Broncho-munal P

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Latin name: Broncho-munal P

ATX code: L03AX

Active ingredient: bacterial lysates [Klebsiella ozena or Abel's bacillus + Klebsiella pneumoniae or Friedlander's bacillus + Hemophilic influenza stick or Pfeifer's stick (Pfeifer's) + moraxella catarrhalis + pneumococcus + pyogenic streptococcus + green streptococcus + Staphylococcus aureus (Kaelebsiella lactobacillus) + Staphylococcus aureus pneumoniae + Haemophilus influenzae + Moraxella catarrhalis + Streptococcus pneumoniae + Streptococcus pyogenes + Streptococcus viridans + Staphylococcus aureus)]

Manufacturer: LEK d.d. (LEK dd) (Slovenia)

Description and photo update: 2019-08-07

Prices in pharmacies: from 469 rubles.

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Broncho-munal P is an immunostimulating agent of bacterial origin.

Release form and composition

The drug is produced in the form of capsules: size No. 3, gelatinous solid, opaque, white body, blue cap; the contents of the capsules are a pale beige powder (10 pcs. in a blister, in a cardboard box 1 or 3 blisters and instructions for the use of Broncho-Munal P).

1 capsule contains:

active ingredients: standardized lyophilisate of bacterial lysates (OM-85) - 20 mg, including lyophilized bacterial lysates - 3.5 mg (including Streptococcus pneumoniae, Haemophilus influenzae, Streptococcus pyogenes, Streptococcus viridans, Klebsiella ozaenae, Klebsiella pneumonia catarrhalis, Staphylococcus aureus);
additional components: magnesium stearate, propyl gallate (anhydrous), mannitol, sodium glutamate (anhydrous), pregelatinized starch;
capsule shell: titanium dioxide E171, gelatin, indigotin E132.

Pharmacological properties

Pharmacodynamics

Broncho-munal P has an immunostimulating effect, helping to increase immunity against respiratory tract infections.

After oral administration of the capsule, the bacterial lysate contained in it accumulates in group (generalized) lymphoid nodules or Peyer's patches of the mucous membrane of the gastrointestinal tract (GIT), localized primarily in the mucous membrane of the ileal wall. The antigen-presenting cells in Peyer's patches activated by bacterial lysate further stimulate B-lymphocytes - cells responsible for a specific immune response. The number of circulating B-lymphocytes increases, which causes an increase in the production of polyclonal antibodies, mainly serum immunoglobulin G (IgG) and immunoglobulin A (IgA), produced by the salivary glands and the mucous membrane of the respiratory tract.

Also, Broncho-munal P stimulates most of the leukocytes, which is expressed in an increase in the number of cells of the lymphoid and myeloid series, and a selective increase in the expression of receptors located on the surface.

Against the background of using the drug to fight against viruses and bacteria, the body's natural defense mechanisms are activated, leading to an increase in resistance to infections of the respiratory system. The drug reduces the frequency and duration of acute respiratory tract infections, and also reduces the risk of exacerbations of chronic bronchitis. This reduces the need for other drugs, including antibiotics.

Indications for use

Broncho-munal P 3.5 mg capsules are recommended for use in children aged 6 months to 12 years with the following diseases:

acute infections of the respiratory tract (as part of combination therapy);
recurrent respiratory tract infections and exacerbation of chronic bronchitis (for prevention).

Contraindications

age up to 6 months;
pregnancy and lactation;
sensitivity to any component of Broncho-munal P.

Broncho-munal P, instructions for use: method and dosage

The immunostimulating agent is taken orally in the morning on an empty stomach, 30 minutes before meals.

The recommended dosage of Broncho-munal P for children: 1 capsule once a day.

For children under 3 years of age, or if the child has difficulty swallowing the capsule, you can open it and mix the contents with a small amount of liquid (milk, tea or juice).

The recommended duration of taking the drug, depending on the indications:

prevention of recurrent infections of the respiratory tract and exacerbations of chronic bronchitis: 3 courses of 10 days are carried out, with a break between courses of 20 days;
acute respiratory tract infections (as part of complex treatment): taken before symptoms are relieved, the course should be at least 10 days; against the background of antibiotic therapy, it is required to use Broncho-Munal P in combination with antibacterial agents from the beginning of treatment; in the next 2 months for prophylaxis, you can take courses of 10 days at intervals of 20 days.

