Glycine
Glycine: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Glycine
ATX code: N07XX
Active ingredient: glycine (glycine)
Manufacturer: LLC "Medical Research and Production Complex" BIOTIKI "(Russia)
Description and photo update: 2019-16-08
Prices in pharmacies: from 25 rubles.
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Glycine is a drug that helps to improve the metabolism of the brain.
Release form and composition
The drug is produced in the form of sublingual tablets: flat-cylindrical, white with elements of marbling, with a chamfer (50 pieces in blisters, 1 package in a cardboard box).
The composition of 1 tablet includes:
- Active ingredient: microencapsulated glycine - 100 mg;
- Auxiliary components: magnesium stearate - 1 mg; water-soluble methylcellulose - 1 mg.
Pharmacological properties
Glycine regulates metabolism, normalizes and starts the processes of protective inhibition in the central nervous system, increases mental performance, reduces psycho-emotional stress. It is characterized by antitoxic, antioxidant, glycine and GABAergic, α 1 -adrenoceptor blocking effects. The drug is a regulator of the activity of glutamate (NMDA) receptors, which provides a decrease in conflict, aggressiveness, improved social adaptation, a decrease in the toxic effect of alcohol and other drugs that depress the functions of the central nervous system, and an improvement in mood. Also, glycine reduces the severity of brain disorders in traumatic brain injury and ischemic stroke, eliminates vegetative-vascular disorders (including during menopause), facilitates falling asleep and normalizes sleep.
Pharmacodynamics
Accurate information on the pharmacodynamics of Glycine is not provided.
Pharmacokinetics
The drug easily penetrates into most tissues and biological fluids of the body, including the brain. The substance is metabolized to form carbon dioxide and water and is not accumulated in the body.
Indications for use
- Decreased mental performance;
- Deviant forms of behavior of children and adolescents;
- Psychoemotional stress, stressful situations (conflict situation, exam period);
- Ischemic stroke;
- Various organic and functional diseases of the nervous system, accompanied by emotional instability, increased excitability, sleep disturbance and decreased mental performance: neuroses, vegetative vascular dystonia (VVD) and neurosis-like conditions, the consequences of craniocerebral trauma and neuroinfections, perinatal and other forms of encephalopathy (incl. including alcoholic genesis).
Contraindications
According to the instructions, Glycine is contraindicated for use in the presence of hypersensitivity to the components of the drug.
Instructions for the use of Glycine: method and dosage
Glycine tablets should be used buccal or sublingual 100 mg (whole or in powder form after grinding).
Practically healthy adults and children with reduced mental performance, memory and attention, psychoemotional stress, mental retardation, deviant forms of behavior Glycine is prescribed 2-3 times a day, 1 tablet. Duration of admission is 2-4 weeks.
Children under 3 years old with lesions of the nervous system (organic and functional), which are accompanied by increased excitability, sleep disturbances and emotional lability are prescribed 2-3 times a day, 1/2 tablet (50 mg) for 1-2 weeks. In the future, for 7-10 days, Glycine is taken 1 time per day. The daily dose is 100-150 mg, the course dose is from 2000 to 2600 mg. Adults and children over 3 years old are prescribed 100 mg 2-3 times a day. The average duration of a treatment course is 1-2 weeks. If necessary, therapy can be carried out within 1 month. According to the indications, it is possible to carry out a second course with an interval of 30 days.
In case of sleep disturbance, the drug should be taken immediately before bedtime or 20 minutes before bedtime. Depending on age, the dose can vary between 50-100 mg.
In ischemic cerebral stroke, Glycine is administered sublingually or buccally with one teaspoon of water at a dose of 1000 mg during the first 3-6 hours after the onset of the stroke. Within 1-5 days, the drug should be taken in the same dose. Over the next 30 days, tablets are taken 3 times a day, 1-2 pcs.
In narcology, the drug is used as a means of increasing mental performance, as well as to reduce psycho-emotional stress during remission in case of organic lesions of the central and peripheral nervous system and the phenomena of encephalopathy. Glycine is usually prescribed for 14-30 days 2-3 times a day, 1 tablet. If necessary, it is possible to repeat courses (4-6 times a year).
Side effects
During therapy, allergic reactions may develop.
Overdose
An overdose in humans is considered impossible because it is one of the amino acids found in the human body. With increasing dosage, the effectiveness of the drug increases. The structural formula of glycine ensures its participation in the metabolism in brain cells.
special instructions
Before using Glycine, as well as in cases of the development of uncharacteristic symptoms, you should consult your doctor.
