Vimovo
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Analogs
- 4. Indications for use
- 5. Contraindications
- 6. Method of application
- 7. Drug interactions
- 8. Side effects
- 9. Storage conditions
Vimovo is a combined drug related to non-steroidal anti-inflammatory drugs and is a proton pump inhibitor.
Pharmacological action Vimovo
The shell of Vimovo tablets contains esomeprazole magnesium, which is released immediately when it enters the stomach and affects the decrease in the secretion of hydrochloric acid, and the core of the tablet contains naproxen, which is released slowly and has antipyretic and analgesic effects.
Release form Vimovo
According to the instructions, Vimovo is produced in the form of yellow oval tablets, coated with an enteric film, with a black inscription "500/20" on one side, in plastic bottles with a screw cap, with a first opening control.
One Vimovo tablet contains 500 mg of naproxen and 22.3 mg of esomeprazole magnesium trihydrate, as well as:
- 50 mcg carnauba wax;
- 35 mg of hypromellose 3 mPas77;
- 2.69 mg glycerol monostearate 40-55;
- 10.85 mg hypromellose 6 mPas;
- 680 μg hypromellose 50 mPas;
- 580 μg iron oxide yellow (E172);
- 22 mg croscarmellose sodium;
- 2.62 mg colloidal silicon dioxide;
- 1.38 mg magnesium stearate;
- 5.85 mg macrogol 8000;
- 20 μg methyl parahydroxybenzoate (E218);
- 4.55 mg polysorbate 80;
- 11 mg of povidone K90;
- 6.3 mg polydextrose (E1200);
- 10 μg propyl parahydroxybenzoate (E216);
- 54.6 mg of suspension 30%;
- 8.18 mg triethyl citrate;
- 13.26 mg titanium dioxide.
The tablet shell contains black ink - qs, which consists of 22% black iron oxide, 7% hypromellose 6 mPas, 10% propylene glycol, 12% isopropanol and 49% purified water.
Analogs of Vimovo
There are no analogues of Vimovo tablets according to the active substance. By the mechanism of action and belonging to the same pharmacological group, Vimovo's analogues include:
- Advil;
- Artrum;
- Algezir Ultra;
- ArtroCam;
- Bonifen;
- Quickcaps;
- Dexalgin 25;
- Ibuprofen;
- Ibufen;
- Ketoprofen;
- MIG 400;
- Naproxen-ICN;
- Nurofen asset;
- Nurofen UltraCap;
- OKI;
- Rakstan-Sanovel;
- Teraflex Advance;
- Faspik;
- Flexen;
- Hayrumat.
Indications for Vimovo's use
According to the instructions, Vimovo is used to relieve symptoms caused by rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, and is also prescribed to patients at risk of developing duodenal and gastric ulcers associated with the use of non-steroidal anti-inflammatory drugs.
Contraindications
Vimovo tablets are contraindicated for:
- Severe uncontrolled heart failure;
- Severe liver failure or active liver disease;
- Confirmed hyperkalemia;
- History of urticaria, bronchial asthma and allergic reactions when taking non-steroidal anti-inflammatory drugs;
- Severe renal failure;
- Condition after coronary artery bypass grafting;
- Peptic ulcer of the duodenum or stomach in the acute phase;
- Inflammatory bowel disease in the acute phase;
- Co-administration with Atazanavir and Nelfinavir;
- Hypersensitivity to drug components;
- Gastrointestinal bleeding, cerebral hemorrhage, or other bleeding;
- Hypersensitivity to other substituted benzimidazoles.
Also, the drug is contraindicated during the third trimester of pregnancy and during lactation, as well as in children and adolescents under 18 years of age.
Method of using Vimovo
Vimovo, according to the instructions, is used internally as a whole, without chewing, drinking one tablet twice a day with water half an hour before meals. With caution, Vimovo is prescribed for mild to moderate hepatic and renal failure.
Drug interactions
Vimovo, according to the instructions, is not recommended to be combined with antiretroviral drugs, the drug is used with caution with:
- Acetylsalicylic acid (in small doses);
- Diuretics
- Selective serotonin reuptake inhibitors;
- Corticosteroids;
- ACE inhibitors;
- Lithium preparations;
- Methotrexate;
- Sulfonylurea and hydantoin derivatives;
- Warfarin;
- Beta-blockers;
- Probenecid;
- Drugs whose absorption depends on the pH of the stomach.
Side effects
According to reviews, Vimovo can cause undesirable effects from the gastrointestinal tract, namely: nausea, dyspepsia, stomach pain and vomiting.
Also, according to reviews, Vimovo causes constipation, diarrhea, dizziness, pain in the upper abdomen and peripheral edema.
Storage conditions Vimovo
In accordance with the instructions, Vimovo must be stored out of the reach of children and protected from light, in a dry place, at room temperature up to 30 ° C. The shelf life of the drug, subject to the instructions, is two years.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
