Methylethylpyridinol
Methylethylpyridinol: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Methylethylpiridinol
ATX code: C05CX, S01XA
Active ingredient: methylethylpyridinol (Methylethylpiridinol)
Producer: ATOLL (Russia), ELLARA (Russia), DEKO Company (Russia)
Description and photo update: 2019-08-07
Prices in pharmacies: from 154 rubles.
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Methylethylpyridinol is an antioxidant agent.
Release form and composition
Dosage form - solution for injection: transparent, colorless or slightly yellowish liquid [1 ml in ampoules made of neutral colorless glass or glass with a class of resistance to hydrolysis HGA1, in a cardboard box 5 or 10 ampoules complete with an ampoule scarifier (when packing ampoules with a ring or a break point, the scarifier is not inserted) or 1–2 cell contour packs of 5 ampoules and instructions for the use of Methylethylpyridinol; packing for hospitals - in a cardboard box 4, 5, 10, 50 or 100 cell contour packs of 5 ampoules].
Composition of 1 ml solution:
- active substance: methylethylpyridinol (in the form of hydrochloride) - 10 mg;
- auxiliary components: 0.1 M hydrochloric acid solution, water for injection.
Pharmacological properties
Pharmacodynamics
Methylethylpyridinol - antioxidant, inhibitor of free radical processes.
It has a beneficial effect on the blood coagulation system: it reduces blood viscosity, lengthens its coagulation time, inhibits platelet aggregation. It stabilizes the membranes of erythrocytes and blood vessel cells, increases the resistance of erythrocytes to hemolysis and mechanical injury.
Increases the content of cyclic nucleotides in platelets (cyclic adenosine monophosphate and cyclic guanosine monophosphate), reduces the permeability of the vascular wall, promotes resorption of hemorrhages, and has fibrinolytic activity.
Improves microcirculation in eye tissues, including retinal vessels. It has a retinoprotective effect, protects the retina from the damaging effects of high intensity light.
Pharmacokinetics
The volume of distribution of methylethylpyridinol is 5.2 liters. Total clearance - 0.2 l / min. The drug is metabolized in the liver. It is excreted from the body by the kidneys. The half-life is 18 minutes.
Indications for use
Methylethylpyridinol is used as part of complex therapy for the following diseases / conditions:
- degenerative diseases of the cornea;
- intraocular and subconjunctival hemorrhages of various origins;
- central and peripheral chorioretinal dystrophy;
- angioretinopathy (including diabetic);
- angiosclerotic macular degeneration (dry form);
- thrombosis of the central retinal vein and its branches;
- complications of myopia;
- 2nd degree burns and corneal injuries;
- detachment of the choroid in the postoperative period after surgery for glaucoma;
- eye damage with high intensity light (laser radiation during laser coagulation) - treatment and prevention.
Contraindications
Absolute:
- age up to 18 years;
- hypersensitivity to any component of the drug.
With caution and only after assessing the benefits and risks, methyl ethylpyridinol is prescribed to pregnant and breastfeeding women.
Methylethylpyridinol, instructions for use: method and dosage
Solution for injection Methylethylpyridinol is administered parabulbarno (p / b) or subconjunctivally (s / c). The drug is used as part of complex therapy.
Recommended dosage regimens:
- dystrophic diseases of the cornea: s / c, 0.5 ml 1 time per day for a course of 10-30 days;
- intraocular and subconjunctival hemorrhages of various origins: s / c or s / b, 0.5 ml once a day for 10-15 days;
- central and peripheral chorioretinal dystrophy, dry form of angiosclerotic macular degeneration: p / b, 0.5 ml once a day for 10-15 days;
- thrombosis of the central retinal vein and its branches: p / b, 0.5 ml 1 time per day for a course of 10-15 days;
- complicated myopia: p / b, 0.5 ml once a day for 10-30 days, if necessary, 2-3 times a year, the courses are repeated;
- corneal injuries and burns of the 2nd degree: p / w, 0.5 ml once a day for 10-15 days;
- detachment of the choroid in the postoperative period after surgical treatment of glaucoma: s / c or s / b, 0.5–1 ml every other day, the course of treatment consists of 10 injections;
- protection of the retina during laser coagulation (including with limiting and destructive coagulation of tumors): p / w, 0.5-1 ml for 24 hours and 1 hour before coagulation, then - 0.5 ml once a day for for 2-10 days.
Side effects
- local reactions: burning, pain, hyperemia, itching, compaction of paraorbital tissues (does not require special treatment, dissolves on its own);
- allergic reactions: itching, peeling of the skin, edema, hyperemia;
- from the nervous system: drowsiness, short-term agitation;
- on the part of the cardiovascular system: skin rashes, increased blood pressure.
Overdose
In case of an overdose of methylethylpyridinol, the following symptoms are possible: headache, drowsiness, agitation, increased blood pressure, pain in the heart, epigastric discomfort, nausea, blood clotting disorders.
Treatment is symptomatic.
special instructions
During the period of drug therapy, it is necessary to monitor blood pressure and indicators of the blood coagulation system.
Influence on the ability to drive vehicles and complex mechanisms
Patients with central nervous system side effects, such as drowsiness, should refrain from driving and performing work that requires precise movements and concentration.
Application during pregnancy and lactation
For pregnant and breastfeeding women, methyl ethylpyridinol can be prescribed only if the expected benefit from the forthcoming therapy outweighs the possible risks to the fetus / child.
Pediatric use
The use of Methylethylpyridinol is contraindicated in children and adolescents under the age of 18.
With impaired renal function
Information not provided by the manufacturer.
For violations of liver function
Information not provided by the manufacturer.
Use in the elderly
Information not provided by the manufacturer.
Drug interactions
Methylethylpyridinol is pharmaceutically incompatible with other drugs, therefore it is forbidden to mix it in the same syringe with other drugs.
Analogs
Analogues of Methylethylpyridinol are: Vixipin, Cardioxipin, Methylethylpyridinol-Eskom, Emoxy-optic, Emoxibel, Emoxipin, Emoxipin-AKOS, etc.
Terms and conditions of storage
Store at temperatures below 25 ° C, protected from light, out of reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Methylethylpyridinol
Reviews of Methylethylpyridinol are few, but positive. The drug has demonstrated high efficiency and is inexpensive. However, according to patients, it is much more convenient to use medicines with the same active ingredient in the form of eye drops.
Methylethylpyridinol is often used both for various ophthalmic diseases and for circulatory disorders and cardiovascular pathologies.
Price for Methylethylpyridinol in pharmacies
The approximate price for Methylethylpyridinol, depending on the region of sale and the pharmacy chain, can range from 43 to 68 rubles. for a pack of 10 ampoules of 1 ml of solution for injection 10 mg / ml.
Methylethylpyridinol: prices in online pharmacies
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Drug name Price Pharmacy |
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Methylethylpyridinol injection 10mg / ml ampoules 1ml 10 pcs 154 RUB Buy |
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Methylethylpyridinol 10 mg / ml solution for injection 1 ml 10 pcs. 154 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
