Nourished
Vormil: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Vormil
ATX code: P02SA03
Active ingredient: albendazole (albendazolum)
Manufacturer: Unimax Laboratories, XL Laboratories Pvt Limited, Themis Medicare Limited (India / UK)
Description and photo update: 2019-16-08
Vormil is a broad-spectrum anthelmintic drug.
Release form and composition
Dosage forms of Vormil:
- Chewable tablets (3 pcs. In blisters, 1 blister in a cardboard box);
- Suspension for oral administration (10 ml in glass bottles, 1 bottle in a cardboard box).
The composition of 1 tablet Vormil includes:
- Active ingredient: albendazole - 400 mg;
- Auxiliary ingredients: corn starch, microcrystalline cellulose, purified talc, colloidal silicon dioxide, magnesium stearate, sodium starch glycolate, sodium methyl hydroxybenzoate, sodium propyl hydroxybenzoate, mixed fruit essence and aspartame.
10 ml of suspension contains:
- Active ingredient: albendazole - 400 mg;
- Auxiliary components: sodium benzoate, sodium methylhydroxybenzoate, sucrose, sodium propylhydroxybenzoate, polysorbate 80, croscarmellose sodium, erythrosine, glycerol, mixed fruit essence, raspberry essence, purified water.
Pharmacological properties
Pharmacodynamics
Albendazole is effectively used to treat various diseases caused by parasites that cause tissue damage in the intestinal region. Adult helminths, as well as their larvae and eggs, are sensitive to this substance. The anthelmintic effect of albendazole causes tubulin polymerization, which leads to disturbances in the metabolism of helminths and their further death.
Albendazole is active against a wide variety of intestinal and tissue helminths, as well as protozoa. In many cases, it helps to reduce the size or complete disappearance of the cyst of granular echinococcus.
Pharmacokinetics
When taken orally, albendazole is poorly absorbed from the gastrointestinal tract. The absorption of the active ingredient is significantly increased by taking Vormil along with fatty foods. Albendazole has a first pass effect through the liver, where it is rapidly metabolized. The main metabolite is albendazole sulfate, the pharmacological activity of which is approximately 50% higher than that of albendazole itself.
The half-life is 8.5 hours. Albendazole is excreted mainly in urine and bile. If the drug is prescribed in high doses for a long time to treat cysts, the elimination of metabolites from the cysts may continue for several weeks.
Indications for use
According to the instructions, Vormil is prescribed for parasitic invasions: ascariasis, ankylostomiasis, necatorosis, capillarosis, enterobiasis, teniasis, hymenolepiasis, cutaneous migratory larvae, strongyloidosis, trichinosis, gnatostomiasis, clonorchiasis, giardiasis in children, toxocariasis.
Contraindications
- Pregravid period;
- Pregnancy and lactation;
- Children under 2 years old;
- Hypersensitivity to drug components.
Instructions for use of Vormil: method and dosage
The doctor determines the regimen of the drug individually. Before swallowing the tablet, Vormil must be chewed.
For trichinosis, ascariasis, ankylostomiasis, noncatorosis and enterobiasis, adults and children from 2 years of age are prescribed 1 tablet or 10 ml of suspension (400 mg) per day for a course of 3-5 days; with teniasis, hymenolepiasis and strongyloidiasis in the same dosage - 3 days. In the case of confirmed hymenolepiasis, the course of therapy should be repeated after 21 days.
For the treatment of clonorchiasis, opisthorchiasis, mixed invasion of Opisthorchis viverrini and Chlonorchis sinensis, adults and children from 2 years old Vormil take 400 mg for 3 days, the frequency of administration is 2 times a day.
Children 2-12 years old with the treatment of giardiasis, the drug is prescribed 1 tablet or 10 ml of suspension per day. Duration of admission is 5 days.
In case of systemic helminthic invasion, the dose of Vormil is determined by the patient's body weight, the type of parasite and the severity of the disease.
In the treatment of cystic echinococcosis in patients weighing 60 kg or more, the drug is prescribed 1 tablet or 10 ml of suspension 2 times a day. The duration of therapy is 28 days. With a body weight of less than 60 kg, Vormil is prescribed at the rate of 15 mg / kg per day, divided into 2 doses. The maximum daily dose is 800 mg. If necessary, 3 treatment cycles are carried out with an interval of 14 days. When treating alveolar echinococcosis, the drug is prescribed according to the same scheme. Longer use of the drug is possible (several months or years).
With cutaneous larva migrans, Vormil should be taken 1-3 days, 1 tablet or 10 ml of suspension 1 time per day.
For the treatment of neurocysticercosis, patients weighing over 60 kg are prescribed 400 mg 2 times a day, with a weight of up to 60 kg - 15 mg / kg per day, divided into 2 doses. The maximum daily dose is 800 mg. The duration of the course, depending on the results, can vary from 7 to 30 days. After 1-2 weeks, the course can be repeated.
With capillariasis, children and adults are prescribed a course of 10 days, 1 tablet or 10 ml of suspension per day. When treating gnatostomiasis, Vormil is taken in the same dose, the duration of the course can be increased to 20 days.
Side effects
During therapy, the development of disorders from some body systems is possible:
- Digestive system: nausea, dry mouth, vomiting, heartburn, stomatitis, flatulence, diarrhea, constipation, abdominal pain;
- Nervous system: disorientation, hallucinations, dizziness, seizures, headache, insomnia or drowsiness, confusion;
- Blood system: leukopenia, pancytopenia;
- Organ of vision: decreased visual acuity;
- Hypersensitivity reactions: dermatitis, urticaria, pemphigus, pruritus, fever.
Overdose
The most important symptoms indicating an overdose of Vormil are speech disorders, blurred vision, fainting, nausea, vomiting, dizziness, drowsiness.
As a treatment, gastric lavage, intake of enterosorbents and other symptomatic therapy are prescribed.
special instructions
If the laboratory parameters are exceeded by more than 2 times from the upper limit, the use of Vormil should be interrupted until they are completely normalized.
At the beginning of therapy and every 14 days of a 28-day course of treatment, it is necessary to monitor the level of leukocytes. With the development of leukopenia, Vormil's reception can be continued in cases where the disease does not progress.
Drug interactions
An increase in the concentration of the active substance is possible with the simultaneous use of Vormil with praziquantel, dexamethasone and cimetidine.
Analogs
Vormil's analogues are: Aldazol, Vermox, Zentel, Nemozol, Medizol, Farmoks.
Terms and conditions of storage
Store in a dark, dry place out of reach of children at temperatures up to 25 ° C.
The shelf life of the drug in the form of tablets is 3 years, the suspension is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Vormila
According to reviews, Vormil is a fairly popular drug, so reports of its high effectiveness are frequent. Treatment with them usually gives good results, which is confirmed by reports of both doctors and patients. Often, Vormil is prescribed to the whole family, and the test results prove that it is possible to get rid of the problems quickly enough.
However, some parasitologists, noting the high efficacy of the drug in relation to most parasites, simultaneously note a decrease in immunity and the development of other adverse reactions. Vormil is suitable for use in children, but it should only be taken after consulting a specialist and passing all the necessary tests.
The price of Vormil in pharmacies
At the moment, the price of Vormil remains unknown, since the drug is not available for sale.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
