Ferlatum Foul
Ferlatum Foul: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. For violations of liver function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Ferlatum Fol
ATX code: B03AB09
Active ingredient: iron protein succinylate (iron protein succinylate); calcium folinate
Manufacturer: Italy, Italfarmako S.p. A.
Description and photo update: 2018-22-10
Prices in pharmacies: from 547 rubles.
Buy
Ferlatum Foul - antianemic drug; an iron preparation that stimulates hematopoiesis.
Release form and composition
Ferlatum Fol dosage form - oral solution: two-component preparation, contains a bottle with a solution and a sealed dispenser cap (container cap) with powder; solution - a transparent brownish liquid with a characteristic pleasant cherry aroma; powder - odorless, whitish with a yellowish tinge (15 ml of solution in polyethylene bottles, complete with container caps of 100 mg of powder; in a cardboard box 10 or 20 sets).
Oral solution (15 ml bottle) contains:
- active substance: trivalent iron (Fe 3+) - 40 mg (in the form of iron succinylate protein - 800 mg);
- auxiliary components: propylene glycol, sorbitol, sodium propyl parahydroxybenzoate, sodium methyl parahydroxybenzoate, sodium saccharinate, cherry flavor (wild black cherry flavor concentrated, amyl acetate, other ethers in small amounts, vanillin, oil of clove buds, diethylene glycol ether, diethylene glycol ether), purified water.
Powder for solution preparation (100 mg container cap) contains:
- active substance: calcium folinate - 0.2 mg (in the form of calcium folinate pentahydrate - 0.235 mg), which corresponds to a folinic acid content of 0.185 mg;
- auxiliary components: mannitol.
Pharmacological properties
Pharmacodynamics
Ferlatum Fol - a drug used to treat anemia, containing iron and calcium folinate; compensates for the deficiency of iron and folate in the body.
The main function of iron is to transport oxygen to tissues and organs. Being a part of hemoglobin, iron-containing enzymes-cytochromes, myoglobin, iron carries out the transfer of electrons and acts as a catalyst for hydroxylation, oxidation, and other metabolic reactions.
Ferlatum Fol contains iron in the form of a succinylate protein, which is a complex compound in which ferric atoms are enclosed in a semi-synthetic protein carrier, which prevents ulceration of the gastric mucosa. Dissolving in the duodenum, the protein carrier releases the trace element in the zone of optimal absorption.
Fe 3+ enters the bloodstream from the intestine by active absorption, as a result of which its overdose and intoxication are practically impossible.
Calcium folinate - the second active component of the drug - is a calcium salt of folinic acid, which compensates for the lack of folate in the body.
Indications for use
- latent and clinically pronounced iron deficiency (iron deficiency anemia) and folate deficiency (therapy);
- iron and folate deficiency in pregnant women, nursing mothers, during the period of active growth, as a result of prolonged bleeding, with inadequate and unbalanced nutrition (prevention).
Contraindications
Absolute:
- disruption of iron utilization processes [including lead and (or) sideroachrestic anemia];
- hemochromatosis;
- non-megaloblastic anemia (including hemolytic, megaloblastic anemia and anemia caused by vitamin B 12 deficiency);
- cirrhosis of the liver;
- chronic pancreatitis;
- hypersensitivity to any component of the drug.
Relative contraindications (conditions in which the drug is used with caution): gastric ulcer and duodenal ulcer, malabsorption due to pathology of the small intestine (including malabsorption syndrome, enteritis, resection of the small intestine, gastric resection according to Billroth II with the inclusion of the duodenum).
Instructions for the use of Ferlatum Foul: method and dosage
The prepared Ferlatum Fol solution is intended for oral administration. Take the drug before meals or immediately after meals.
