Sinokrom forte
Sinokrom forte: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Synocrom forte
ATX code: M09AX
Active ingredient: sodium hyaluronate
Producer: Kroma Pharma GmbH (Austria)
Description and photo update: 28.11.2018
Prices in pharmacies: from 5917 rubles.
Buy
Sinokrom forte is a synovial fluid substitute.
Release form and composition
The drug is produced in the form of a solution for intra-articular administration: a viscoelastic, transparent 2% aqueous solution (2 ml in a sterile-packed disposable syringe, ready for use; in a package of 1 or 3 syringes and instructions for use of Sinokrom forte).
1 ml of the preparation contains:
- active substance: stabilized sodium hyaluronate with a molecular weight of approximately 2.1 million daltons (Da) - 20 mg;
- additional components: sodium phosphate monohydrate, sodium carbonate, sodium chloride, sodium phosphate dihydrate, water for injection.
Sterilization of the solution is carried out in a ready-to-use syringe with high pressure steam.
Pharmacological properties
Pharmacodynamics
Sinokrom forte is a sterile, stabilized, isotonic, pyrogen-free solution that provides the restoration of the viscoelastic properties of the synovial fluid.
All synovial joints contain viscoelastic sodium hyaluronate. This substance is an active ingredient of Sinokrom forte. Thanks to the lubricating and shock-absorbing properties of the active substance, the drug reduces pain, increases the mobility of the joint, contributing to its normal, painless movement.
Against the background of degenerative diseases of the joints (osteoarthritis) or with post-traumatic changes in the latter, there is a significant decrease in the viscoelasticity of the synovial fluid, which leads to an increase in the mechanical load on the joints and activation of the processes of regeneration of the articular cartilage (manifested by limited joint mobility and pain symptoms during exercise). Intra-articular administration of highly purified stabilized sodium hyaluronate exhibiting optimized viscoelastic properties improves joint lubrication.
Indications for use
Sinokrom forte is recommended for use in pain and limitation of mobility due to degenerative or traumatic changes in joints containing synovial fluid.
Contraindications
The use of the drug is contraindicated in the presence of hypersensitivity to any of its components.
Since the solution is administered intraarticularly, patients with bacterial arthritis should refrain from using the drug in order to avoid possible complications. The attending physician should be informed about all immunological and other possible consequences of the use of biological agents.
Sinokrom forte, instructions for use: method and dosage
The drug is intended exclusively for intra-articular administration.
Before the procedure, it is required to remove the ready-to-use syringe from the sterile packaging, remove the rubber cap from it and put the appropriate-sized needle on the syringe cannula until it is tightly connected. Please note that the needle is not included in the delivery. The injection site must be treated with a disinfectant that contains alcohol. Intra-articular injection of the drug should be carried out under aseptic conditions by a specialist doctor. During the injection of the solution, the syringe should be held in such a position that the stop hole is at the back.
The course of therapy for Sinokrom Forte consists of 3 injections, made with an interval of 7 days between injections. Depending on the severity of the lesion, the effect of treatment can be observed up to 12 months. Simultaneous therapy of several joints is allowed, repeated courses are possible.
Side effects
When using the drug, local symptoms such as redness, fever, pain, and swelling may occur. To prevent the development of these side effects, it is recommended to apply an ice pack to the affected joint for 5-10 minutes. If these manifestations are pronounced and accompanied by severe pain, the solution must be removed from the affected joint.
Against the background of the use of the drug, isolated cases of the appearance of allergic (rash, itching, urticaria) and anaphylactic reactions were recorded.
Overdose
Data not specified.
special instructions
The drug contained in the syringe is for single use only. Resterilization is prohibited.
Do not use the syringe if its sterile packaging is open or damaged, or its cap is damaged or open.
Application during pregnancy and lactation
The efficacy and safety of the drug during pregnancy have not been studied.
There is no information on the use of Sinokrom forte during lactation.
Pediatric use
The use of the drug in patients under 18 years of age has not been investigated.
Drug interactions
There is currently no data on the incompatibility of the drug with other solutions for intra-articular administration.
Analogs
Analogues of Sinokrom forte are: Gialgan Phidia, Sinvisk, Sinokrom, Suplazin, Fermatron C, Ostenil, Hialubrix, Ost Tendon, Go-on, Dyuralan.
Terms and conditions of storage
Store out of the reach of children at a temperature not exceeding 25 ° C (do not freeze).
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Sinokrome Fort
Reviews about Sinokrom Fort are mostly positive. Many patients note that after the course of therapy, the joint (as a rule, the remedy was used to treat knee joints) began to function normally, the pain and discomfort arising from walking disappeared, and the swelling disappeared. According to reviews, the procedure for administering the solution is not very painful and lasts no more than 10 minutes. The duration of the effect of the drug is individual for each patient and depends on the severity of degenerative-dystrophic changes in the joint. After administration of the drug, patients are advised to take care of the joint for several days and not to expose it to high loads. Some patients find that after using the product, the likelihood of the disappearance of the need for joint prosthetics increases.
The disadvantages of the drug, almost all refer to its high cost. There are no complaints about adverse reactions.
The price of Sinokrom Fort in pharmacies
The price for Sinokrom Fort can be 4,100–6600 rubles per package containing 1 disposable syringe with 2 ml of 2% solution for intra-articular administration.
Sinokrom forte: prices in online pharmacies
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Drug name Price Pharmacy |
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Sinokrom forte 2% solution for intra-articular administration 2 ml 1 pc. RUB 5917 Buy |
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Sinokrom forte solution for intravenous joint entered 2% 2ml RUB 6176 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
