Sialor rino
Sialor Rino: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Sialor Rhino
ATX code: S01GA04
Active ingredient: oxymetazoline (oxymetazoline)
Producer: JSC "PFK Obnovlenie" (Russia)
Description and photo updated: 22.11.2018
Prices in pharmacies: from 71 rubles.
Buy
Sialor rino is a local drug with a vasoconstrictor effect used in ENT practice.
Release form and composition
Dosage form Sialora rino - nasal drops: transparent, colorless or somewhat colored (0.01% - in a cardboard box of 2 or 5 dropper tubes with a valve, 1 ml each; 0.025% - in a cardboard box of 2 or 5 dropper tubes with a valve 2 ml; 0.05% - in a cardboard box 1 polymer ampoule of 10 ml, complete with a dark glass bottle with a spray nozzle).
Composition 1 ml:
- active substance: oxymetazoline hydrochloride - 0.1; 0.25 or 0.5 mg;
- auxiliary components (0.1 / 0.25 / 0.5 mg): benzalkonium chloride - 0.1 / 0.15 / 0.15 mg; edetate disodium (Trilon B) - 0.5 / 0.5 / 0.5 mg; sodium hydroxide (0.1 M sodium hydroxide solution) - up to pH 6–7; sodium dihydrogen phosphate dihydrate - 1.29 / 1.29 / 1.29 mg; sodium hydrogen phosphate dodecahydrate - 1.76 / 1.76 / 1.76 mg; purified water - up to 1/1/1 ml.
Pharmacological properties
Pharmacodynamics
Oxymetazoline has a vasoconstrictor effect. Belongs to the group of alpha-adrenostimulants for local use.
When administered intranasally, the drug helps to reduce swelling of the mucous membrane of the upper respiratory tract. This opens the mouth of the paranasal sinuses and Eustachian tubes and facilitates nasal breathing.
The action of Sialor Rino after application develops within five minutes, its duration is 8-12 hours.
Pharmacokinetics
Oxymetazoline, when applied topically, is practically not absorbed.
Indications for use
- acute respiratory diseases accompanied by a runny nose;
- allergic rhinitis;
- vasomotor rhinitis;
- inflammation of the paranasal sinuses, eustachitis, otitis media (in order to restore drainage);
- carrying out diagnostic manipulations in the nasal passages (in order to eliminate edema).
Contraindications
Absolute:
- dry (atrophic) rhinitis;
- condition after transsphenoidal hypophysectomy;
- angle-closure glaucoma;
- the use of monoamine oxidase inhibitors during the previous 14 days and the same period after their withdrawal;
- age up to 1 year or 6 years (drops 0.025% or 0.05%, respectively);
- individual intolerance to the components of the drug.
Relative (Sialor Rino is prescribed under medical supervision):
- pheochromocytoma;
- combined use with tricyclic antidepressants and bromocriptine;
- chronic renal failure;
- diseases of the cardiovascular system, including tachycardia, arterial hypertension, chronic heart failure, ischemic heart disease, arrhythmias;
- disorders of carbohydrate metabolism (diabetes mellitus);
- hyperplasia of the prostate (urinary retention);
- dysfunction of the thyroid gland (hyperthyroidism);
- pregnancy and the period of breastfeeding.
Instructions for use of Sialor Rino: method and dosage
Sialor Rino is applied intranasally into each nasal passage 2 to 3 times a day.
Recommended single dose:
- children under 1 year old (0.01% solution): up to 4 weeks of life - 1 drop each; from the fifth week to 12 months - 1-2 drops;
- children 1-6 years old (0.025%): 1-2 drops each;
- children from 6 years old and adults (0.05%): 1-2 drops each.
It is not recommended to use Sialor Rino for more than 7 days. With prolonged / frequent use of the drug, the feeling of nasal congestion may worsen / reappear. If these symptoms appear, you need to cancel the drug and seek medical advice.
Side effects
Possible side reactions: dryness / burning of the mucous membranes of the nasal cavity, dryness of the mucous membranes of the mouth and throat, sneezing, an increase in the volume of secretions released from the nose, reactive hyperemia (a strong feeling of nasal congestion after the effect of the drug has passed).
Adverse reactions that are caused by the systemic action of Sialora rino: headache, sedation, increased blood pressure, palpitations, dizziness, irritability, nausea, exanthema, insomnia, tachycardia, increased anxiety, visual impairment (if the solution gets into the eyes), disturbances sleep (when using Sialor Rino in children).
Disorders associated with long-term use: tachyphylaxis, reactive hyperemia and atrophy of the nasal mucosa.
Benzalkonium chloride (preservative), which is part of Sialora Rino, can lead to swelling of the nasal mucosa. In this case, the drug is canceled.
Overdose
The main symptoms: tachycardia, nausea, depression of the central nervous system, increased blood pressure.
Therapy: symptomatic.
special instructions
In cases where after using Sialor Rino for three days, there is no improvement / symptoms intensify, you need to consult a specialist.
Avoid contact with the eyes.
To prevent the spread of infection, the drug must be used individually.
Influence on the ability to drive vehicles and complex mechanisms
When using Sialora Rino in high dosages, it is possible to develop disorders that can reduce the ability to drive vehicles (tachycardia, increased blood pressure, depression of the central nervous system).
Application during pregnancy and lactation
According to the instructions, Sialor Rino during pregnancy / lactation can be used after the doctor evaluates the ratio of the expected benefit with the possible risk.
Pediatric use
Contraindication to the appointment of Sialor Rino for children:
- 0.025% - up to 1 year;
- 0.05% - up to 6 years.
With impaired renal function
Sialor rino with chronic renal failure should be used under medical supervision.
Drug interactions
Possible interactions:
- monoamine oxidase inhibitors (including the period after their withdrawal for 14 days), tricyclic antidepressants: blood pressure may increase;
- local anesthetic drugs: their absorption slows down, the effect is lengthened;
- other vasoconstrictor drugs: the likelihood of side effects increases.
Analogs
Analogs of Sialor Rino are: Rinostop Extra, Vicks Active Sinex, Afrin, Noxprey, Nazivin, Nesopin, Oxyfrin, Nazosprey, Oxymetazoline, Nazol.
Terms and conditions of storage
Store in a place protected from light at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
After opening the bottle, Sialor Rino can be used for 14 days.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Sialor Rino
According to reviews, Sialor Rino has a quick effect. Also, among the advantages, they note the low cost, convenient packaging, the absence of discomfort during use and the possibility of using it in the treatment of children. Of the shortcomings, they indicate a short shelf life after opening, as well as a short period during which the drug can be used.
Price for Sialor Rino in pharmacies
The approximate price for Sialor Rino is:
- 0.01% (5 tubes 1 ml each): 101-106 rubles;
- 0.025% (5 dropper tubes, 2 ml each): 97-116 rubles;
- 0.05% (1 ampoule of 10 ml): 103-109 rubles.
The official website of the manufacturer is Sialor Rino for children.
Sialor Rino: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Sialor rino 0.01% nasal drops 1 ml 5 pcs. RUB 71 Buy |
|
Sialor rino 0.025% nasal drops 2 ml 5 pcs. RUB 78 Buy |
|
Sialor rino 0.05% nasal spray 10 ml 1 pc. 82 RUB Buy |
|
Sialor Reno nasal drops. 0.01% 1ml 5 pcs. 127 RUB Buy |
|
Sialor rino nasal spray. 0.05% 10ml RUB 160 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
