Validol with glucose
Latin name: Validol with glucose
ATX code: C01EX; C01EB
Active ingredient: Levomenthol solution in menthyl isovalerat; dextrose
Manufacturer: OJSC Uralbiopharm (Russia); Pharmstandard-Leksredstva OJSC (Russia); Lumi LLC (Russia); JSC "PFC Obnovlenie" (Russia)
Description and photo update: 2019-11-07
Prices in pharmacies: from 11 rubles.
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Validol with glucose is a combined coronary dilating drug for the treatment of heart diseases, reflex action.
Release form and composition
The drug is produced in the form of sublingual tablets: flat-cylindrical, round; depending on the manufacturer - white or white with gray blotches, or white with a yellow tinge, with possible gray blotches, with or without a line and bevel, with a specific smell of menthol (6 or 10 pcs. in a blister strip; 1– 5 packs of 6 or 10 pcs., 6, 10 or 20 packs of 10 pcs. In a cardboard box; 10, 20, 30, 40, 50 or 60 pcs. In a polymer can, 1 can in a cardboard box; 5, 10, 20, 50, 100, 200, 400, 500 or 600 blister packs of 10 in a hermetically sealed plastic bag, bags in a cardboard box; 1000 packs of 10 in a cardboard box - for a hospital. contains instructions for the use of Validol with glucose).
1 tablet contains:
- active substances: levomenthol solution in mentilizovalerate (validol) - 60 mg; dextrose (glucose) monohydrate - 171 or 188 mg (depending on the manufacturer);
- auxiliary components: sucrose (sugar); additionally, depending on the manufacturer - calcium stearate, low molecular weight medical polyvinylpyrrolidone (povidone), potato starch, stearic acid, aerosil (colloidal silicon dioxide).
Pharmacological properties
Pharmacodynamics
Validol has a calming effect on the central nervous system, showing a sedative effect. Shows a moderate reflex vasodilator effect associated with irritation of the sensitive endings of nerve fibers. It activates the production and release of endorphins, enkephalins, and other neuropeptides, including kinins (as a result of irritation of the receptor cells of the mucous membrane), which are actively involved in the regulation of vascular wall permeability and the mechanisms of pain formation. After sublingual administration of the active substance, the therapeutic effect occurs after about 5 minutes, while up to 70% of the drug is released within 3 minutes.
Dextrose (glucose) monohydrate plays an important role in redox reactions, ensures the normal course of various metabolic processes in the body.
Pharmacokinetics
When used sublingually, validol is absorbed from the oral mucosa. It is biotransformed after absorption in the liver and excreted in the form of glucuronides in the urine.
Dextrose monohydrate is completely absorbed by the body and, as a result, is not excreted by the kidneys (the detection of a substance in the urine refers to the signs of pathology).
Indications for use
The indications for Validol with glucose are:
- angina pectoris, functional cardialgia;
- hysteria, neurosis;
- headache while taking nitrates;
- motion sickness syndrome (nausea, vomiting with sea / air sickness).
Contraindications
Contraindications to the use of Validol with glucose (may vary depending on the manufacturer):
- children under 3 years old or children and adolescents up to 18 years old;
- sucrose / isomaltose deficiency, glucose-galactose malabsorption, fructose intolerance;
- violation of carbohydrate tolerance;
- the presence of hypersensitivity to any of the ingredients of the drug.
It is recommended with caution to take Validol tablets with glucose according to indications for patients with diabetes mellitus (since it contains sugar).
Validol with glucose, instructions for use: method and dosage
Validol tablets with glucose are used sublingually, it is recommended to keep them under the tongue until they are completely dissolved.
Adults take 1 tablet 2-3 times a day.
The frequency of daily use and the duration of treatment are set taking into account the effectiveness of therapy. If the effect of Validol with glucose is insufficient, or in the case when some patients do not have the expected effect within the next 5 minutes after taking it, you should consult a doctor in order to exclude a heart attack or prescribe another treatment.
In case of intense and increasing pain, especially against the background of previously diagnosed heart diseases, such as exertional angina, myocardial infarction and others, an emergency call is required.
Side effects
Against the background of prolonged use of Validol with glucose, there may be violations in the form of lacrimation, mild nausea, and dizziness. As a rule, these phenomena go away on their own. In case of aggravation of the severity of these adverse reactions or the occurrence of other undesirable conditions, it is necessary to consult your doctor.
Overdose
Symptoms of an overdose of validol include: agitation, nausea, headache, drop in blood pressure, impaired heart function (including changes in heart rate), depression of the central nervous system.
With the development of these symptoms, it is necessary to stop taking Validol with glucose and conduct symptomatic therapy.
special instructions
Patients with diabetes mellitus should take into account that 1 tablet containing 188 mg of dextrose (glucose) monohydrate also contains (depending on the manufacturer) 450 or 544 mg of sugar (sucrose), which is equivalent to 0.054 or 0.067 Bread Units (XE), respectively.
Influence on the ability to drive vehicles and complex mechanisms
With prolonged use of Validol with glucose, due to the aggravation of the risk of manifestations of undesirable reactions, the ability to perform types of work requiring the speed of psychomotor reactions and increased concentration of attention (including driving a car or other complex mechanisms) may decrease.
Application during pregnancy and lactation
During pregnancy and breastfeeding, Validol with glucose can be used only if the intended effect of therapy for the mother significantly outweighs the risk of negative effects of the drug on the fetus or child.
Pediatric use
Reception of Validol with glucose is contraindicated in persons under 3 or 18 years of age (depending on the manufacturer) due to the lack of data confirming the safety and efficacy of treatment in patients of these age groups.
Drug interactions
- nitrates: the severity of the headache that occurs during their use decreases;
- neurotropic drugs, depressing type of action: the depressing effect of these drugs on the central nervous system is aggravated.
Analogs
Validol analogues with glucose are Validol, Validol Avexima, Cormentol, Hawthorn tincture, Corvalment, Corvaltab, etc.
Terms and conditions of storage
Store out of the reach of children, protected from moisture; storage temperature * 12-18 ° C, or up to 15 ° C, or up to 25 ° C.
Expiration date * - 2 or 3 years.
Note
* storage temperature and shelf life depend on the manufacturer.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Validol with glucose
Numerous reviews of Validol with glucose that are found on medical sites are overwhelmingly positive. Almost all patients consider the drug an inexpensive, affordable, time-tested drug that has a quick effect on manifestations of neuroses, hysteria, and mood swings. Users point out that the drug is successfully used not only in the treatment of cardialgia, angioedema attacks of angioedema, but also as an antiemetic for sea and air sickness. Many people like the pleasant and refreshing taste of Validol with glucose.
The disadvantages of the remedy include the existing contraindications to its intake and the presence of sugar in the composition. There are no complaints about adverse events.
Price for Validol with glucose in pharmacies
The price of Validol with glucose, sublingual tablets, can be: 6-15 rubles. for 10 pcs. in a package, 40-50 rubles. for 20 pcs. packaged.
Validol with glucose: prices in online pharmacies
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Drug name Price Pharmacy |
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Validol glucose tablets sublingual 10 pcs. RUB 11 Buy |
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Validol with glucose 60mg tablets 10 pcs. RUB 25 Buy |
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Validol glucose tablets sublingual 10 pcs. RUB 25 Buy |
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Validol with glucose 60 mg tablets sublingual 10 pcs. RUB 39 Buy |
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Validol with glucose 60 mg tablets sublingual 20 pcs. RUB 45 Buy |
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Validol glucose tablets sublingual 20 pcs. RUB 47 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