Application during pregnancy and lactation
The use of the drug for disorders of the functioning of the nervous system during pregnancy and lactation is permissible, however, only after consultation with a specialist who will determine the woman's health status and individually select a therapeutic dose.
Clinical studies of the safety of Glycine for pregnant women have not been conducted, therefore, in this category of patients, it is prescribed with caution, taking into account contraindications and side effects.
It is allowed to take Glycine tablets during lactation due to its mild effect on the body. The concentration of the substance in breast milk is insignificant, but you should consult your doctor before starting treatment.
Drug interactions
Glycine can reduce the severity of the side effects of anxiolytics, antipsychotics (antipsychotics), antidepressants, anticonvulsants and hypnotics.
Analogs
Glycine analogues are: Glycine Forte, Glycine-Bio Pharmaplant, Glycine-Canon, Glycine-MHFP, Glycised, Tenoten, Memsidol, Parkon, Phenibut, Enerion.
Terms and conditions of storage
Store in a dark, dry place out of reach of children at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Glycine
Now there are numerous reviews about Glycine, which is often prescribed to older children and even newborns. Many patients claim that they often undergo treatment with the drug, as it helps to normalize sleep and reduce the severity of stress. Also, it has practically no contraindications and has an affordable price.
Parents claim that the use of Glycine in children gives very good results soon after the start of the course of therapy. However, there are reports of drug ineffectiveness. Doctors speak positively about the drug, claiming that it is absolutely harmless and can be used even in infants to combat hypertonicity and anxiety. Adverse reactions of the drug are occasionally mentioned, including individual intolerance and allergic reactions. Glycine should be used only after consulting a specialist and in accordance with the developed treatment regimen.
Price for Glycine in pharmacies
On average, the price of Glycine in pharmacy chains is 25-40 rubles (the package includes 50 tablets).
Glycine: prices in online pharmacies
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Drug name Price Pharmacy |
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Glycine 100 mg sublingual tablets 50 pcs. RUB 25 Buy |
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Glycine tablets 110 mg tablets 50 pcs. RUB 25 Buy |
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Glycine tablets sublingual. 100mg 50 pcs. 34 rbl. Buy |
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Glycine tablets buccal and sublingual 100mg 50pcs RUB 37 Buy |
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Zdravsiti Glycine 110 mg sublingual tablets 50 pcs. RUB 37 Buy |
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Glycine Extra 600 mg tablets 20 pcs. RUB 42 Buy |
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Glycine forte 250 mg buccal tablets 30 pcs. 43 rbl. Buy |
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Glycine Forte buccal tablets 250mg 30 pcs. RUB 45 Buy |
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Glycine 100 mg sublingual tablets 100 pcs. RUB 48 Buy |
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ZdravCity Glycine tablets 110 mg 50 pcs. RUB 50 Buy |
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Glycine Extra sublingual tablets 20 pcs. RUB 63 Buy |
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Glycine Forte Evalar 300 mg tablets 20 pcs. RUB 63 Buy |
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Evalar Glycine Forte tablets 20 pcs. RUB 68 Buy |
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Glycine tablets sublingual. 100mg 100 pcs. RUB 68 Buy |
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Glycine Forte Vitamir 300 mg cherry-flavored tablets 30 pcs. 74 RUB Buy |
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Glycine Ka lozenges 18 pcs. 92 RUB Buy |
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Evalar Glycine Forte tablets 60 pcs. 142 RUB Buy |
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Glycine Forte Evalar 300 mg lozenges 60 pcs. 142 RUB Buy |
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Zdravsiti glycine with group vitamins in a tablet for rassas. 800 mg 60 pcs. RUB 165 Buy |
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Zdravsiti glycine with B vitamins lozenges 60 pcs. RUB 165 Buy |
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Doppelgerz active Glycine + B-Vitamins 610 mg capsules 30 pcs. 197 RUB Buy |
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Glycine Forte Evalar 500 mg lozenges 60 pcs. 199 RUB Buy |
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Glycine D3 400 IU + 600 mg tablets instant with Exotic flavor 12 pcs. RUB 300 Buy |
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Reviews Glycine D3 RUB 300 Buy |
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Glycine D3 tablets 600 mg + 400 IU 12 pcs. 497 r Buy |
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NOW Glycine Glycine 1000 mg capsule 100 pcs 1350 RUB Buy |
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Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
