Amizon

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Amizon: instructions for use and reviews

1. Release form and composition
2. Pharmacological properties
3. Indications for use
4. Contraindications
5. Method of application and dosage
6. Side effects
7. Overdose
8. Special instructions
9. Application during pregnancy and lactation
10. Drug interactions
11. Analogs
12. Terms and conditions of storage
13. Terms of dispensing from pharmacies
14. Reviews
15. Price in pharmacies

Latin name: Amizon

ATX code: J05AX

Active ingredient: Enisamia iodide (Enisamium iodide)

Manufacturer: Farmak PAO (Ukraine)

Description and photo update: 2019-16-09

Prices in pharmacies: from 540 rubles.

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Amizon is an antiviral, antipyretic and anti-inflammatory drug that suppresses influenza A viruses.

Release form and composition

The drug is available in the form of tablets (250 mg each) in blisters of 10 or 20 pieces. One carton contains 1 pack.

In addition, Amizon for children is produced in the form of tablets of 0.125 g, which are prescribed to children aged 6 to 12 years. There is also a preparation for children in the form of a syrup (Amizonchik), which is intended for children from 3 years old for the treatment of ARVI and influenza.

The active ingredient in the composition of the drug is methylbenzylcarbamidopyridinium iodide.

Pharmacological properties

Pharmacodynamics

Amizon is an antiviral drug belonging to the group of isonicotinic acid derivatives. It effectively inhibits the activity of influenza viruses and other pathogens of acute respiratory infections due to a direct (inhibitory) effect on the process of viral penetration through cell membranes.

Methylbenzylcarbamidopyridinium (enisamium) iodide - the active component of Amizon - exhibits interferonogenic properties and leads to an increase in the content of endogenous interferon (α-interferon and γ-interferon) in blood plasma by about 3-4 times. Amizon improves the body's resistance to viral infections, eliminates acute clinical symptoms of viral intoxication, and provides a reduction in the duration of the disease.

Pharmacokinetics

After oral administration, enisamium iodide quickly enters the bloodstream, and its maximum concentration in the blood is detected after 2-2.5 hours. The half-life is 13-14 hours. The active component of Amizon is metabolized in the liver, but it is excreted from the tissues rather quickly (the half-life is 2-3 hours). Enisamium iodide is excreted from the body through the kidneys in the form of metabolites in the amount of 90–95% of the dose taken.

Indications for use

According to the instructions, Amizon is used for:

Respiratory viral infections;
Flu;
Chickenpox;
Rubella;
Corey;
Parotitis;
Chemoprophylaxis of hepatitis A and E;
Cat scratch disease (fellinosis).

Also, the drug is effective as part of complex therapy for diseases and conditions such as:

Bacterial, viral-bacterial, viral pneumonia and tonsillitis;
Meningitis and meningoencephalitis of viral etiology;
Skin-articular form of erysipeloid;
Hepatitis A and E;
Herpetic infection;
Pain syndromes with osteochondrosis, arthritis, herniated intervertebral discs.

Contraindications

In case of hypersensitivity to the components of the drug, including iodine;
In the first trimester of pregnancy;
With severe forms of liver and kidney damage;
Children under 6 years of age.

Instructions for the use of Amizon: method and dosage

The drug should be taken orally after meals, without crushing or chewing. The maximum single dose should not exceed 1 g, and the daily dose should not exceed 2 g.

Usually, the course of treatment for adults, if there are no other recommendations, lasts 5-7 days according to the following scheme: 1-2 tablets (1 tablet corresponds to 0.25 g) 2 to 4 times a day.

For children aged 6 to 12 years, the same duration of treatment is provided as for adults, with a reduced dosage: 1/2 tablet 2-3 times a day.

Positive reviews about Amizon confirm its effectiveness for the prevention of influenza and ARVI. For prophylaxis, adults should take 1 tablet daily for 3-5 days, then 1 tablet every 2-3 days for 2-3 weeks. For children 6-12 years old, the prophylactic dose is 1/2 tablet 1 time in 2 days for 3 weeks. Children 12-16 years old should take 1 tablet every other day for 14-21 days.

The instructions for the drug indicate the following schemes of use, each of which provides for three doses of the drug per day:

With meningoencephalitis - 1 tablet for 10 days;
With the complex therapy of pneumonia - 1 tablet for 10-15 days;
With the complex therapy of viral hepatitis - 1 tablet during the first 5 days of illness;
For pain syndromes - 1-2 tablets for 1-2 weeks.

The scheme for using Amizonchik syrup for children is as follows:

Children 3-4 years old - 5 ml;
Children 4-5 years old - 6 ml;
Children 5-6 years old - 7 ml;
Children 6-12 years old - 12 ml each (if they cannot swallow Amizon for children in the form of tablets).

The syrup should be taken 3 times a day, preferably after meals, with a small amount of water.

After oral administration, the drug quickly enters the bloodstream, where its maximum concentration is observed after 2-2.5 hours. The drug is metabolized in the liver, excreted from the body in the form of metabolites (95%) in the urine.

Side effects

Amizon is well tolerated, however, clinical studies indicate that in rare cases, slight edema of the oral mucosa and bitterness in the mouth may occur.

The undesirable consequences of using the drug disappear immediately after its withdrawal and do not require additional treatment.

Overdose

In case of an overdose, there is often an increase in the manifestations of side effects of the drug. In this case, gastric lavage and symptomatic therapy are recommended.

special instructions

The analgesic activity of Amizon corresponds to that of amidopyrine and analgin, despite the fact that this drug begins to act later, anesthesia with its use lasts longer.

The agent, unlike many analgesics, is low-toxic, does not have a negative effect on bone marrow hematopoiesis and the blood picture in general, and also does not irritate the mucous membrane of the gastrointestinal tract.

The use of the drug as an antipyretic agent in its effectiveness is significantly superior to ibuprofen, butadione and salicylates.

The medicinal product does not affect the ability to drive mechanical equipment and vehicles.

Application during pregnancy and lactation

In the first trimester of pregnancy, treatment with Amizon is categorically contraindicated. At a later date, the decision on the advisability of prescribing this drug can only be made by a doctor. There is no information on the effect of enisamium iodide on the health of a child when using the drug during breastfeeding.

Drug interactions

There is no reliable information on the interaction of enisamium iodide with other drugs. The drug potentiates the action of immunomodulating and antibacterial agents. The combination of Amizon with ascorbic acid and other vitamins is considered appropriate. It is also permissible to administer it simultaneously with recombinant interferon.

Analogs

The following drugs are analogs of Amizon:

Enisamium iodide;
Altabor;
Flavoside;
Mangogherpine;
Engystol.

Terms and conditions of storage

Store Amizon in a dark place at a temperature not exceeding 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Amizon

Numerous reviews about Amizon are quite contradictory. Many patients consider it a very effective antiviral drug, but some users note the uselessness of the pills and the lack of their positive effect on the body and the state of the immune system after the course of treatment. At the same time, most doctors claim that enisamium iodide has both therapeutic and prophylactic effects.

According to some reviews, the drug helps prevent infection with influenza and SARS during an epidemic. In this case, there are references to the side effects of the drug, for example, the appearance of bitterness in the mouth.

The price of Amizon in pharmacies

The approximate price for Amizon is 340–400 rubles (for a pack of 20 tablets).

Amizon: prices in online pharmacies

Drug name

Price

Pharmacy

Amizon 250 mg film-coated tablets 30 pcs.

RUB 540

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Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!