Side effects

The product is generally well tolerated. Most of the violations when taking it belong to the general category with moderate or moderately severe severity. The most common adverse effects are gastrointestinal upset, skin reactions and respiratory disorders.

Other side effects:

immune system: infrequently - hypersensitivity reactions (swelling, including swelling of the face; edema, including eyelids and face; itching, including generalized; generalized rash, peripheral edema, erythema, erythematous rash);
respiratory system: often - cough; infrequently - shortness of breath;
nervous system: with an unknown frequency - headache;
digestive system: often - abdominal pain, diarrhea; with an unknown frequency - vomiting, nausea;
skin and subcutaneous tissue: often - rash; with an unknown frequency - urticaria, angioedema;
general disorders: with an unknown frequency - fatigue, fever.

Overdose

Cases of intoxication as a result of an overdose of Broncho-munal P have not been recorded.

Given the composition of the drug and the results of animal toxicity studies, it is believed that overdose is unlikely.

special instructions

Children aged 6 months to 12 years, in order to avoid a possible risk of overdose, should not use Broncho-Munal 7 mg capsules intended for the treatment of adults.

Against the background of drug therapy, hypersensitivity reactions to its components may be observed. In case of persisting symptoms of individual intolerance to any components of Broncho-Munal P, including skin reactions, gastrointestinal disorders, unwanted effects from the respiratory system, you should immediately stop treatment and consult a specialist.

Influence on the ability to drive vehicles and complex mechanisms

The drug does not have a negative effect on the performance of potentially hazardous activities that require increased concentration of attention and high speed of psychomotor reactions.

Application during pregnancy and lactation

No negative effects on pregnancy have been found in animal studies.

Since the safety and efficacy of drug treatment have not been studied during pregnancy and lactation, the use of Broncho-munal P is contraindicated in pregnant and lactating women.

Pediatric use

The drug therapy is recommended for children aged 6 months to 12 years. Broncho-munal P is contraindicated in children under 6 months of age.

Drug interactions

With other medicinal substances / agents, the interaction of the drug was not recorded. Broncho-munal P can be used in combination therapy with other drugs, including antibiotics.

Analogs

Broncho-munal P analogs are Broncho-munal, Broncho-Vax for children, Broncho-Vax for adults, Ribomunil, Ismigen, Imudon, Uro-Vax, Actinolizat, Ebermin, Feligen, Tomitsid, etc.

Terms and conditions of storage

Store out of the reach of children at a temperature of 15-25 ° C.

The shelf life is 5 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Broncho-Munale P

On medical sites, reviews of Broncho-Munal P are quite common, and they are quite diverse. Many parents of young patients note that after a course of use of the drug in the preparatory period for kindergarten, constantly ill children were much less likely to be exposed to acute respiratory tract infections and more easily tolerated adaptation to a preschool. In their opinion, the drug helped to strengthen the immune system of babies, and if the children were still sick, they recovered much faster.

However, there are many reviews in which parents complain about the lack of a dramatic effect on strengthening the immune system in their children. And they indicate that children also often continued to get sick in kindergarten or school during the period of taking the drug, as before. Only the intervals between acute respiratory diseases became longer, and after the completion of treatment, the effect of the drug was not observed at all. At the same time, almost no one noted the development of adverse reactions.

In some reviews, the drug is recommended to be used only for the prevention of exacerbations of chronic bronchitis.

The disadvantage of the drug is considered by many to be its high cost.

Price for Broncho-munal P in pharmacies

On average, the price of Broncho-munal P 3.5 mg per package containing 10 capsules is 500 rubles, per package 30 pcs. - 1350 rubles.

Broncho-munal P: prices in online pharmacies

Drug name

Price

Pharmacy

Broncho-munal P 3.5 mg capsules 10 pcs.

469 r

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Broncho-munal p caps. 3.5mg n10

RUB 488

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Broncho-munal P 3.5 mg capsules 30 pcs.

1234 RUB

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Broncho-munal p caps. 3.5mg n30

1384 RUB

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Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!