Bificol
Bificol: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Bificol
ATX code: A07FA
Active ingredient: bifidobacteria bifidum (Bifidobacterium bifidum) + Escherichia coli (Escherichia coli)
Manufacturer: Biomed them. I. I. Mechnikova, JSC (Russia); Microgen FSUE, NPO (Russia)
Description and photo updated: 2019-27-08
Bifikol is a drug of the eubiotic group that normalizes the intestinal microflora.
Release form and composition
Dosage form - lyophilisate for preparation of suspension for oral administration: whitish-gray with a yellowish tinge, crystalline or porous mass with a specific odor; after dissolution in water, a cloudy suspension forms; the presence of small flakes is permissible (in multilayer sachets / vials for 5 doses, in a cardboard box 10, 20, 30, 40 or 50 sachets / vials and instructions for use of Bificol).
Active substances in 1 dose:
- Live Escherichia coli cells of strain M-17 - not less than 10 7;
- Living cells of B. bifidum 1 strain - not less than 10 7.
Auxiliary components in Bifikol: gelatin, sugar (sucrose), milk (substances of a protective drying medium).
Pharmacological properties
Pharmacodynamics
The therapeutic effect of Bifikol is manifested due to the antagonistic activity of live bifidum bacteria and Escherichia coli in relation to pathogenic and opportunistic intestinal microflora, including Salmonella (Salmonella), Shigella (Shigella), Proteus (Proteus), etc.
Stimulating local reparative processes in the intestine, the drug exhibits adjuvant and immunomodulatory activity of bacterial antigens, which affect the production of non-specific and specific defense factors, including local ones.
Indications for use
The use of Bifikol is advisable for dysbiosis of the gastrointestinal tract, including those developing against the background:
- Inflammatory diseases of the gastrointestinal tract (colitis, ulcerative colitis, enterocolitis);
- Intestinal infections (salmonellosis, dysentery, viral diarrhea).
The drug can also be prescribed during the recovery period after chemotherapy.
Contraindications
A contraindication to the use of Bifikol is the simultaneous therapy with antibiotic drugs.
Bifikol, instructions for use: method and dosage
The drug is recommended to be taken 30 minutes before meals, 2 times a day. Immediately before use, the lyophilisate should be diluted with boiled water at room temperature at the rate of 1 teaspoon of water for 1 dose.
Patients with high acidity 10 minutes before taking the medicine are recommended to drink half a glass of mineral water ("Essentuki No. 17", "Essentuki No. 14", "Borjomi") or sodium bicarbonate solution (half a teaspoon of soda per 200 ml of water).
The dosage of Bificol is determined based on the patient's age:
- Adults and children over 3 years old are recommended to take 3-5 doses of the drug 2 times a day;
- Children from 1 to 3 years old - 2-5 doses;
- Children from 6 months to 1 year old - 1 dose.
The duration of therapy depends on the clinical form of the disease and the patient's condition:
- The course of treatment for acute forms of the disease is at least 2 weeks;
- With prolonged intestinal dysfunction and post-dysentery colitis - at least 4-6 weeks;
- With chronic colitis, ulcerative colitis, enterocolitis - up to 45-60 days;
- During the period of convalescence after chemotherapy - 21-30 days.
If necessary, repeated courses of therapy or maintenance doses of Bifikol (half the age-specific daily dose) can be prescribed for 1-1.5 months.
Side effects
Side effects of the drug are not described.
Overdose
There is no information.
special instructions
You should not use Bifikol in the following cases:
- The drug has no labeling;
- The integrity of the packaging is broken;
- The physical properties of the lyophilisate are changed (it looks like a brown mass crumpled at the bottom of the bottle).
Drug interactions
Combined use with chemotherapy and antibiotic therapy is not recommended.
Analogs
Bifikol's analogues are Sporobacterin, Khilak forte, Bifidumbacterin dry, Bifilakt-BILS, Bifidumbacterin, Bactisporin, Colibacterin, Bactisubtil, Bifiliz, Bifinorm, Biosporin, Bifidumbacterin, Bifloriform-Simbiofifor, Probiofifor.
Terms and conditions of storage
Expiration date - 1 year.
Store at a temperature not exceeding 10 ° C, out of the reach of children.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Bificol
Patients leave mostly positive reviews about Bificol. Indicate that the drug has an immunostimulating effect, is effective in dysbiosis. The disadvantages include storage conditions and the difficulty of preparing a suspension.
The price of Bificol in pharmacies
The approximate price for Bifikol dry lyophilisate for the preparation of a suspension, per pack of 10 vials of 5 doses, is 207–250 rubles.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
