Ginocaps
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Ginocaps is a combined drug with antimicrobial, antiprotozoal and antifungal action, used in gynecology.
Release form and composition
The dosage form of the release of Ginocaps is vaginal capsules: soft gelatinous, elastic, with a seam, opaque, light brown, ovoid with a pointed end; content - oil suspension from dark yellow to light yellow with white inclusions and non-rancid odor; during storage, delamination of the mixture is permissible (5 pcs. in blisters, in a cardboard box 2 blisters).
Active ingredients in 1 capsule:
- metronidazole - 100 mg;
- miconazole nitrate - 100 mg.
Auxiliary components: beeswax - 144 mg; purified lecithin - 45 mg; purified water - 108 mg; sunflower oil - in the amount required to obtain a capsule weighing 1800 mg.
Sheath: glycerol - 134 mg; gelatin - 268 mg; methyl parahydroxybenzoate (E218) - 0.5 mg; titanium dioxide (E171) - 1.8 mg; propyl parahydroxybenzoate (E216) - 0.13 mg; dye sunset sunset yellow (E110) - 0.026 mg; purified water - 35 mg.
Indications for use
Ginocaps is prescribed for the local treatment of vaginitis of mixed etiology, which are simultaneously caused by Candida spp. and Trichomonas spp.
Contraindications
Absolute:
- liver failure;
- leukopenia, including anamnestic data;
- organic lesions of the central nervous system, including epilepsy;
- I trimester of pregnancy and the period of breastfeeding;
- age up to 12 years;
- individual intolerance to the components of the drug.
Relative (diseases / conditions in which caution is required when prescribing Ginocaps):
- diabetes;
- microcirculation disorders;
- II and III trimesters of pregnancy (before prescribing therapy, the doctor must correlate the expected benefit with the possible risk).
Method of administration and dosage
Ginocaps is applied intravaginally (deep into the vagina) in the evening before bedtime.
The therapy is carried out in combination with oral administration of metronidazole.
The daily dose is 1 capsule. The course is 10 days.
Side effects
- digestive system: diarrhea, nausea, vomiting, decreased appetite, change in taste, taste of metal in the mouth, abdominal pain of a spastic nature, constipation, diarrhea;
- genitourinary system: urine staining red-brown;
- hematopoietic system: leukocytosis / leukopenia;
- central nervous system: dizziness, headache;
- allergic reactions: itching of the skin, hives, rash;
- local reactions: irritation, itching, pain, burning of the vaginal mucosa, vaginal discharge (white, thick, mucous membranes; may have a faint odor), frequent urination; the sexual partner has a burning sensation / irritation of the penis.
special instructions
It is strictly forbidden to use alcohol during the course.
It is recommended to carry out simultaneous therapy for both sexual partners.
During the period of application of Ginokaps, the development of slight leukopenia may be observed, and therefore, at the beginning and at the end of therapy, it is advisable to monitor the blood picture (number of leukocytes).
It is recommended to abstain from sexual intercourse for the period of treatment.
Due to the possible immobilization of treponemas, TPI test results may be false positive.
If the use of Ginocaps leads to the appearance of adverse reactions from the nervous system, it is recommended to refuse to drive vehicles.
Drug interactions
Miconazole has a low systemic absorption, and therefore interactions with other drugs can only be due to metronidazole.
With the combined use of metronidazole with certain drugs / substances, the following effects may develop:
- disulfiram: additive effect, possible development of confusion (the combination is contraindicated);
- alcohol: the development of symptoms similar to disulfiram (characterized by cramping abdominal pain, nausea, vomiting, headache, skin flushing);
- non-depolarizing muscle relaxants (vecuronium bromide): the combination is not recommended;
- indirect anticoagulants: increasing their action (due to the likelihood of an increase in prothrombin time, a dose adjustment of these drugs may be required);
- cimetidine: suppression of the metabolism of metronidazole, which can lead to an increase in its serum concentration in the blood and an increase in the likelihood of adverse reactions;
- phenobarbital, phenytoin and other inducers of enzymes of microsomal oxidation in the liver: acceleration of the elimination of metronidazole, which can lead to a decrease in its plasma concentration in the blood;
- lithium preparations: an increase in the concentration of lithium (it is recommended to reduce their dose or completely cancel it for the period of therapy).
Analogs
Ginokaps analogs are: Klion-D 100, Neo-Penotran, Metromikon-Neo.
Terms and conditions of storage
Store in a place protected from light and moisture at a temperature of 15-25 ° C. Keep out of the reach of children.
The shelf life is 18 months.
Terms of dispensing from pharmacies
Dispensed by prescription.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
