Vertum ENT - Instructions For Use Of The Spray, Reviews, Price, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Vertum ENT

Vertum ENT: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. For violations of liver function
13. 13. Use in the elderly
14. 14. Drug interactions
15. 15. Analogs
16. 16. Terms and conditions of storage
17. 17. Terms of dispensing from pharmacies
18. 18. Reviews
19. 19. Price in pharmacies

Latin name: Vertum LOR

ATX code: A01AD02

Active ingredient: benzydamine (Benzydamine)

Manufacturer: JSC "Vertex" (Russia)

Description and photo update: 2020-25-06

Prices in pharmacies: from 226 rubles.

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Vertum ENT is a topical spray with anti-inflammatory action, used in the treatment of diseases of the mouth and throat of any etiology.

Release form and composition

The drug is produced in the form of a spray for topical application dosed: a clear solution, has no color, has a characteristic menthol odor [in high-density polyethylene bottles, equipped with a pump (dosing device) and a protective cap, 40 ml (235 doses); in a pack of cardboard, instructions for use Vertum ENT, actuator (spray nozzle) and 1 bottle].

Composition of 1 spray dose:

• active ingredient: benzydamine hydrochloride - 0.255 mg;
• additional components: glycerin (glycerol) - 8.5 mg; sodium saccharinate - 0.0408 mg; methylparaben (methyl parahydroxybenzoate) - 0.17 mg; polysorbate-20 - 0.0085 mg; ethyl alcohol 95% - 13.6 mg; natural food flavoring Mint (composition: flavoring + propylene glycol; 1 ml of solution contains less than 0.3 mg of propylene glycol) - 0.051 mg; purified water - up to 0.17 ml.

Pharmacological properties

Pharmacodynamics

Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) belonging to the indazole group. It has anti-inflammatory and local analgesic effects, exhibits antiseptic properties against a wide range of pathogenic microorganisms.

The use of Vertum ENT helps to stabilize the cell membranes and inhibit the synthesis of prostaglandins.

The antibacterial and specific antimicrobial properties of benzydamine are due to its rapid penetration through the membranes of microorganisms, where it damages cellular structures, disrupts metabolic processes and destroys cell lysosomes.

Shows antifungal action against Candida albicans. It causes structural changes in the cell wall of fungi and their metabolic chains, thereby preventing their reproduction. This effect served as the basis for the use of benzydamine for the relief of inflammatory processes in the oral cavity, including those with an infectious etiology.

Pharmacokinetics

Topically applied benzydamine is well absorbed from the mucous membranes of the mouth and throat and penetrates into inflamed tissues. It is contained in blood plasma in a small amount, which is not enough for the manifestation of systemic effects

Excretion of benzydamine is carried out mainly in the urine in the form of conjugation products or metabolites that do not have pharmacological activity.

Indications for use

Vertum ENT is used for symptomatic treatment of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiology):

• candidiasis of the oral mucosa - in combination with other drugs;
• tonsillitis, laryngitis, pharyngitis;
• glossitis, gingivitis, stomatitis (after chemotherapy and radiation therapy, inclusive);
• calculous inflammation of the salivary glands;
• periodontal disease;
• conditions after extraction / treatment of teeth, as well as after trauma and surgery, such as fractures of the jaw or tonsillectomy.

For diseases of an infectious and inflammatory nature that require systemic treatment, spray Vertum ENT is prescribed as part of a combination therapy.

Contraindications

Absolute contraindications to the use of the Vertum ENT spray are children under three years of age, pregnancy, lactation period and established hypersensitivity to benzydamine or one or more auxiliary components of the drug.

The agent should be used with caution in patients with bronchial asthma (including information in the anamnesis), as well as hypersensitivity to acetylsalicylic acid and other NSAIDs.

Vertum ENT, instructions for use: method and dosage

Spray Vertum ENT is applied topically by spraying in the oral cavity. It is recommended to use the product after meals.

One injection, or one dose, corresponds to the introduction of 0.255 mg benzydamine.

Recommended dosage regimen:

• children aged 3 to 6 years: 1 injection for every 4 kg of body weight, but not more than 4 injections (maximum single dose);
• children aged 6 to 12: 4 shots each;
• children over the age of 12 and adults (including elderly patients): 4–8 injections each.

The frequency of application of Vertum ENT is 2–6 times a day.

Directions for use:

1. The cannula (the tube that is part of the spray nozzle) is rotated to either side at an angle of 90 ° towards the bottle.
2. A cannula is inserted into the mouth and directed to inflamed areas in the mouth or throat.
3. Press the dosing pump located on the top of the bottle as many times as the doses need to be administered (one dose of the drug is released with one press of the dosing device). During the injection, you must hold your breath for a few seconds.

The recommended dose of Vertum ENT should not be exceeded.

