Exoderil
Instructions for use:
- 1. Indications for use
- 2. Contraindications for use
- 3. Method of application, dosage
- 4. Side effects
- 5. Application during pregnancy
- 6. Interaction with other drugs
- 7. Overdose
- 8. Reviews
- 9. Analogs
Prices in online pharmacies:
from 353 rub.
Buy
Exoderil is a topical antifungal drug. The active ingredient is naftifine, a synthetic antimycotic substance of the allylamine group. Exoderil has a fungicidal, fungistatic, bactericidal effect. The mechanism of action is to inhibit the biosynthesis of ergosterol in the fungal cell by acting on squalene epoxidase. The drug does not affect the cytochrome P450 system. Exoderil causes a lack of ergosterol and the accumulation of squalene in the fungal cell, resulting in the death of the microorganism. Exoderil is active against dermatophytes (Trichophyton, Epidermophyton, Microsporum), fungi of the genus Candida, Sporotrix schenckii, and molds. In addition, the drug acts against some gram-positive, gram-negative microorganisms, Malassezia furfur. When applied topically, Exoderil penetrates well into all layers of the skin, while creating a therapeutic concentration.
About 6% of the active substance enters the systemic circulation. The drug is partially metabolized, excreted in bile and urine. The half-life is 2-3 days.
Indications for use of Exoderil
According to the instructions for Exoderil, this drug is used for fungal skin diseases, which are caused by microorganisms sensitive to naftifine:
- epidermophytosis of skin folds, feet (caused by Epidermophyton floccosum including);
- trichophytosis (caused by Trichophyton rubrum, Trichophyton mentagrophytes);
- fungal pathology of the scalp (microsporia);
- skin lesions of candidal etiology;
- onychomycosis;
- pityriasis versicolor;
- mycoses complicated by secondary bacterial infection;
- fungal infection of the external auditory canal.
Contraindications to the use of Exoderil
According to the instructions for Exoderil, the drug is contraindicated in case of hypersensitivity to naftifine.
It is forbidden to use Exoderil on damaged skin areas (wound surfaces, burns).
Method of application, dosage
Exoderil in the form of a cream, solution is used only externally. The preparation is applied to clean, dry skin. When treating the affected skin areas with the drug, it is recommended to capture a certain amount of surrounding healthy tissues (approximately 1 cm).
In case of onychomycosis, the possible amount of affected nail tissue should be removed before applying the drug. Exoderil is used once or twice a day. The cream and solution are applied in a thin layer to the affected area and rubbed lightly. The duration of therapy depends on the form of the disease, as well as the individual characteristics of patients (in particular, on the rate of nail growth), sometimes it reaches 6 months or more. The duration of treatment is determined by the doctor.
With dermatomycosis, the average duration of therapy with Exoderil is 2-4 weeks, in severe forms - up to 8 weeks.
For skin lesions of candidal etiology, treatment lasts about 4 weeks.
After achieving clinical recovery, it is recommended to use the drug for another 2 weeks in order to prevent recurrence of the disease.
In case of mycosis of the external auditory canal, a small amount of Exoderil solution is applied to a cotton turunda, then put into the ear for 5-7 minutes twice a day. The duration of treatment is at least two weeks.
It is not recommended to use Exoderil under a bandage.
Side effect
The drug is usually quite well tolerated, as evidenced by reviews of Exoderil from patients. In isolated cases, the appearance of dryness, redness of the skin at the site of application of the drug, and a burning sensation were recorded. These phenomena disappear quickly, without the need to cancel the drug.
The use of Exoderil during pregnancy
When applied topically, Exoderil has no embryotoxic and teratogenic effects. The use of the drug during pregnancy, lactation is possible under strict indications and only as directed and under the supervision of a physician.
Interaction of Exoderil with other drugs
Due to the lack of systemic action of Exoderil and its analogues, their interaction with other drugs is unlikely.
Overdose
At this time, there is no information about an overdose of Exoderil.
Reviews
Reviews of Exoderil from patients and dermatologists indicate the high clinical effectiveness of this drug. Exoderil has proven itself in the treatment of onychomycosis, dermatomycosis, candidal skin lesions. The drug is fairly well tolerated and relatively safe.
Exoderil's analogs
Currently, such analogues of Exoderil are registered: Naftifin, Fetimin.
Before using this drug, you must carefully study the instructions for Exoderil. The drug should be used exclusively as directed by a doctor.
Exoderil: prices in online pharmacies
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Drug name Price Pharmacy |
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Exoderil 1% cream for external use 15 g 1 pc. 353 r Buy |
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Exoderil cream 1% 15g 466 r Buy |
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Exoderil 1% solution for external use 10 ml 1 pc. 508 RUB Buy |
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Exoderil solution for external use. approx. 1% 10ml 523 r Buy |
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Exoderil 1% cream for external use 30 g 1 pc. 584 r Buy |
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Exoderil cream 1% 30g 758 RUB Buy |
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Exoderil 1% solution for external use 20 ml 1 pc. 770 RUB Buy |
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Exoderil solution for external use. approx. 20ml 1045 RUB Buy |
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Exoderil 1% solution for external use 30 ml 1 pc. 1187 RUB Buy |
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Exoderil solution for external use. approx. 1% 30ml 1223 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
