DioridinVel
DioridinVel: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: DioridinVel
ATX code: C05CA53
Active ingredient: Hesperidin + Diosmin (Hesperidin + Diosmin)
Manufacturer: Velpharm, LLC (Russia)
Description and photo update: 2019-11-07
Prices in pharmacies: from 829 rubles.
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DioridinVel is a venotonic and venoprotective drug.
Release form and composition
Dosage form - film-coated tablets: biconvex, oval, orange-pink, with a risk; at the break, the color of the tablet is from grayish-yellow to light yellow (in a cardboard box 1-10 packs of cell contour with 10 tablets in each of them, or 1 can containing 20, 30 or 60 tablets, and instructions for use of DioridinVel).
Composition of 1 tablet:
- active substances: hesperidin - 50 mg, diosmin - 450 mg;
- auxiliary components: opadry II 32F230011 orange (macrogol 4000, titanium dioxide, lactose monohydrate, hypromellose, iron dye red oxide, iron oxide yellow dye), talc, sodium carboxymethyl starch (primogel, sodium starch glycolate), microcrystalline cellulose, magnesium stearate, gelatin purified water.
Pharmacological properties
Pharmacodynamics
DioridinVel contains a combination of hesperidin with diosmin, which has a venotonic and angioprotective effect.
The drug improves the parameters of venous hemodynamics, increases resistance and lowers capillary permeability, reduces venous distensibility and venous congestion. During its application, changes in such venous plethysmographic parameters as venous emptying time, venous extensibility and venous capacity are noted.
Achievement of the optimal therapeutic effect is observed when taking 1000 mg of the drug.
By reducing the time of venous emptying, the combination of hesperidin + diosmin increases venous tone. In the presence of signs of a pronounced violation of microcirculation, an increase in capillary resistance is observed. This combination is effective in the treatment of chronic pathologies of the veins of the lower extremities and hemorrhoids.
Pharmacokinetics
The drug is mainly excreted through the intestines. Through the kidneys, on average, approximately 14% of the taken dose of the drug is excreted. Its half-life is 11 hours.
DioridinVel undergoes active metabolism, as indicated by the presence of phenolic acids in urine.
Indications for use
- leg fatigue, pain, a feeling of fullness and heaviness in the lower extremities, leg cramps (treatment of symptoms of venous lymphatic insufficiency);
- venous trophic ulcers, trophic changes in the skin and subcutaneous tissue, edema of the legs (treatment of manifestations of venous-lymphatic insufficiency);
- acute and chronic hemorrhoids (symptomatic treatment).
Contraindications
- rare hereditary diseases: glucose-galactose malabsorption syndrome, lactase deficiency or galactose intolerance;
- lactation period;
- individual intolerance to the components of the drug.
DioridinVel, instructions for use: method and dosage
DioridinVela tablets are taken orally at the same time as food.
The dosage of the drug, depending on the indications, is:
- venous lymphatic insufficiency: 2 tablets per day in one or two doses in the morning, afternoon and / or evening. The duration of therapy can be several months, up to 1 year. If the patient develops symptoms again, the doctor may prescribe a second course of treatment;
- acute hemorrhoids: in the first 4 days - 6 tablets per day (3 pcs. in the morning and in the evening), in the next 3 days - 4 tablets per day (2 pcs. in the morning and evening);
- chronic hemorrhoids: 2 tablets per day.
Side effects
Possible side reactions when using DioridinVel tablets:
- central nervous system: rarely (> 0.01% and <0.1%) - general malaise, headache, dizziness;
- digestive system: often (> 1% and 0.1% and <1%) - colitis; the frequency is unknown (it is impossible to determine the frequency of occurrence of adverse events based on the available data) - abdominal pain;
- allergic reactions: rarely - urticaria, pruritus / rash; the frequency is unknown - isolated edema of the eyelids, lips, face, in exceptional cases - angioedema.
The patient should inform the doctor about the development of any side effects and changes in laboratory parameters during the treatment period.
Overdose
There have been no reports of drug overdose.
special instructions
Before starting therapy with DioridinVel, it is recommended to consult a doctor.
In cases of exacerbation of hemorrhoids, the use of the drug does not replace the specific therapy for other anal disorders. The duration of taking the pills should not exceed the recommended course. Patients in whom, after the recommended treatment period, the manifestations of pathology do not disappear, it is necessary to undergo a proctological examination. In this case, the tactics of treatment should be reviewed.
Achieving the maximum therapeutic effect in case of venous circulation disorders is ensured by combining DioridinVel treatment with a balanced (healthy) lifestyle. It is important for patients not to allow prolonged stay on their feet, refrain from long exposure to the sun, and in the presence of excess body weight - to reduce it. Walking is recommended, and in some cases, wearing special stockings that help improve blood circulation.
In the absence of a therapeutic effect or worsening of the condition, the patient should immediately consult a doctor.
Application during pregnancy and lactation
DioridinVel can be prescribed during pregnancy.
During breastfeeding, taking the drug is contraindicated, since there is no data on its excretion into breast milk.
Drug interactions
There are no data on interactions with other drugs. Patients are advised to inform the doctor about all drugs taken in combination with DioridinVel.
Analogs
The analogues of DioridinVel are: Detralex, Flebaven, Detravenol, Stimulven, VENOSMIN, Venolife Duo, Diovenges, Venarus, ANGIORUS, etc.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about DioridinVel
According to a few reviews, DioridinVel is a safe and effective drug that can be used over a long period for the treatment of venous lymphatic insufficiency.
Price for DioridinVel in pharmacies
The approximate price of DioridinVel (60 film-coated tablets in a package) varies from 867 to 1024 rubles.
DioridinVel: prices in online pharmacies
Drug name Price Pharmacy |
Dioridinvel 50 mg + 450 mg tablets 60 pcs. 829 RUB Buy |
Dioridinvel tablets p.p. 50mg + 450mg 60 pcs. 890 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!