Anaferon
Anaferon: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Anaferon
ATX code: J05AX, L03
Active ingredient: antibodies to human gamma-interferon affinity purified (affinity purified antibodies to human gamma-interferon)
Manufacturer: NPF Materia Medica Holding LLC (Russia)
Description and photo update: 2019-26-08
Prices in pharmacies: from 166 rubles.
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Anaferon is an antiviral immunomodulatory agent that increases the amount of antibodies, activates the cellular and humoral components of immunity and the formation of interferon.
Release form and composition
Anaferon for adults and Anaferon for children are produced, both drugs are produced in the form of tablets for sublingual use (20 pcs. In blisters, 1 package in a cardboard box).
The preparation contains 3 mg affinity purified antibodies to human interferon gamma.
Pharmacological properties
Pharmacodynamics
When using Anaferon as a prophylactic and therapeutic agent, it exhibits antiviral and immunomodulatory effects. In the course of various experiments and clinical studies, it was found that the drug is effective against respiratory syncytial virus (RS virus), influenza and parainfluenza viruses, adenovirus, herpes simplex viruses of types 1 and 2 (genital herpes, labial herpes), and other herpes viruses (infectious mononucleosis, chickenpox), calicivirus, enterovirus, coronavirus, rotavirus, tick-borne encephalitis virus. The drug reduces the content of the virus in the affected tissues, activates the formation of interferon gamma (IFNγ) and endogenous early interferons (IFNα / β).
The drug is a stimulator of the cellular and humoral immune response, induces the synthesis of antibodies [including secretory immunoglobulin A (IgA)], enhances the functions of T-helpers (Tx) and T-effectors, normalizes their ratio. Anaferon also increases the functional reserve of Tx and other cells responsible for the immune response, is an inducer of a mixed Tx1 and Tx2-type immune response, increases the production of Th1 (IL-2, IFNγ) and Tx2 (IL-4, 10) cytokines, modulates (leads to standard values) the balance of Tx1 / Tx2 activities. The drug increases the functional activity of natural killer cells (NK cells) and phagocytes. It is characterized by antimutagenic properties.
Pharmacokinetics
Modern physicochemical types of analysis (gas chromatography-mass spectrometry, high-performance liquid chromatography, gas-liquid chromatography) have a sensitivity that does not allow an accurate assessment of the concentration of Anaferon's active components in organs, tissues and biological fluids. In this regard, the study of the pharmacokinetic parameters of the drug is not possible.
Indications for use
For both children and adults, Anaferon is indicated in the following cases:
- Complex therapy of mixed and bacterial infections;
- Treatment of ARVI, influenza, chronic and acute cytomegalovirus and herpes infections;
- Treatment and prevention of immunodeficiency states and infections, complications of acute respiratory viral infections, influenza.
Contraindications
According to the instructions, Anaferon is contraindicated in case of intolerance to its components.
During pregnancy and lactation, the drug is prescribed with caution.
Instructions for the use of Anaferon: method and dosage
Anaferon tablets for adults are prescribed 1 pc. from 3 to 6 times a day, with signs of improvement, you can take the drug 1 time a day for 8-10 days.
Anaferon for children is prescribed starting from the age of the child.
In case of respiratory diseases, when the first symptoms appear, the drug is used according to the following scheme: in the first 2 hours, every 30 minutes, take a tablet and another 3 tablets during the first day. Then you should take 1 tablet 3 times a day until complete recovery.
For the prevention of bacterial complications, Anaferon tablets are prescribed, 1 pc. 1 time per day on an empty stomach for 8-12 days.
When taking the drug, the tablet is not swallowed until it is completely dissolved, and for children from a month to 3 years old, the drug is dissolved in a tablespoon of boiled water.
Side effects
Side effects are rare. In some cases, the drug can cause hypersensitivity to the components that make up its composition.
Overdose
At the moment, there are no reports of cases of overdose. In case of accidental intake of the drug in high doses, dyspeptic phenomena associated with the fillers that make up its composition can be observed.
special instructions
Since the product contains lactose, the use of the drug is not recommended for patients with glucose malabsorption syndrome, with congenital galactosemia or lactase deficiency.
Application during pregnancy and lactation
The safety of prescribing Anaferon to pregnant and lactating women has not yet been proven. If necessary, drug treatment should carefully weigh the possible risks to the fetus or child and the potential benefits of the course of treatment for the mother.
Pediatric use
Children over 1 month old and adolescents under 18 years of age are shown the use of Anaferon for children according to indications in compliance with the dosage regimen prescribed by the doctor.
Analogs
Analogues of Anaferon are: Immunal, Echinacea compositum, Tsitovir-3, Cycloferon, Galavit, Amiksin, Polyoxidonium, Derinat, Erbisol, etc.
Terms and conditions of storage
Anaferon should be stored in a dry and dark place, out of the reach of children, at a temperature not exceeding 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Anaferon
They are met as positive reviews about Anaferon, in which patients report the safety and effectiveness of this homeopathic remedy, which has a pronounced antiviral and immunostimulating effect. So also negative responses, mainly from parents whose children the drug did not bring the promised relief of the condition.
At the same time, many are sure that, subject to the treatment regimen, the drug can reduce the incidence of ARVI and other infectious diseases. Some doctors also consider it to be a quality immunomodulator.
The price of Anaferon in pharmacies
On average, the price of Anaferon (lozenges) is for 20 pcs. in the package varies from 207 to 265 rubles.
Anaferon: prices in online pharmacies
Drug name Price Pharmacy |
Anaferon lozenges 20 pcs. 166 r Buy |
Anaferon children's lozenges 20 pcs. 195 RUB Buy |
Anaferon children's tablets for rassas. 20 pcs. 243 r Buy |
Anaferon tablets for rassas. 20 pcs. 248 r Buy |
Anaferon oral drops for children 25 ml 1 pc. 254 r Buy |
Reviews Anaferon for children 254 r Buy |
Anaferon baby drops for internal approx. fl. with drip. 25ml 271 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!