Tsefekon N
Latin name: Cefecon N
ATX code: N02BA55
Active ingredient: salicylamide (Salicylamide), naproxen (Naproxen), caffeine (Caffeine)
Manufacturer: NIZHFARM AO (Russia)
Description and photo update: 28.11.2018
Prices in pharmacies: from 74 rubles.
Buy
Cefekon N is a combined non-narcotic analgesic agent.
Release form and composition
Produced in the form of rectal suppositories: torpedo-shaped, white or white with a yellowish / creamy shade; the presence of a funnel-shaped recess or an air rod is possible (5 pcs. in a blister contour packaging, in a cardboard box 2 packs and instructions for use of Cefekon N).
Composition of 1 suppository:
- active substances: salicylamide - 600 mg, naproxen - 75 mg, caffeine (anhydrous) - 50 mg;
- auxiliary components: solid fat (witepsol or supposir).
Pharmacological properties
Pharmacodynamics
Cefekon N is a combined preparation with analgesic, anti-inflammatory and antipyretic effects. Its effect is due to the properties of active substances:
- salicylamide and naproxen: non-steroidal anti-inflammatory drugs (NSAIDs), the mechanism of action of which is explained by their ability to inhibit the synthesis of prostaglandins and affect the center of thermoregulation in the hypothalamus;
- caffeine: has an analeptic, psychostimulant and antispasmodic effect on smooth muscles.
Pharmacokinetics
No information provided.
Indications for use
- analgesia of mild and moderate pain syndrome: toothache and headache, migraine, sciatica, myalgia, lumbago, neuralgia, dysmenorrhea, osteoarthritis, osteochondrosis, ankylosing spondylitis and other degenerative-dystrophic diseases of the musculoskeletal system;
- reduction of elevated body temperature in case of colds, inflammatory and infectious diseases.
Contraindications
- organic diseases of the cardiovascular system;
- arterial hypertension;
- heart failure;
- swelling;
- peptic ulcer of the stomach and duodenum in the acute phase;
- severe renal / hepatic impairment;
- pathology of the vestibular apparatus;
- angle-closure glaucoma;
- insomnia;
- increased excitability;
- blood diseases;
- hypocoagulation;
- age under 16;
- pregnancy and lactation;
- complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses with intolerance to acetylsalicylic acid or other NSAIDs (currently or in history);
- hypersensitivity to any component of Tsefekon N.
The drug is recommended to be used with caution in patients over the age of 70 years.
Cefekon N, instructions for use: method and dosage
Suppositories Cefekon N are intended only for rectal use by introducing deep into the rectum after natural bowel movement or a cleansing enema (you must first release the suppository from the packaging). The patient should remain in a horizontal position for 30–40 minutes.
Patients are prescribed 1 suppository 1 to 3 times a day.
Unless the doctor has prescribed otherwise, Tsefekon N suppositories should be used as an anesthetic drug for no more than 5 days in a row, as an antipyretic agent - no more than 3 days.
Side effects
- from the central nervous system: slowing down the speed of psychomotor reactions, drowsiness, agitation, tinnitus, dizziness;
- on the part of the cardiovascular system: increased blood pressure, tachycardia;
- from the hematopoietic system: aplastic anemia, agranulocytosis, thrombocytopenia;
- from the digestive system: impaired liver and / or kidney function;
- others: pain and itching in the rectum, allergic reactions.
Overdose
There were no reports of cases of overdose of Cefekon N.
special instructions
In case of unpleasant sensations or itching in the rectum, it is recommended to cancel the drug and consult a doctor.
Influence on the ability to drive vehicles and complex mechanisms
Special studies on the effect of Cefecon N on the reaction rate and attention have not been carried out. However, given the potential central nervous system side effects, caution is advised when engaging in potentially hazardous activities, including driving.
Application during pregnancy and lactation
It is contraindicated to use the drug for pregnant and breastfeeding women.
Pediatric use
Cefekon N is not used to treat children under 16 years of age.
With impaired renal function
Prescribing suppositories for patients with severe renal failure is contraindicated.
For violations of liver function
Prescribing suppositories for patients with severe hepatic impairment is contraindicated.
Use in the elderly
With extreme caution, Cefecon N should be used in patients aged 70 years and older.
Drug interactions
Salicylamide increases the risk of developing side effects of mineralocorticosteroids, glucocorticosteroids and estrogens. Enhances the action of fibrinolytics, indirect anticoagulants and antiplatelet agents. With the simultaneous use of myelotoxic drugs, the likelihood of inhibition of cerebral circulation (hematopoiesis) increases.
Naproxen increases the toxicity of sulfonamides, phenytoin and methotrexate. Reduces the antihypertensive effect of beta-blockers. May reduce the diuretic effect of furosemide.
Caffeine enhances the absorption and action of cardiac glycosides, increases their toxicity. With the simultaneous use of beta-blockers, mutual suppression of therapeutic effects may be noted. In the case of joint administration of adrenergic bronchodilator drugs, additional stimulation of the central nervous system and the development of other additive toxic effects are possible.
Analogs
Tsefekon N analogs are Citramon Ultra, Nurofen Plus, Asprovit S, Aspirin-S, Aspinat plus, etc.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Tsefekon N
Reviews of Tsefekon N are mostly positive: the drug quickly and effectively relieves pain and reduces fever. Its additional advantage is the rectal method of administration, which guarantees a faster development of the effect and no stress on the digestive system.
Most patients estimate the cost of rectal suppositories as very affordable.
Rare messages of a negative nature contain complaints of individual intolerance to the components of the drug, which was manifested by the development of allergic reactions.
Price for Cefekon N in pharmacies
The approximate price for Tsefekon N is 107-134 rubles. for a pack of 10 suppositories.
Cefekon N: prices in online pharmacies
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Drug name Price Pharmacy |
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Cefekon N rectal suppositories 10 pcs. 74 RUB Buy |
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Cefekon N rectal suppositories. 10 pieces. 126 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
