Goldline Plus
Instructions for use:
- 1. Pharmacological action
- 2. Indications for use
- 3. Method of administration and dosage
- 4. Side effects
- 5. Contraindications
- 6. Overdose
- 7. Analogs
- 8. Additional information
Prices in online pharmacies:
from 1289 rub.
Buy
Goldline Plus is a drug for the treatment of obesity. The preparation contains sibutramine and microcrystalline cellulose. According to the content of sibutramine in one capsule, the drug is available in two dosages - 10 mg and 15 mg.
Goldline Plus is a combination drug. Sibutramine is a potent substance, however, in combination with microcrystalline cellulose, it does not belong to the list of potent drugs and is available on a prescription form 107.
pharmachologic effect
Sibutramine and its metabolites affect the reuptake of neurotransmitters - serotonin and norepinephrine in the synaptic cleft, thereby prolonging the feeling of satiety (dulling the feeling of hunger) and increasing heat production (increasing thermogenesis). As a result of numerous clinical studies, it has been shown that while taking sibutramine, the amount of food consumed is reduced by 20%, and the calorie content by 25%. At the same time, against the background of increased thermogenesis, about 100 kcal per day are additionally consumed.
With a decrease in body weight while taking Goldline Plus, there is an increase in high-density triglycerides (HDL) in the blood, a decrease in triglycerides, total cholesterol, low-density lipoproteins (LDL) and uric acid.
Sibutramine does not have a narcotic effect; addiction does not develop when taking the drug.
Microcrystalline cellulose is an enterosorbent, has sorption properties and a nonspecific detoxification effect. It binds and removes from the body various microorganisms, their metabolic products, toxins of exogenous and endogenous nature, allergens, xenobiotics, as well as an excess of certain metabolic products and metabolites responsible for the development of endogenous toxicosis.
Indications for use
Indications for use of Goldline Plus are:
- Obesity with a BMI (body mass index) of more than 30 kg / m 2
- Overweight a BMI over 27 kg / m 2 in the presence of comorbidities (hypertension, diabetes mellitus type 2)
Method of administration and dosage
Goldline Plus is taken one capsule a day in the morning. Treatment begins with a lower dosage of 10 mg. If, within 4 weeks of admission, a decrease in body weight of more than 2 kg is not achieved, they switch to a higher dosage - 15 mg.
The effect of the drug develops gradually during the first month, the maximum effect is observed after 3 months of continuous use. If you skip taking the drug, you should not take a double dose the next day.
Goldline Plus is recommended to be taken in a course of 6 months, since during this time not only a significant decrease in body weight is achieved, but also correct eating habits are formed. Due to this, the partial effect after discontinuation of the drug lasts up to 2 years. The maximum duration of admission should not exceed 1 year, since there are no data from clinical studies on the effectiveness and safety of longer use.
Reception of Goldline Plus should be discontinued if the patient responds poorly to therapy - if, after three months of use, the body weight loss is less than 5%.
It should be remembered that Goldline Plus is used only in complex therapy along with hypocaloric nutrition and physical activity.
Side effects
Basically, side effects when taking Goldline Plus are observed during the first month of admission, they are not severe, do not require pharmacological correction and go away on their own after a month.
Mainly, the following side effects are observed: dry mouth, insomnia, headache, dizziness, anxiety, increased heart rate, increased blood pressure, loss of appetite, constipation, nausea, increased sweating.
Contraindications
- Established hypersensitivity to sibutramine or to other components of the drug;
- The presence of organic causes of obesity (for example, hypothyroidism);
- Serious eating disorders - anorexia nervosa or bulimia nervosa;
- Mental illness;
- Gilles de la Tourette's syndrome (generalized tics);
- Concomitant use of MAO inhibitors (eg, phentermine, fenfluramine, dexfenfluramine, ethylamphetamine, ephedrine)
- Cardiovascular diseases (in history or at present): ischemic heart disease (myocardial infarction (MI), angina pectoris); chronic heart failure in the stage of decompensation, occlusive peripheral arterial disease, tachycardia, arrhythmia, cerebrovascular disease (stroke, transient cerebrovascular accident);
-
Uncontrolled arterial hypertension (blood pressure (BP) above
145/90 mm Hg) (see also the section "Special instructions");
- Closed-angle glaucoma;
- Thyrotoxicosis;
- Severe violations of liver and / or kidney function;
- Benign prostatic hyperplasia;
- Pheochromocytoma;
- Established pharmacological, drug or alcohol dependence;
- Pregnancy and breastfeeding period;
- Age under 18 and over 65.
Goldline Plus should not be used during pregnancy and lactation, since there is no clinical data on the safety of the effects of sibutramine on the fetus and infant.
Overdose
There are limited data on drug overdose. Most often, tachycardia, dizziness, headache, and increased blood pressure are observed. There is no specific treatment or antidote. In case of an overdose, you must stop taking the drug for a while and notify your doctor about it.
Analogs
Reduxin is a complete analogue in composition.
Additional Information
According to the instructions, Goldline Plus should be taken in the event that independent attempts to reduce weight have not brought tangible results - if within three months the weight loss is less than 5 kg.
However, in some cases, doctors recommend starting treatment with a combination of diet and appetite suppressants, such as Goldline Plus, so that at the initial stage, restrictions on food intake are easier for the patient and correct eating habits are initially formed.
Goldline Plus: prices in online pharmacies
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Drug name Price Pharmacy |
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Goldline Plus 10 mg + 158.5 mg capsules 30 pcs. 1289 RUB Buy |
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Goldline Plus capsules 10mg + 158.5mg 30 pcs. 1430 RUB Buy |
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Goldline Plus 15 mg + 153.5 mg capsules 30 pcs. 1600 RUB Buy |
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Goldline Plus 10 mg + 158.5 mg capsules 90 pcs. 2026 RUB Buy |
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Goldline Plus 10 mg + 158.5 mg capsules 60 pcs. RUB 2117 Buy |
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Goldline Plus capsules 15mg + 153.5mg 30 pcs. 2211 RUB Buy |
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Goldline Plus capsules 10mg + 158.5mg 60 pcs. 2341 RUB Buy |
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Goldline Plus 15 mg + 153.5 mg capsules 60 pcs. 3558 RUB Buy |
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Goldline Plus capsules 15mg + 153.5mg 60 pcs. 3753 RUB Buy |
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Goldline Plus 15 mg + 153.5 mg capsules 90 pcs. 3803 RUB Buy |
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Goldline Plus capsules 15mg + 153.5mg 90 pcs. RUB 5108 Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
