IZZHOGOFF
IZZHOGOFF: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: IZZHOGOFF
ATX code: A02AX
Active ingredient: calcium carbonate (Calcium carbonate) + magnesium carbonate (Magnesium carbonate)
Manufacturer: CJSC "EVALAR" (Russia)
Description and photo update: 2020-22-07
Prices in pharmacies: from 186 rubles.
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IZHOGOFF is an antacid agent.
Release form and composition
The drug is produced in the form of chewable tablets (mint): biconvex, oval, almost white or white, with a mint smell (12 pcs. In a blister strip; in a cardboard box 1, 2 or 4 packages and instructions for use of IZHOGOFF).
1 tablet contains:
- active substances: magnesium carbonate (basic magnesium carbonate) - 80 mg, calcium carbonate - 680 mg;
- additional components: potato starch, sorbitol, maltodextrin, pregelatinized corn starch, natural flavoring "Mint", magnesium stearate, sodium saccharin, talc.
Pharmacological properties
Pharmacodynamics
IZHOGOFF is a local antacid drug. The active components of the drug are magnesium carbonate and calcium carbonate. In the presence of excess hydrochloric acid in the gastric juice, they lead to a quick and long-term neutralization of the latter, thereby protecting the gastric mucosa. The high calcium content in the preparation and good solubility help to achieve a positive effect within 3-5 minutes.
Pharmacokinetics
The result of the interaction of the antacid agent with gastric juice in the stomach is the formation of soluble magnesium and calcium salts. The degree of absorption from these compounds of calcium and magnesium depends on the dose of the drug. The maximum absorption for calcium and magnesium is 10% and 15–20%, respectively. A small amount of absorbed above elements are eliminated by the kidneys. From soluble salts in the intestine, insoluble compounds are formed, which are subsequently excreted with feces.
Indications for use
IZHOGOFF is recommended for use in the development of the following symptoms caused by reflux esophagitis and increased acidity of gastric juice:
- a feeling of overflow or heaviness in the epigastric region;
- sour belching;
- heartburn;
- dyspeptic symptoms, including those associated with taking medications, errors in diet, abuse of nicotine, alcohol, coffee;
- recurrent pain in the stomach.
Also IZHOGOFF is used in the treatment of dyspepsia in pregnant women.
Contraindications
- hypophosphatemia;
- hypercalcemia;
- nephrocalcinosis;
- severe renal impairment;
- age up to 12 years;
- rare hereditary fructose intolerance;
- hypersensitivity to any component of the product.
IZZHOGOFF, instructions for use: method and dosage
IZHOGOFF chewable tablets are taken by chewing or holding in the mouth until completely dissolved.
In the absence of other doctor's recommendations, in the event of the appearance of the corresponding symptoms, the drug should be taken in a dose of 1-2 tablets. If necessary, you can re-take the drug after 2 hours.
The maximum daily dose should not exceed 11 tablets.
Side effects
When using IZHOGOFF in the recommended doses, it is usually well tolerated. However, sometimes during treatment, the development of allergic reactions may occur, including Quincke's edema, rash, anaphylactic reactions.
Overdose
A long course of therapy in high doses against the background of impaired renal function can lead to the development of such phenomena as hypercalcemia, hypermagnesemia, alkalosis, accompanied by muscle weakness, nausea, and vomiting. In this condition, it is required to cancel the drug and urgently consult a doctor.
special instructions
If the antacid is used in high doses, the risk of kidney calculus is exacerbated.
IZHOGOFF can be used in patients with diabetes mellitus; 1 tablet contains 369.5 mg of sorbitol.
If after taking the drug there is no improvement in the condition, you need to seek the advice of a specialist.
Influence on the ability to drive vehicles and complex mechanisms
IZZHOGOFF does not adversely affect the ability to drive vehicles and perform other potentially hazardous activities.
Application during pregnancy and lactation
When pregnant / lactating women take IZHOGOFF chewable tablets in recommended doses, the antacid preparation does not pose a threat to the health of the mother and fetus or child.
Pediatric use
Treatment with the drug is contraindicated in children under 12 years of age.
With impaired renal function
With impaired renal function, the plasma content of calcium and magnesium may increase. IZHOGOFF is not used in patients with severe renal failure.
When using the drug in persons with functional impairment of the kidneys, it is required to regularly monitor serum levels of phosphorus, magnesium and calcium. Patients in this group should not take high doses of IZHOGOFF for a long time.
Drug interactions
With the simultaneous administration of an antacid drug with other drugs, the following reactions are possible:
- fluoroquinolones, iron preparations, tetracycline antibiotics, levothyroxine, cardiac glycosides, fluorides, phosphates: absorption of these agents decreases;
- thiazide diuretics: interaction may develop, it is required to regularly determine the serum calcium concentration;
- other drugs: the rate and degree of absorption of all drugs taken simultaneously decreases due to changes in the acidity of gastric juice; it is recommended to take any therapy 1–2 hours before or after using the antacid.
Analogs
Analogs of IZHOGOFF are Almagel, Ajiflux, Gastal Likvo, Gastal, Ramni, Gattart, Gastracid, Gaviscon, Maalox, Rennie, Fosfalugel, etc.
Terms and conditions of storage
Store in places inaccessible to children, at a temperature not exceeding 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about IZZHOGOFF
Reviews about IZZHOGOFF are mostly positive. Patients note the mild and rapid action of the drug in relieving heartburn, sour belching, severity and discomfort in the epigastric region, and dyspeptic symptoms. The advantages of the drug include its low cost, the possibility of taking it during pregnancy and lactation, as well as in patients with diabetes.
Sometimes there are complaints about the short-term or insufficient therapeutic effect of IZHOGOFF.
Price for IZHOGOFF in pharmacies
Approximate price for IZHOGOFF in the form of chewable mint tablets (680 mg + 80 mg) for 24 pcs. in the package is from 220 to 270 rubles.
IZZHOGOFF: prices in online pharmacies
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Drug name Price Pharmacy |
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Izgoff 680 mg + 80 mg chewable tablets mint flavor 24 pcs. RUB 186 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
