Bacteriophage salmonella groups A, B, C, D, E
Salmonella bacteriophage groups A, B, C, D, E: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Bacteriophagum Salmonellae gr. ABCDE
ATX code: V03A
Active ingredient: bacteriophage salmonella (Bacteriophagum Salmonellae)
Manufacturer: Microgen NPO, JSC (Russia)
Description and photo update: 2019-24-01
Salmonella bacteriophage is an immunostimulating agent with a specific antibacterial effect against Salmonella groups A, B, C, D and E.
Release form and composition
Dosage forms:
- solution for oral administration and topical use: transparent yellow liquid of varying intensity of staining (20 ml in vials, in a cardboard box 4 or 8 bottles; 100 ml in bottles, 1 bottle in a cardboard box);
- tablets with acid-resistant coating: round, biconvex, Ø - 7 mm, light gray or light beige color of varying intensity of staining, with light inclusions, marbling is allowed (50 pcs. in glass bottles, 10 bottles in a cardboard box).
Each pack also contains instructions for the use of Salmonella bacteriophage.
The composition of the solution in 1 bottle:
- active substance: bacteriophage salmonella groups A, B, C, D, E liquid - 20 or 100 ml;
- auxiliary component (preservative): quinosol.
Composition of 1 tablet:
- active substance: bacteriophage salmonella groups A, B, C, D, E - 72 mg;
- auxiliary components: calcium stearate, dextrose monohydrate, calcium gluconate monohydrate, skim milk (dry residue), purified talc, pectin.
Pharmacological properties
Pharmacodynamics
Salmonella bacteriophage of groups A, B, C, D, E is a microbiological agent that causes lysis of the following salmonella:
- group A - Salmonella paratyphi A;
- group B - Salmonella Heidelberg, Salmonella paratyphi B, Salmonella typhimurium;
- group C - Salmonella oranienburg, Salmonella choleraesuis, Salmonella infantis, Salmonella newport;
- group D - Salmonella enteritidis, Salmonella dublin;
- group E - Salmonella newlands, Salmonella analum.
Pharmacokinetics
No information available.
Indications for use
The salmonella bacteriophage is intended for the prevention and treatment of diseases and carriage of bacteria caused by salmonella groups A, B, C, D, E.
Contraindications
There are no restrictions on the use of a liquid bacteriophage in the form of a solution.
In the form of tablets, the drug is contraindicated in children under 1 year of age.
Salmonella bacteriophage, instructions for use: method and dosage
Oral and topical solution
Salmonella bacteriophage in the form of a solution is intended for oral and rectal (in the form of enemas after bowel cleansing) use. Shake the bottle thoroughly before use.
Inside, the drug is taken 1 hour before meals 3 times a day from the first day of detection of the disease. The course of treatment is 7-10 days.
In diseases accompanied by mild colitis syndrome, and during the recovery period, it is recommended to combine oral administration 2 times a day with 1 rectal administration.
Recommended single dosages for oral administration of Salmonella bacteriophage, depending on the patient's age:
- 0-6 months - 5 ml;
- 6-12 months - 10-15 ml;
- 1-3 years - 15-20 ml;
- 3–8 years old - 20–30 ml;
- from 8 years and older - 30-40 ml.
Recommended single dosages for rectal administration of Salmonella bacteriophage, depending on the patient's age:
- 0-6 months - 10 ml;
- 6-12 months - 20 ml;
- 1-3 years - 20-30 ml;
- 3–8 years old - 30–40 ml;
- 8 years and older - 50-60 ml.
For prophylactic purposes, bacteriophage is used to prevent the carriage of bacteria and the development of nosocomial infection, as well as to prevent infection during group diseases in families and organized groups. In this case, 1 age dose should be taken 1 time per day. The duration of the course is determined by the conditions of the epidemic situation.
Acid-resistant coated tablets
Salmonella bacteriophage in the form of tablets should be taken orally, 1 hour before meals 3 times a day, from the first day of the disease. The course of treatment is 7-10 days.
In diseases accompanied by a mild colitis syndrome, and during the recovery period, it is recommended to combine oral administration 2 times a day with 1 rectal application of a liquid bacteriophage in the form of enemas after bowel movement.
Recommended single dosages of Salmonella bacteriophage, depending on the patient's age:
- 1-3 years - 1 tablet;
- 3–8 years old - 1–2 tablets;
- from 8 years and older - 2-3 tablets.
For prophylactic purposes, the bacteriophage is taken at 1 age dose 1 time per day. The duration of the course is determined by the conditions of the epidemic situation.
Side effects
Until now, the development of side effects against the background of drug therapy has not been identified.
Overdose
There were no reports of cases of bacteriophage overdose.
special instructions
For effective phage therapy, it is important to preliminary determine the sensitivity of the pathogen to the drug and early start of treatment.
Do not use liquid bacteriophage if the solution becomes cloudy.
Influence on the ability to drive vehicles and complex mechanisms
No negative impact on mental and motor abilities of a person has been identified.
Application during pregnancy and lactation
Salmonella bacteriophage can be used during pregnancy and lactation according to appropriate indications and as directed by a doctor.
Pediatric use
The solution for oral administration and topical application has no age restrictions for use. In the form of tablets, the drug is contraindicated for the treatment of children under 1 year of age.
Drug interactions
The salmonella bacteriophage does not restrict the use of other drugs, including antibiotics.
Analogs
There is no information on analogues of Salmonella bacteriophage.
Terms and conditions of storage
Both dosage forms of the drug should be stored at a temperature of 2–8 ° C, protected from light, out of the reach of children, in a dry place.
The shelf life of the solution and tablets is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Salmonella bacteriophage
According to reviews, Salmonella bacteriophage is the only remedy that can cure diseases caused by Salmonella serotypes A, B, C, D, E. As many indicate, the greatest efficiency is observed when the oral and rectal methods of using the drug are combined. Additional advantages include the possibility of using the solution in children from birth, as well as good bacteriophage tolerance.
The disadvantage is the high cost, however, according to the majority, a complete cure after one course of therapy neutralizes this negative moment.
Price for Salmonella bacteriophage in pharmacies
Depending on the region of sale and the pharmacy network, the price for Salmonella bacteriophage for 1 bottle of 100 ml can be 586–845 rubles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