The recommended dosage regimen for different categories of patients, if there are no other doctor's prescriptions:
- adults: 1–2 bottles (equivalent to Fe 3+ - 40–80 mg; calcium folinate pentahydrate - 0.235–0.470 mg) per day, divided into 2 doses;
- children from the neonatal period: 1.5 ml / kg (equivalent to Fe 3+ - 4 mg / kg; calcium folinate pentahydrate - 0.0235 mg / kg) per day, divided into 2 doses;
- pregnant women: for the prevention of iron deficiency anemia - 1 bottle per day; for the treatment of latent or clinically pronounced iron deficiency - 1-2 vials per day, divided into 2 doses.
After reaching normal levels of iron and hemoglobin in the blood serum, it is recommended to continue therapy at a maintenance dose for at least 8-12 weeks.
The sequence of actions when preparing a solution for oral administration:
- forcefully press the perforator of the container cap so that the powder in it spills out into the solution in the bottle;
- shake the resulting contents of the bottle vigorously;
- remove the dispenser cover;
- drink the solution.
Side effects
As a result of treatment with Ferlatum Foul, in rare cases, gastrointestinal disorders may occur, which occur when the dose of the drug is reduced or when therapy is canceled.
Overdose
Until now, signs of intoxication with Ferlatum Fol and its excessive intake into the body have not been observed.
special instructions
It is recommended to use the drug continuously for no more than six months; exceptions may be cases of chronic blood loss (including hemorrhoids and menorrhagia), as well as pregnancy.
Due to the potential risk of developing hypersensitivity reactions, patients with milk protein intolerance should be prescribed the drug with caution.
Due to the fact that sorbitol is a part of Ferlatum Fol, it is impossible to use the drug in patients with hereditary fructose intolerance.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Ferlatum Foul does not affect the performance of potentially hazardous types of work that require increased concentration of attention and increased speed of psychomotor reactions (in particular, driving a vehicle).
Application during pregnancy and lactation
For the prevention and treatment of iron and folate deficiency that develops during pregnancy and during breastfeeding, the use of Ferlatum Fol is especially recommended.
Pediatric use
Ferlatum Foul is used in pediatric practice from the neonatal period according to indications.
For violations of liver function
Patients with liver cirrhosis are contraindicated to take the drug.
Drug interactions
- ascorbic acid in a dose of more than 200 mg: may increase the absorption of iron;
- antacids: may reduce iron absorption;
- chloramphenicol: causes a delayed response to iron therapy;
- antagonists of histamine H 2 -receptors: pharmacological interaction with Ferlatum Foul is absent;
- some antineoplastic and anti-leukemic drugs (including aminopterin, methotrexate and other pterin derivatives): exhibit folate antagonist properties.
With simultaneous use with other drugs / drugs, their interaction with Ferlatum Foul was not observed.
Analogs
Ferlatum Foul analogs are Aktiferrin, Sorbifer Durules, Maltofer, Totema.
Terms and conditions of storage
Store in a dry place at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews of Ferlatum Foul
Since the drug is recommended to be taken, including during pregnancy, there are a lot of reviews about Ferlatum Foul, as well as discussions of its effectiveness in various forums. Most of those who have taken the drug agree that it is effective, convenient to use and effective, since it really increases the level of hemoglobin, and after the completion of the course of treatment, this indicator remains stable.
Patients debate about taste, which is not surprising, given the changes in taste sensations in pregnant women. Some say that the solution has a pleasant cherry taste, others call it cloying and nauseous.
Adverse reactions are extremely rare. Almost unanimously, the high cost of the drug is called a disadvantage.
Price for Ferlatum Foul in pharmacies
The estimated price of Ferlatum Foul for a package of 10 vials with a solution, sealed with a dispenser cap with a powder, is about 615 rubles.
Ferlatum Fall: prices in online pharmacies
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Drug name Price Pharmacy |
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Ferlatum Fol oral solution 15 ml 10 pcs. 547 r Buy |
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Ferlatum Foul solution for internal approx. 15ml 10 pcs. 587 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
