Afobazole Overdose - Signs, First Aid, Treatment, Consequences

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Overdose with Afobazole

The modern rhythm of life makes increased demands on the human body, this often becomes the cause of chronic stress, and even the development of a depressive state. Sometimes it is impossible to cope with this without the help of pharmacological agents. One of the drugs that help in this is Afobazol. It has a pronounced sedative effect and generally low toxicity, but its abuse often leads to the development of an overdose.

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How much Afobazole is needed for an overdose?

At the initial stage of treatment, it is usually recommended to take Afobazol 10 mg (1 tab.) No more than 3 times a day. If necessary, the daily dose can be increased to 60 mg. The duration of the course is determined individually.

For the development of an overdose with Afobazole, it is necessary to take a dose that exceeds the therapeutic one by 40-60 times. In this case, the drug has a pronounced inhibitory effect on the central nervous system, up to the development of paralysis of the respiratory center.

An overdose when taking therapeutic doses is also not excluded, it occurs in the case of joint administration of Afobazole with tranquilizers (Diazepam, Seduxen, Valium) or alcohol. This is due to the fact that ethyl alcohol and tranquilizers potentiate the inhibitory effect of Afobazole on the central nervous system, and besides, they themselves act in a similar way.

Signs of overdose

An overdose with Afobazole is characterized by:

• drowsiness;
• general weakness (muscle tone remains preserved);
• lethargy;
• blurred speech;
• shallow breathing;
• fainting conditions.

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First aid for overdose with Afobazole

In case of overdose, it is necessary:

1. Flush the stomach. At home, washing is performed without a probe: drink a few glasses of cool water (you should not use warm water, since this will increase the rate of absorption of the drug into the bloodstream), then induce vomiting by irritating the root of the tongue. The procedure is performed several times in a row. Gastric lavage is effective only if no more than 3 hours have passed since the moment of taking the medicine, if more, they immediately go to the next point.
2. Take a sorbent to prevent absorption into the bloodstream of the drug that has managed to penetrate into the small intestine. For this purpose, Polysorb, Activated Carbon, Smecta, Filtrum STI or any other drug with sorbing properties are suitable.
3. Drink black coffee. Caffeine stimulates the central nervous system, helps to reduce drowsiness and weakness, activates the respiratory center, thereby weakening the effect of Afobazol.
4. Drink a lot. Tea, plain or still mineral water will do. Drinking plenty of fluids will reduce the concentration of Afobazole in the blood, and will also increase urine output, which will allow you to quickly remove the drug from the body.

Antidote

There is no specific antidote to Afobazol.

When is medical attention needed?

In case of an overdose with Afobazole, it is imperative to seek medical help even if the victim or others think that his condition does not inspire concern, since after a period of well-being, a sharp deterioration can occur at any time.

Treatment is carried out in the toxicology department. To accelerate the elimination of the drug, forced diuresis is shown: intravenous infusion of saline solutions and glucose solution is performed with parallel administration of diuretics.

With severe weakness and respiratory failure, caffeine is injected subcutaneously.

Possible consequences

An overdose of Afobazole responds well to therapy and passes without any long-term negative consequences. No fatalities have been reported.

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Elena Minkina Doctor anesthesiologist-resuscitator About the author

Education: graduated from the Tashkent State Medical Institute, specializing in general medicine in 1991. Repeatedly passed refresher courses.

Work experience: anesthesiologist-resuscitator of the city maternity complex, resuscitator of the hemodialysis department.

The information is generalized and provided for informational purposes only. At the first sign of illness, see your doctor. Self-medication is hazardous to health!