Rimecor - Instructions For Use, Reviews, Price, Tablet Analogues

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Rimecor - Instructions For Use, Reviews, Price, Tablet Analogues
Rimecor - Instructions For Use, Reviews, Price, Tablet Analogues

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Video: Rimecor - Instructions For Use, Reviews, Price, Tablet Analogues
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Rimecor: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Application during pregnancy and lactation
  1. 10. Use in childhood
  2. 11. In case of impaired renal function
  3. 12. For violations of liver function
  4. 13. Drug interactions
  5. 14. Analogs
  6. 15. Terms and conditions of storage
  7. 16. Terms of dispensing from pharmacies
  8. 17. Reviews
  9. 18. Price in pharmacies

Latin name: Rimecor

ATX code: C01EB15

Active ingredient: trimetazidine (trimetazidine)

Producer: MAKIZ-PHARMA CJSC (Russia)

Description and photo update: 2019-20-08

Prices in pharmacies: from 101 rubles.


Film-coated tablets, Rimecor
Film-coated tablets, Rimecor

Rimecor is a drug that has an antihypoxic effect, normalizing the energy metabolism of cells under conditions of hypoxia or ischemia.

Release form and composition

Dosage form - film-coated tablets: round, convex on both sides, pink; core - from white to almost white (10 pcs. in blisters, in a cardboard bundle 1, 2, 3 or 6 packs; 30 pcs. in blister packs, in a cardboard bundle 1 or 2 packs; 60 pcs.. in polymer cans, in a cardboard box 1 can).

Active ingredient: trimetazidine dihydrochloride - 20 mg in 1 tablet.

Additional components: magnesium stearate, ludipress LCE (povidone, lactose monohydrate), colloidal silicon dioxide (aerosil), lactose monohydrate, croscarmellose sodium.

The composition of the film shell: macrogol 4000 (polyethylene glycol 4000), titanium dioxide, talc, hypromellose (hydroxypropyl methylcellulose), azorubin dye (E122).

Pharmacological properties


The active ingredient of Rimecor is trimetazidine, a substance that has an antianginal and antihypoxic effect, which improves the metabolism of the myocardium and neurosensory organs under ischemic conditions.

Trimetazidine directly affects the neurons and cardiomyocytes of the brain, thereby optimizing their metabolism and function. Its cytoprotective effect is explained by the ability to increase the energy potential, activate oxidative decarboxylation and rationalize oxygen consumption (enhance aerobic glycolysis and block fatty acid oxidation). Rimecor maintains myocardial contractility, prevents a decrease in the intracellular content of phosphorus creatine and adenosine triphosphate.

Under conditions of acidosis, trimetazidine prevents the accumulation of calcium and sodium in cardiomyocytes, normalizes the functioning of membrane ion channels and the intracellular content of potassium ions. Reduces intracellular acidosis and increased phosphate levels due to reperfusion and myocardial ischemia. It prevents the activation of neutrophils in the ischemic zone, prevents the damaging action of free radicals, increases the duration of the electric potential, preserves the integrity of cell membranes, reduces the release of creatine phosphokinase from cells, and reduces the severity of ischemic myocardial damage.

With angina pectoris, trimetazidine reduces the frequency of attacks, as a result of which the need for nitrates decreases. After 2 weeks of regular use, exercise tolerance increases, blood pressure drops decrease. In patients taking Rimecor, tinnitus and dizziness decrease, hearing and vestibular test results improve.

In vascular pathology of the eyes, trimetazidine helps to restore the functional activity of the retina.


Trimetazidine, entering the body in the form of tablets, is rapidly and almost completely absorbed from the gastrointestinal tract. Its bioavailability reaches 90%. The maximum plasma concentration is observed after about 2 hours and is about 55 ng / ml after a single dose of 20 mg.

The drug is characterized by a low binding to plasma proteins - 16%. Easily penetrates histohematogenous barriers.

It is excreted by the kidneys, and in unchanged form ~ 60%. The half-life is 4.5-5 hours.

