Trekrezan
Trekrezan: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Trekrezan
ATX code: A13A
Active ingredient: oxyethylammonium methylphenoxiacetate (oxyethylammonium methylphenoxiacetate)
Producer: JSC Usolye-Sibirskiy Khimfarmzavod (Russia)
Description and photo update: 2018-27-07
Prices in pharmacies: from 305 rubles.
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Trekrezan is a drug of immunomodulatory, adaptogenic and general tonic action.
Release form and composition
Trekrezan is produced in the form of tablets: flat-cylindrical, white or white with a yellow or cream shade (10 pcs. In a contoured cell-free or cell packaging; 10, 20 or 50 pcs. In a glass jar with a plastic lid; in a cardboard box 2 or 5 cell-free, or 1, 2 or 5 cell packs, or 1 can).
Composition of 1 tablet Trekrezan:
- active substance: oxyethylammonium methylphenoxyacetate (trerezan) - 200 mg;
- additional components: calcium stearate (calcium stearic acid), milk sugar (lactose monohydrate), potato starch.
Pharmacological properties
Pharmacodynamics
Trekrezan belongs to the group of adaptogenic drugs. It stimulates the formation of α- and γ-interferons, activating the humoral and cellular links of immunity, has a positive effect on the immune status of the body, and helps to enhance the phagocytic activity of macrophages. Currently, the exact mechanism of action of oxyethylammonium methylphenoxyacetate remains uncertain.
The active substance of the drug, due to its immunological effects, helps to increase the body's endurance against the background of physical and mental stress, reduce the negative effects of various toxins, increase resistance to hypoxia, low and high temperatures and to any other adverse effects from the environment.
Trekrezan is also characterized by pronounced antitoxic properties used for poisoning with organic solvents, heavy metal salts, ethanol.
Pharmacokinetics
According to the available data, oxyethylammonium methylphenoxyacetate is characterized by high bioavailability and rapid metabolic transformation in the liver. The agent is excreted by the kidneys mainly in the form of glucuronides. With prolonged use, it does not accumulate in the body.
In adolescents 12-18 years old, the elderly, as well as in patients with renal and / or hepatic insufficiency, there is no significant change in the pharmacokinetics of this substance.
Indications for use
According to the instructions, Trekrezan is recommended for use in the complex treatment of the following diseases / conditions:
- acute respiratory viral infections (ARVI), influenza, colds (prevention / treatment) in order to increase immunity;
- poisoning with salts of heavy metals;
- alcohol withdrawal syndrome;
- secondary immunodeficiency states (including during the period of prolonged antibiotic therapy).
Also Trekrezan is used to increase physical and mental performance, prevent overwork, enhance the body's resistance to various stressful influences (overheating, hypothermia, hypoxia, etc.).
Contraindications
- age up to 12 years;
- impaired absorption of galactose and glucose, lactase deficiency, hereditary lactose intolerance;
- pregnancy;
- period of breastfeeding;
- hypersensitivity to any of Trekrezan's constituents.
The drug should be used with caution in the presence of diabetes mellitus.
Instructions for the use of Trekrezan: method and dosage
Trekrezan tablets are taken orally.
Recommended dosing regimen for adolescents over 12 years of age and adults:
- ARVI (for prophylaxis), increased immunity: 200 mg (1 tablet) per day, course - 7-14 days;
- colds, acute respiratory viral infections, influenza (as part of complex therapy), a period of heavy physical and high intellectual exertion (to improve performance), various stressful effects (to enhance resistance): on the first day - 600 mg (3 tablets) per day, then daily 200 mg (1 tablet) per day for 7 days; course duration - 8 days, the total dose of the drug is 2000 mg;
- alcohol withdrawal syndrome (to reduce the severity of its manifestations), poisoning with salts of heavy metals: daily 400-600 mg (2-3 tablets) per day for at least 5 days.
If necessary, after 1–2 months after the end of the admission, a second course is possible.
If after 3 days of using Trekrezan there is no improvement in well-being and the severity of the symptoms of the above conditions does not decrease, you should consult a specialist for advice.
Side effects
Against the background of drug treatment, in rare cases, the appearance of allergic reactions in the form of anaphylaxis, anaphylactic shock, hypersensitivity reactions, Quincke's edema is possible.
Overdose
Signs of intoxication resulting from an overdose of the drug have not been registered. If this condition is suspected, symptomatic treatment is recommended.
special instructions
With the development of ARVI, it is imperative to consult a doctor if the following disorders occur (since they may indicate a severe course of the disease):
- high fever (increased body temperature above 39 ° C);
- the presence of symptoms of acute respiratory illness and body temperature above 38.5 ° C for 3 days or more;
- increased body temperature, accompanied by shortness of breath, severe pain, seizures, impaired consciousness;
- temperature above 37.5 ° C for 14 days or more.
Influence on the ability to drive vehicles and complex mechanisms
During the period of use of Trekrezan tablets, there was no negative effect on the patient's ability to drive complex mechanisms and vehicles.
Application during pregnancy and lactation
Pregnant and breastfeeding women are contraindicated to use Trekrezan, since the safety profile of the drug has not been studied in this category of patients.
Pediatric use
It is contraindicated to take Trekrezan to children under 12 years old, since there is no information confirming the safety and effectiveness of its use in this group of patients.
Drug interactions
No undesirable interaction of the drug with other drugs has been recorded.
Analogs
There is no information about Trekrezan's analogues.
Terms and conditions of storage
Store in a dark, dry place out of reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Trekrezan
Reviews about Trekrezan are quite controversial. Many users who have taken the drug consider it an effective remedy that strengthens the immune system, reduces the severity of symptoms of colds and SARS, increases the body's endurance and performance, and improves well-being against the background of stress and overstrain.
However, there are also many reviews that indicate the absence of a positive result from the use of the drug or its very weak effect. In some cases, users even notice a worsening of their condition after taking Trekrezan with ARVI. The development of adverse reactions is rare.
Price for Trekrezan in pharmacies
The price of Trekrezan can be approximately: 10 pcs. in the package - 205-290 rubles, 20 pcs. - 420-500 rubles.
Trekrezan: prices in online pharmacies
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Drug name Price Pharmacy |
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Trekrezan 200 mg tablets 10 pcs. 305 RUB Buy |
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Trekrezan tablets 200mg 10pcs 381 r Buy |
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Trekrezan 200 mg tablets 20 pcs. 535 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
