Dicetel - Instructions For Use, Price, Reviews, Analogs Of Tablets

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Dicetel

Dicetel: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Dicetel

ATX code: A03AX04

Active ingredient: pinaverium bromide (pinaverium bromide)

Producer: Abbott Healthcare SAS (France)

Description and photo update: 2019-09-09

Prices in pharmacies: from 366 rubles.

Buy

Dicetel is an antispasmodic drug with m-anticholinergic and myotropic action.

Release form and composition

Dosage form - film-coated tablets: round, orange, on each of the convex sides there is an engraving: on one - the letter S above the triangular icon, on the other - the number 50 or 100, corresponding to the content of the active substance in the tablet (20 pcs. in blisters, in a cardboard box 1 blister and instructions for use of Dicetel).

The active substance is pinaveria bromide, in 1 tablet - 50 or 100 mg.

Auxiliary components: magnesium stearate, colloidal silicon dioxide, lactose monohydrate, microcrystalline cellulose, pregelatinized starch, talc.

The composition of the film shell: butyl methacrylate copolymer, sodium lauryl sulfate, talc, stearic acid, dry sepispers 3203 (microcrystalline cellulose (E460), hypromellose (E464), sunset yellow dye (aluminum lacquer) (E110), titanium dioxide (E171)).

Pharmacological properties

Pharmacodynamics

Dicetel is an antispasmodic agent with a selective effect on the gastrointestinal tract. Inhibits the flow of calcium into the cells of the intestinal smooth muscles.

In animal studies, it was found that pinaverium bromide reduces the effects of stimulating sensitive neurons. It has no anticholinergic effect, it does not affect the cardiovascular system.

Pharmacokinetics

After oral administration, pinaverium bromide is rapidly absorbed and reaches its maximum plasma concentration in 60 minutes. The substance has a high ability of binding to plasma proteins (approximately 95-96%).

Pinaverium bromide is actively metabolized in the liver. The half-life is 1.5 hours. The absolute bioavailability is very low (up to 1%). It is excreted from the body mainly with feces.

Indications for use

The use of Dicetel is indicated for symptomatic therapy:

• Discomfort caused by a functional disorder of the intestines, pain, impaired motility of the gastrointestinal tract (GIT);
• Pain associated with a functional disorder of the biliary tract.

In addition, Dicetel is prescribed in preparation for an X-ray examination of the gastrointestinal tract using barium sulfate.

Contraindications

• Glucose-galactose malabsorption syndrome, galactose intolerance, lactase deficiency;
• Age under 18;
• Breastfeeding period;
• Hypersensitivity to drug components.

With caution, Dicetel tablets are prescribed during pregnancy, especially in the third trimester, since there is a risk of neurological disorders in the infant. Use is allowed if the intended benefit of the drug to the mother outweighs the potential harm to the fetus.

Dicetel, instructions for use: method and dosage

The tablets are taken orally during meals, swallowing whole (without dissolving or chewing), and washed down with plenty of water in order to prevent contact of the active substance with the esophageal mucosa.

Recommended daily dosage of Dicetel:

• Film-coated tablets, 50 mg each: 1 pc. 3 times or 2 pcs. 2 times a day, in some cases the daily dose may be 6 tablets (2 pcs. 3 times). To prepare for an X-ray examination of the gastrointestinal tract, the patient should take 2 pcs. 2 times a day for 3 days before the procedure;
• Film-coated tablets, 100 mg: 1 pc. 2 times a day, depending on clinical indications, the frequency can be increased up to 3 times a day. Before X-ray examination, the patient is prescribed 1 piece. 2 times a day for 3 days.

Side effects

The use of Dicetel can cause side effects:

• From the digestive system: nausea, abdominal pain, vomiting, diarrhea, dysphagia; non-observance of the recommendations for taking the drug can lead to damage to the esophageal mucosa;
• From the immune system: hypersensitivity reactions;
• From the side of the skin: rash, urticaria, itching, erythema.

Overdose

Main symptoms: gastrointestinal upset, including flatulence and diarrhea.

Therapy: symptomatic. There is no specific antidote.

special instructions

The use of Dicetel should strictly comply with the recommendations for admission, since there is a high probability of damage to the mucous membrane of the esophagus, special attention should be paid to patients with hiatal hernia and / or esophagitis.

Influence on the ability to drive vehicles and complex mechanisms

The effect of Dicetel on the ability to drive vehicles and mechanisms has not been studied.

Application during pregnancy and lactation

• pregnancy: Dicetel can be used with caution after assessing the ratio of the expected benefit to the possible risk, the safety profile has not been studied;
• lactation period: therapy is contraindicated.

Pediatric use

Dicetel is not prescribed to patients under 18 years of age.

Drug interactions

The interaction of pinaverium bromide with oral anticoagulants, hypoglycemic drugs, cardiac glycosides, insulin and heparin has not been identified.

The influence of Dicetel on the results of laboratory tests to determine the level of concentration of drugs was not observed.

With simultaneous use with anticholinergics, it is possible to increase the relief of spasms.

Analogs

Dicetel's analogs are: Bobotik, Bebinos, Vinboron, Disflatil, Duspatalin, Carminativum, Kuplaton, Colikid, Infacol, Meteospazmil, Plantex, Platyphyllin, fennel fruits, caraway seeds, Romazulan, Sub Simplex, Eteruspazmil, Espuzzol.

Terms and conditions of storage

Store in a dark, dry place at temperatures up to 30 ° C. Keep out of the reach of children.

The shelf life is 5 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Dicetel

Reviews about Dicetel are both positive and negative. Some users recommend it as a highly effective drug with good tolerance. In other cases, they indicate an insufficient therapeutic effect of the drug or the development of pronounced side reactions. The cost is most often assessed as high.

Price for Dicetel in pharmacies

The approximate price for Dicetel is 391-536 rubles. (20 tablets of 50 mg each) or 560-757 rubles. (20 tablets of 100 mg).

Dicetel: prices in online pharmacies

Drug name Price Pharmacy

Dicetel 50 mg film-coated tablets 20 pcs. 366 r Buy

Dicetel tablets p.p. 50mg 20 pcs. 542 r Buy

Dicetel 100 mg film-coated tablets 20 pcs. RUB 620 Buy

Dicetel tablets p.p. 100mg 20 pcs. 762 RUB Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!