Indications for use

  • Ischemic heart disease (as part of complex therapy for the prevention of angina attacks);
  • Vertigo of vascular origin;
  • Chorioretinal vascular disorders;
  • Cochleo-vestibular disorders of an ischemic nature, such as tinnitus, dizziness, hearing impairment.


  • Severe liver dysfunction;
  • Renal failure (creatinine clearance less than 15 ml / minute);
  • Age under 18;
  • Pregnancy and lactation;
  • Glucose-galactose malabsorption, lactose intolerance or lactase deficiency;
  • Hypersensitivity to any component of the drug.

Instructions for the use of Rimecor: method and dosage

Rimecor should be taken orally with food.

Adult patients are prescribed 1 tablet 2-3 times a day.

The duration of treatment in each case is determined individually.

Side effects

  • From the digestive system: often (more than 1/100 and less than 1/10) - abdominal pain, nausea, dyspepsia, diarrhea, vomiting;
  • From the side of the cardiovascular system: rarely (more than 1/10 000 and less than 1/1000) - hot flushes to the skin of the face, orthostatic hypotension;
  • From the side of the central nervous system: often - dizziness, headache, asthenia; very rarely (less than 1/10 000) - extrapyramidal disorders (rigidity, tremor, akinesia), reversible after drug withdrawal;
  • Skin and subcutaneous tissue disorders: often - rash, urticaria, itching.


To date, no cases of overdose have been reported.

special instructions

According to the instructions, Rimecor is not intended to relieve angina attacks, but is used to prevent them.

Trimetazidine is not indicated for the initial course of therapy for unstable angina and myocardial infarction.

If the nature of the attacks of angina pectoris changes, as well as when they become more frequent, you should consult a doctor to review and adapt the course of treatment.

In patients with coronary artery disease, Rimecor significantly reduces the daily requirement for nitrates.

The drug, as a rule, does not affect the speed of psychophysical reactions and the ability to concentrate.

Application during pregnancy and lactation

Rimecor is contraindicated in pregnant women and breastfeeding mothers.

Pediatric use

The drug is not used in pediatric practice for the treatment of children and adolescents under the age of 18.

With impaired renal function

It is forbidden to take Rimecor to patients with renal insufficiency (if creatinine clearance is below 15 ml / min).

For violations of liver function

Patients with concomitant severe hepatic impairment are prohibited from taking Rimecor.

Drug interactions

There is no information on the interaction of Rimecor with other medicinal products.


Analogs of Rimecor are: Angiosil retard, Trimetazidin, Trimet, Triducard, Vasomag, Bravadin, Ezafosfina, Idrinol, Kudesan, Cardionat, Preductal MV, Dibikor, Antisten, Histochrome, Coraxan, Antisten MV, Mildronat, Mexinmethonidin, Ribbon, Ethoxidol, Deprenorm-MV, Presidin, Preductal OD, Precard, Trimetazid, Trimetazidine MV, Trimetazidine MV-Teva, Trimitard MV.

Terms and conditions of storage

Store in a place protected from light and moisture, out of the reach of children, at temperatures up to 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Rimecor

Reviews about Rimecor are mostly positive. Both doctors and the patients themselves note the rapid action of the drug and the excellent effect, especially in case of vestibular disorders of an ischemic nature (such as dizziness, tinnitus and hearing impairment). Good results of the agent were also noted in the prevention of angina attacks in patients with ischemic heart disease.

Patients attribute additional advantages to Rimecor's good tolerance and low cost.

Price for Rimecor in pharmacies

Depending on the pharmacy chain where the drug is sold, the price for Rimecor can vary from 130 to 250 rubles. for one pack of 30 tablets.

Rimecor: prices in online pharmacies

Drug name



Rimecor 20 mg film-coated tablets 30 pcs.

RUB 101


Rimecor tablets p.o. 20mg 30 pcs.

170 RUB


Rimecor MV 35 mg film-coated tablets of prolonged action 60 pcs.

214 r


Anna Kozlova
Anna Kozlova

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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