Doxycycline
Instructions for use:
- 1. Pharmacological action
- 2. Indications for use
- 3. Instructions for use
- 4. Side effects
- 5. Contraindications to use
- 6. Additional information
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from 269 rub.
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Doxycycline is an antimicrobial drug of the tetracyclines group.
pharmachologic effect
Doxycycline is a broad-spectrum antibiotic, active against many bacteria (streptococcus, staphylococcus, salmonella, dysentery bacillus, causative agents of syphilis and gonorrhea), rickettsia (causative agents of typhoid fever), mycoplasma (causes diseases of the genitourinary system), chlamydia (cause infectious diseases) sexually transmitted infections).
Sensitive to the action of the drug Doxycycline ureaplasma, which is an intracellular parasite that affects the genitals and urinary tract. Doxycycline does not work on fungal infections and viruses. Penetrating into the cell of a microorganism, Doxycycline disrupts protein synthesis in it, which leads to the fact that the bacterium loses its ability to reproduce and soon dies on its own.
The maximum concentration of Doxycycline in the blood can be observed 2 hours after taking the drug in the form of capsules. After a single use of Doxycycline, the therapeutic concentration in the blood remains for 18-24 hours, which allows you to take this antibiotic once a day. Doxycycline, reviews confirm, in comparison with its progenitor, tetracycline, has a wider spectrum of action and fewer possible side effects.
Indications for the use of Doxycycline
The instruction recommends to use Doxycycline when:
- respiratory tract infections: pleurisy, pleural empyema, bronchitis, pneumonia;
- ENT infections: otitis media, sinusitis, tonsillitis, tonsillitis;
- infections of the digestive tract: periodontitis, proctitis, peritonitis, cholangitis, cholecystitis;
- urinary tract infections: urethritis, pyelonephritis;
- diseases in women of the pelvic organs of an inflammatory nature;
- acute and chronic prostatitis, epididymitis;
- purulent infections of soft tissues, acne;
- infectious ulcerative keratitis;
- prevention of infections after colon surgery, medical abortion;
- prevention of malaria during short-term travel to countries where this disease is widespread;
- mycoplasma, chlamydia, syphilis, gonorrhea;
- whooping cough, brucellosis, rickettsiosis;
- osteomyelitis, Q fever, Rocky Mountain spotted fever, typhus;
- yersiniosis, bacillary and amoebic dysentery, borreliosis, tularemia, cholera;
- Lyme disease, leptospirosis, actinomycosis;
- trachoma, psittacosis, granulocytic erpiichiosis;
- infections caused by Haemophilus influenzae.
Reviews of Doxycycline confirm the effectiveness of the drug for the above diseases.
Instructions for the use of Doxycycline
Doxycycline is available in capsule form for oral administration and as a solution for injection.
It is recommended to use Doxycycline in the form of capsules after meals with water to prevent possible irritation of the esophagus. The daily dose is taken either once every 24 hours, or twice with an interval of 12 hours.
Most infections involve taking 200 mg of Doxycycline on the first day of treatment and 100-200 mg on the following days. Infections provoked by chlamydia, mycoplasma, ureaplasma, Doxycycline cures in 10-14 days.
More severe forms of infections involve taking 200 mg of Doxycycline throughout the course of treatment. In women, pelvic inflammatory disease is recommended to be treated by taking 100 mg of the drug 2 times a day, in men - 2 times a day 100 mg or 300 mg once. In a medical abortion, 100 mg of Doxycycline is used 1 hour before the operation, and after its completion half an hour later, another 200 mg.
In syphilis, the instruction recommends using Doxycycline for 10 days, 300 mg every day. Within 2-4 days, 100 mg 2 times a day take Doxycycline for gonorrhea. A single dose of 300 mg treats gonorrheal urethritis in men, however, if the expected effect has not been obtained, men continue to take Doxycycline for 4 days at 200 mg, and women - one day longer.
For acne, the use of Doxycycline is effective in a daily dose corresponding to 50 mg for 6-12 weeks.
According to the instructions, Doxycycline can be taken by children over 8 years old: 4 mg / kg on the first day of treatment, 2-4 mg / kg on the following days.
Solution for injection is injected intravenously every 12 hours. Before use, 100 mg of Doxycycline (1 ampoule) should be diluted with 10 ml of water for injection, after which 1 l of physiological solution is added to the resulting solution.
Side effects
To the undesirable effects of the drug Doxycycline, reviews and clinical studies include:
- nausea, vomiting, abdominal pain, anorexia;
- skin rash, swelling, itching;
- sweating, dizziness;
- rarely - eosinophilia (an increase in the number of eosinophils in the blood), photosensitization (increased sensitivity to light), Quincke's edema (an increase in part or all of the face, limbs).
- with long-term use - thrombocytopenia (reduced platelet count), neutropenia (decreased neutrophil count), hemolytic anemia (sustained destruction of red blood cells), development of intestinal dysbiosis, thrush, persistent tooth discoloration.
Contraindications to the use of Doxycycline
According to the instructions, Doxycycline is contraindicated in porphyria (an increased number of porphyrins in the blood), leukopenia (a decrease in the number of leukocytes), severe hepatic failure, hypersensitivity to tetracycline or doxycycline.
Doxycycline is not prescribed during lactation, during pregnancy and children under 8 years of age. If a pregnant woman has been diagnosed with ureaplasma, mycoplasma or other infectious diseases that are sensitive to the drug Doxycycline, the doctor should weigh the possible harm and potential benefits of the drug or choose another antibiotic.
Additional Information
To store Doxycycline, you need a dry and dark place with an air temperature of up to 25 0 C. The shelf life of this antibacterial drug is 4 years.
Doxycycline: prices in online pharmacies
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Drug name Price Pharmacy |
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Doxycycline solution tablets dispersible tablets 100mg 10pcs 269 r Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
