Glycyphone
Glycifon: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Glyciphon
ATX code: L01XX
Active ingredient: diglycidyl methylphosphonate (Diglycidyl methylphosphonate)
Manufacturer: JSC "Tatkhimfarmpreparaty" (Russia)
Description and photo update: 20.05.2019
Prices in pharmacies: from 9882 rubles.
Buy
Glycifon is an antineoplastic agent for external use.
Release form and composition
Dosage form - ointment for external use 30%: from greenish-brown or yellow-brown to yellow with a specific odor (in a cardboard box 1 bottle of brown glass containing 10 g of ointment, and instructions for the use of Glycifon).
The composition of 100 g of ointment includes:
- active substance: glycyphon (diglycidyl methylphosphonate) - 30 g;
- auxiliary components: anhydrous lanolin - 60 g; petroleum jelly - 10 g.
Pharmacological properties
Pharmacodynamics
Glycifon has antiseptic, antitumor and cytostatic properties. With precancerous pathologies and skin tumors, it exhibits a contact effect.
The antimitotic effect of the drug, which is especially pronounced in the acidic environment of the tumor tissue, explains its ability to selectively inhibit metabolism in blastomatous cells.
Pharmacokinetics
The drug has no side effects of skin resorptive effects.
Indications for use
- first stage squamous cell carcinoma of the skin;
- basal cell carcinoma, including relapses after radiation or surgical therapy;
- senile keratosis;
- Bowen's disease.
Contraindications
- pregnancy and lactation;
- individual intolerance to the components of the drug.
Glycifon, instructions for use: method and dosage
Ointment Glycifon is intended for external use.
Before applying the drug, the skin in the growth zone of keratosis or neoplasms is lubricated with a swab moistened with alcohol. After that, depending on the size of the focus, from 0.8 to 2 g of ointment is applied under a gauze napkin, fixed with a plaster. The lesion and the surrounding skin are wiped with alcohol at each dressing, and the necrotic tissue is removed. The drug is applied once a day (up to 24 hours) until the tumor tissue is completely destroyed.
The duration of therapy is set on an individual basis, depending on the size of the lesion and its location.
The number of applications, depending on the pathology, is:
- recurrent tumors, small-nodular forms of basaliomas in the nose and forehead: from 15 to 20;
- Bowen's disease, superficial basal cell carcinomas, ulcerative forms: from 10 to 15;
- senile keratoses: 5 to 10.
After the end of therapy, it is recommended to daily apply aseptic dressings with regenerating agents to the formed defect (until complete scarring).
Side effects
During the period of use of the drug, hyperemia, edema of the periorbital region, as well as pain and edema at the site of application of the ointment, may appear.
Overdose
There is no information.
special instructions
If side effects appear, it is necessary to take a break in therapy for 2-3 days. During this period, lotions should be done using an ointment containing glucocorticosteroids or a furacilin solution. Treatment is continued after a break. The physician may recommend reducing the daily exposure to 6 hours instead of 24 hours.
In order to reduce pain at the site of application, an ointment with anesthesin 5–10% can be applied to the focus at the same time.
Application during pregnancy and lactation
Ointment Glycifon is not prescribed during pregnancy / breastfeeding.
Drug interactions
There are no data on the interaction of Glycifon with other drugs.
Analogs
An analogue of Glycyphone is Glycyphone ointment 30%.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 20 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Glycyphone
According to a few reviews, Glycifon is a safe and effective drug used to treat baselioma.
The price of Glycifon in pharmacies
The approximate price for Glycifon (1 bottle with 10 g of ointment in the package) varies from 4599 to 6500 rubles.
Glycifon: prices in online pharmacies
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Drug name Price Pharmacy |
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Glycifon 30% ointment for external use 10 g 1 pc. RUB 9882 Buy |
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Glycifon ointment for planks. approx. 30% fl. 10g 12 630 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
