Ranavexim
Ranavexim: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Ranaveksim
ATX code: D06BA05
Active ingredient: sulfanilamide (Sulfanilamide)
Manufacturer: LLC "Avexima Siberia" (Russia); LLC "YuzhFarm" (Russia)
Description and photo update: 2019-03-12
Prices in pharmacies: from 41 rubles.
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Ranavexim is a broad-spectrum antibacterial drug for external use.
Release form and composition
The drug is produced in the form of a powder for external use: crystalline loose mass of white or almost white color (in polymer cans / jars with a dispenser of 2, 5 or 10 g, in a cardboard box 1 can; 2, 5 or 10 g in heat-sealable bags, in a cardboard box 1, 2, 3, 4, 6, 8, 10 or 20 packages and instructions for use of Ranavexim).
The powder contains the active ingredient: sulfanilamide (streptocide) - 2, 5 or 10 g.
Pharmacological properties
Pharmacodynamics
Ranavexim is an antibacterial drug for external use. Its active substance is sulfonamide (streptocide), it has a wide spectrum of antimicrobial bacteriostatic activity. The mechanism of action of the drug is due to competitive antagonism between sulfanilamide and PABA (Para-aminobenzoic acid), inhibition of dihydropteroate synthetase, which causes disruption of the synthesis of dihydrofolic and tetrahydrofolic acid. This leads to disruption of the synthesis of nucleic acids of pathogenic microflora.
The following gram-positive and gram-negative microorganisms are sensitive to sulfonamide: Shigella speciales (spp.), Clostridium spp., Actinomyces spp., Chlamydia spp., Escherichia coli, Vibrio cholera, Corynebacterium diphtheriaii, Bacillus gesthersia.
Indications for use
The use of Ranavexim is indicated as part of the complex therapy of purulent-inflammatory processes of soft tissues of various origins, including infected wounds and infected burns of I – II degree.
Contraindications
Absolute:
- diseases of the hematopoietic system, anemia, inhibition of bone marrow hematopoiesis;
- renal and / or hepatic impairment;
- chronic heart failure;
- porphyria;
- thyrotoxicosis;
- azotemia;
- congenital deficiency of glucose-6-phosphate dehydrogenase;
- period of pregnancy;
- breast-feeding;
- hypersensitivity to sulfonamides.
Ranavexim should be used with caution to treat children under 3 years of age.
Ranavexim, instructions for use: method and dosage
Powder Ranavexim is applied externally by applying directly to the surface of the lesion, and in the case of deep wounds, the drug is applied directly into their cavity.
The doctor determines the duration of the course of treatment, taking into account the characteristics of the disease, individual tolerance and therapeutic efficacy of the drug.
Recommended dosage:
- adults: single dose - 5 g, daily dose - 15 g;
- children over the age of 3 years: single and daily dose - 0.3 g.
Dressings should be done in 1–2 days.
If there is no dynamics of improvement in the condition or the appearance of new symptoms, you should consult a doctor.
Side effects
Against the background of the use of Ranavexim, there is a risk of developing such adverse events as: allergic reactions, nausea, vomiting, dyspepsia, headache, dizziness, leukopenia, cyanosis, agranulocytosis, crystalluria.
Overdose
Symptoms: drowsiness, fever, intestinal colic, nausea, vomiting, dizziness, headache, blurred vision, fainting, hematuria, depression, confusion, crystalluria; in cases of prolonged use of high doses - jaundice, megaloblastic anemia, thrombocytopenia, leukopenia.
Treatment: drinking plenty of fluids is indicated, with accidental ingestion - immediate gastric lavage.
special instructions
With the development of allergic reactions, immediate withdrawal of the drug is required.
Treatment with the drug is recommended to be accompanied by abundant use of alkaline drinks.
With long-term treatment with sulfonamides, it is necessary to systematically monitor the blood picture, the functional state of the kidneys and liver.
If necessary, combination therapy involves the simultaneous use of oral antimicrobial agents.
Influence on the ability to drive vehicles and complex mechanisms
Due to the fact that the undesirable effect of the drug on the nervous system can cause dizziness, during the period of treatment, patients should be careful when performing potentially hazardous activities, including driving or working with complex mechanisms.
Application during pregnancy and lactation
The use of Ranavexim is contraindicated during gestation and breastfeeding.
Pediatric use
It is recommended to use Ranavexim powder with caution for the treatment of children under 3 years of age.
With impaired renal function
The use of Ranavexim is contraindicated in renal failure.
For violations of liver function
The use of Ranavexim is contraindicated in hepatic insufficiency.
Drug interactions
With the simultaneous use of Ranavexim with myelotoxic agents, its hematotoxicity increases.
If it is necessary to combine sulfonamide with any other medications, it is recommended that you consult your doctor.
Analogs
Analogs of Ranavexim are Streptocid (soluble liniment externally, powder externally, ointment externally), Streptocide ointment, Streptocid-LekT, Bactoderm, Baneocin, Sulfargin, Fusimet, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C in a dark place.
The shelf life is 5 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Ranavexim
Most of the reviews about Ranavexim is positive. Many patients are very satisfied with the action of the drug and use it as an ambulance in the treatment of skin lesions of various localization and genesis. They note that applying the powder to the wound surface prevents wound infection, dries out wet surfaces and promotes healing. The advantages include low cost, convenient form of release - cans with a dispenser, long shelf life.
There are negative reviews, they indicate the weak efficacy of the drug, which is presumably associated with the low content of streptocide in the powder, as well as the formation of dense crusts as a result of its combination with the ichor.
The price of Ranavexim in pharmacies
The price of Ranavexim for a package containing 1 can (5 g) with a dispenser can range from 83 rubles.
Ranavexim: prices in online pharmacies
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Drug name Price Pharmacy |
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Ranavexim powder 5 g 1 pc. 41 rbl. Buy |
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Ranavexim powder for outdoor use approx. 5g RUB 85 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