The duration of the therapeutic course is no more than 7 days. If after this time, drug therapy does not bring results and no improvement is observed, or new symptoms develop, you need to seek the advice of a specialist.

It is recommended to use spray Vertum ENT strictly in accordance with the method of application specified in this instruction, observing the prescribed dosage regimen. If necessary, consult a doctor for advice before using the spray.

Side effects

Adverse events are classified in accordance with the recommendations of the WHO (World Health Organization): very often - more than 1/10; often - more than 1/100, but less than 1/10; infrequently - more than 1/1000, but less than 1/100; rarely - more than 1/10 000, but less than 1/1000; very rarely - less than 1/10 000, including single messages; with an unspecified frequency - it is impossible to establish the incidence of adverse reactions based on the available data.

Adverse reactions from systems and organs observed when using the spray:

• immune system: infrequently - photosensitization; rarely - itching / rash, hypersensitivity reactions; extremely rare - laryngospasm, angioedema; with an unknown frequency - anaphylactic reactions;
• general disorders and reactions at the injection site: rarely - burning and dryness in the oral cavity; with an unknown frequency - a feeling of numbness in the mouth.

The aggravation of any of the above adverse events or the development of new adverse reactions not specified in this instruction must be notified to the attending physician.

Overdose

There is no information on cases of benzydamine overdose.

An overdose of Vertum ENT spray, used in the recommended doses, is unlikely.

In case of unintentional ingestion of the drug, symptoms such as abdominal cramps, vomiting, fever, tachycardia, fear, anxiety, hallucinations, ataxia, convulsions, and respiratory depression may occur.

With the development of intoxication, symptomatic treatment is carried out. The stomach is cleansed by inducing vomiting, or by washing with a gastric tube (the procedure is carried out under the supervision of a physician). The patient needs to provide medical supervision, prescribe supportive therapy, and carry out the necessary hydration. There is no antidote.

special instructions

The use of benzydamine can cause the development of hypersensitivity reactions. When they appear, therapy with the drug is stopped and a specialist is consulted to prescribe the appropriate treatment.

In some patients, the presence of sores in the throat and oral cavity may indicate the development of a more serious pathology. If symptoms persist for three days or more, you should seek medical advice.

Benzydamine is not recommended for use in patients with hypersensitivity to acetylsalicylic acid or other NSAIDs.

Caution requires the use of spray Vertum ENT in patients with bronchial asthma (including a history), since while taking benzydamine, they may develop bronchospasm.

Vertum ENT contains parahydroxybenzoates capable of provoking the development of allergic reactions.

Influence on the ability to drive vehicles and complex mechanisms

Vertum ENT has no effect on the ability to drive vehicles and engage in activities that pose a potential hazard (for example, work with moving mechanisms), which requires a high concentration of attention and speed of psychomotor reactions.

Application during pregnancy and lactation

The use of spray Vertum ENT during the period of gestation and breastfeeding is not recommended.

Pediatric use

Vertum ENT is not prescribed for children under three years old.

With impaired renal function

There are no specific instructions for the use of this NSAID in patients with impaired renal function.

For violations of liver function

There are no special instructions for the use of Vertum ENT for patients with impaired hepatic function.

Use in the elderly

Elderly patients can use Vertum ENT according to the dosage regimen established in this instruction.

Drug interactions

No studies have been conducted on the subject of drug interaction of Vertum ENT with other substances / preparations.

Analogs

Analogs of Vertum ENT are Anhidak, Anhidak forte, Anhidak sept, Bronflex, Benzidamine, Benzidamine-Akrihin, Zvezdochka Lor, Oralsept, Tantum Verde, Tantum Verde forte, Tantum Rose, etc.

Terms and conditions of storage

Store in a place inaccessible to children, at a temperature not exceeding 25 ° C.

The shelf life is 3 years.

The manufacturer is prohibited from using the spray after the expiration date indicated on the package.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Vertum ENT

On the Internet, reviews of Vertum ENT are mostly positive. Users love the large volume of the bottle, which is also available at a very attractive price. Patients believe that the main advantage of the drug is its effectiveness, as well as a pleasant mild taste, which is especially popular with mothers of young children. In addition, the spray does not dry the throat, quickly eliminates unpleasant symptoms, relieving pain and inflammation.

Vertum ENT has a small list of side effects, the development of which has not been reported.

Price for Vertum ENT in pharmacies

The price of Vertum ENT spray dosed for topical use (0.255 mg / dose) in pharmacy chains is 185–306 rubles. for 1 bottle of 40 ml.

Vertum ENT: prices in online pharmacies

Drug name Price Pharmacy

Vertum ENT spray for places. approx 0.255 mg / dose vial 40 ml (with spray nozzle) 226 r Buy

Vertum Lor 0.255 mg / dose spray for topical application, dosed 40 ml 1 pc. 226 r Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!