Baclofen - Instructions, Application, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Baclofen

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Indications for use
4. 4. Instructions for use
5. 5. Side effects from use
6. 6. Contraindications to use

Baclofen is a drug that has a powerful effect on the neuromuscular transmission of impulses. Has a strong antidepressant effect.

Pharmacological action of Baclofen

The use of Baclofen leads to the following actions on the body:

• Muscle relaxant;
• Antispastic;
• Analgesic.

According to the instructions for Baclofen, the drug has a depressing effect on monosynaptic and polysynaptic reflexes of the spinal cord, and also significantly reduces muscle tone.

According to patients' reviews, Baclofen is well absorbed from the gastrointestinal tract. The maximum effect after taking the drug reaches after 2 - 3 hours. The drug is excreted from the body through the kidneys.

Release form

According to the instructions for Baclofen, the drug is available in tablets of 10 mg and 25 mg.

Accordingly, 1 tablet contains 10 and 25 mg of the active ingredient (directly baclofen). The tablets are packed in bottles of 50 pieces, the bottles are placed in cardboard boxes.

Indications for use

The main indications for instructions for Baclofen are the following health disorders:

• Multiple sclerosis;
• Cerebral paralysis;
• Other paralytic syndromes;
• Other brain lesions;
• Other spinal cord diseases;
• Stroke not specified as hemorrhage or heart attack;
• Cramp and spasm;
• Head trauma;
• Spinal cord injuries at an unspecified level (tumors).

Instructions for the use of Baclofen

According to the instructions, Baclofen is taken with meals. The initial dose of the drug for both adults and children is 5 mg 3 times a day. One dose is 1/2 tablet of Baclofen with a dosage of 10 mg. The dose of the drug is increased every 3 days. This happens gradually to prevent overdose. Under the supervision of a physician, with strict adherence to the instructions for Baclofen, the dose is increased until the desired therapeutic effect is obtained. As a rule, for an adult, the maximum dose of Baclofen reaches a level of 30 to 75 mg per day.

In the case of prescribing and using Baclofen in high doses, the drug should be used at a dosage of 25 mg. Nevertheless, as evidenced by the instructions for Baclofen, the maximum dose of the drug per day should not exceed 100 mg.

For children from 1 to 2 years old, according to the instructions for Baclofen, usually no more than 20 mg per day is prescribed. The daily dose of the drug for children 2 years old - 6 years old is from 20 to 30 mg. From 6 to 10 years old, the use of Baclofen is permissible in the amount of 30 - 60 mg. And after 10 years, another scheme for using Baclofen is used according to the instructions: based on the weight of the child. So, at this age, children can use Baclofen at the rate of 1.5 - 2 mg per 1 kilogram of weight.

Reviews for Baclofen have information that the drug should be used with caution for the following diseases and health disorders:

• Dysfunction of the kidneys and liver;
• Cerebral stroke;
• Respiratory system disorders;
• Increased tone of the sphincter in the bladder;
• Psychotic syndrome;
• Schizophrenia;
• Convulsive state;
• Confused state of mind.

Numerous reviews of Baclofen contain information about the negative consequences of taking the drug in older people. Therefore, persons over 65 years of age need to be very careful when using Baclofen.

After the treatment, according to the instructions for Baclofen, it is necessary to slowly reduce the dose of the drug. From the reviews about Baclofen it is known that a sharp decrease in dosage can lead to the following problems:

• Convulsions;
• Restless state;
• Anxiety;
• Hallucinations;
• Mental disorders;
• Increased muscle tone.

The use of Baclofen can negatively affect concentration, therefore it is not advised to drive a car during this period. It is best to take a vacation for the duration of treatment, or to carry out treatment in a hospital.

Side effects from the use of Baclofen

Due to the fact that the drug has a powerful effect, the occurrence of side effects from the use of Baclofen is quite possible. This danger increases due to non-compliance with the instructions for Baclofen.

So, the side effects of using Baclofen can be different. For example, on the part of the senses and the nervous system, reviews of Baclofen contain the following information about side effects:

• Drowsiness or, conversely, insomnia;
• Dizziness;
• Headache;
• Fatigue;
• Weakness;
• Confusion in consciousness;
• Imbalance and coordination of movements;
• Decreased reactivity;
• Mental arousal;
• A state of euphoria;
• Hallucinations;
• Depression;
• Nightmares.

In reviews of Baclofen, there is evidence of a serious reaction of the body to the action of the drug on the part of the cardiovascular system. Such a reaction appears in the form of the following violations:

• Arterial hypertension;
• Heart palpitations (tachycardia);
• Chest pain;
• Cardiac collapse.

The gastrointestinal tract also actively responds to the use of Baclofen, if the dosage is violated. The body's response in this case is the following reactions:

• Loss of appetite (aversion to food);
• Changing tastes;
• Nausea;
• Constipation or diarrhea;
• Vomiting;
• Dyspepsia;
• Abdominal pain.

In case of violation of the instructions for Baclofen and the use of the drug without a medical prescription, negative reactions from the genitourinary system of the body are possible:

• Enuresis (urinary incontinence);
• Spontaneous urination and defecation;
• Ejaculation disorder;
• Impotence.

The human respiratory system, according to reviews of Baclofen obtained from patients, reacts to a violation of the dosage according to the instructions for Baclofen, difficulty breathing (nasal congestion) and even a state of suffocation.

Other manifestations of side effects from the use of Baclofen can be such signs as:

• Muscle pain;
• Rash on the skin;
• Itching;
• Swelling of the limbs;
• Increased sweating;
• Weight gain (extra pounds).

If the use of Baclofen is accompanied by signs such as chest pain, skin rash, depression, vomiting, difficulty breathing, you should immediately consult a doctor or call an ambulance.

In case of violation of the instructions for Baclofen and the assumption of an overdose of the drug, the following emergency measures are applied:

1. Gastric lavage

2. Taking activated carbon or other absorbent

3. Artificial respiration (in case of respiratory arrest)

4. Urgent maintenance of the cardiovascular system

Contraindications to the use of Baclofen

Contraindications to the use of Baclofen are the following situations:

• Hypersensitivity to the active substance of the drug;
• Peptic ulcer of the stomach and (or) duodenal ulcer.

According to reviews for Baclofen, it is prescribed during pregnancy only in exceptional cases when the therapeutic effect of Baclofen is higher than the potential risk to the fetus. Breastfeeding and the use of Baclofen are incompatible.

Especially careful should be the use of Baclofen according to the instructions in cases of liver and kidney disease.

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!