

The duration of the course of treatment is 7 days.

Cream for external use 1%

Terbix cream is applied externally, by applying a thin layer to the skin of the affected area of the body, capturing the adjacent areas, after which it is lightly rubbed.

Before the procedure, the affected area must be thoroughly cleaned and dried. When treating infections located under the mammary glands, in the interdigital spaces, in the groin area or between the buttocks, which are accompanied by diaper rash, it is recommended to cover the area of application of the cream with a gauze cloth, especially at night.

Recommended dosage for patients over 12 years of age:

• dermatomycosis of the trunk, legs, feet: 1 time per day, course duration 7 days;
• candidiasis of the skin: 1-2 times a day for 7-14 days;
• tinea versicolor: 1–2 times a day for 14 days.

The therapeutic effect of Terbix usually occurs after several days of treatment and is accompanied by a noticeable decrease in the severity of the clinical manifestations of pathogenic lesions.

Irregular procedures or early discontinuation of therapy increases the risk of re-infection.

If, after 7-14 days of using the cream or spray, there are no signs of improvement, additional studies are required to clarify the diagnosis.

Side effects

Against the background of the use of Terbix, redness, an itching and / or burning sensation in the places where the drug is applied, and the development of allergic reactions may occur.

Overdose

Symptoms: against the background of accidental ingestion of the drug inside - epigastric pain, nausea, headache, dizziness.

Treatment: taking activated carbon, carrying out symptomatic supportive therapy as needed.

special instructions

Do not allow Terbix to get into the eyes. In case of accidental contact with a spray or cream in the eyes, rinse them immediately with running water. If persistent eye irritation develops, consult a doctor.

In case of accidental inhalation of a high dose of spray and the appearance of undesirable phenomena, you should consult your doctor.

The development of allergic reactions is the basis for immediate discontinuation of the drug.

It should be borne in mind that the spray contains alcohol and may cause irritation when applied to damaged skin.

Application during pregnancy and lactation

Since the clinical experience of using Terbix is positive, but limited, the appointment of a cream or spray is possible only on strict indications in cases where the expected therapeutic effect for the mother outweighs the risk for the fetus.

Due to the low degree of absorption of terbinafine through the skin, it is unlikely that the drug will adversely affect the infant if it is necessary to use a spray or cream during breastfeeding.

Pediatric use

It is not recommended to prescribe Terbix for the treatment of children under 12 years of age due to the lack of sufficient clinical experience.

With impaired renal function

It is recommended to use Terbix with caution to treat patients with renal insufficiency.

For violations of liver function

It is recommended to use Terbix with caution for the treatment of patients with hepatic impairment.

Drug interactions

The interaction of the spray or cream Terbix with the simultaneous use of other drugs has not been established.

Analogs

Terbiks analogs are Terbinafin, Lamisil, Thermikon, Fungoterbin, Exifin, Binafin, etc.

Terms and conditions of storage

Keep out of the reach of children.

Store at temperatures up to 30 ° C, do not freeze.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Terbix

The few reviews about Terbix do not allow an assessment of the effectiveness of the drug.

Some patients report negative experiences with the spray when treating toenail fungus and the need for another antifungal agent.

Price for Terbix in pharmacies

The price for Terbix for a package containing 1 aerosol canister can range from 196 rubles.

Terbix: prices in online pharmacies

Drug name Price Pharmacy

Terbix 10 mg / g spray for external use 30 g 1 pc. 124 RUB Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!