Artichoke extract
Artichoke extract: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Extract of Artichokes
ATX code: A05AX
Active ingredient: Artichoke leaves extract (Cynarae scomuli foliae extract)
Manufacturer: Evalar, CJSC (Russia), Zdorovye, LLC (Ukraine)
Description and photo updated: 2019-27-08
Prices in pharmacies: from 80 rubles.
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Artichoke extract is a preparation / biologically active food supplement of plant origin with hepatoprotective, choleretic, diuretic action.
Release form and composition
Dosage forms of release:
- tablets - biologically active food additive - 550 or 590 mg each (20 or 60 pcs. in a package);
- capsules: hard gelatinous, with a body and a lid from orange-brown to brown; the capsules contain a finely granular powder from dark to light brown with a gray tint (10 pieces in blisters, 3 or 6 blisters in a cardboard box);
- oral solution: from dark brown to brown, has a specific odor; during storage, the formation of a greenish tint, opalescence and precipitation are permissible (in glass or polymer bottles of 100 ml, 1 bottle in a cardboard box, complete with a dosing device).
Each pack also contains instructions for the use of Artichoke extract.
Composition of 1 tablet:
- active substance: artichoke extract - 300 mg (including hydroxycinnamic acids - 12 mg);
- auxiliary components: microcrystalline cellulose and lactose (fillers), croscarmellose sodium, colloidal silicon dioxide, stearic acid and vegetable calcium stearate (anti-caking additives).
Composition of 1 capsule:
- active substance: dry artichoke extract - 100 or 300 mg (in the form of a thick artichoke extract (7.5: 1) from fresh grass);
- auxiliary components: calcium stearate, microcrystalline cellulose, anhydrous colloidal silicon dioxide, polysorbate 80.
Composition of 1 ml solution for oral administration:
- active substance: dry artichoke extract - 100 mg (in the form of a thick artichoke extract (7.5: 1); extractant - purified water);
- auxiliary components: sodium saccharin, glycerin, 96% ethanol, methylparaben (E 218), sorbitol (E 420), propylparaben (E 216), purified water.
Pharmacological properties
Pharmacodynamics
Artichoke extract is a herbal medicine. It has a diuretic, choleretic, hypolipidemic and hepatoprotective effect.
Against the background of its use, bile secretion increases, the secretion of nitrogen-containing substances (creatinine, urea), toxins from the body improves, and the content of total cholesterol in the blood decreases.
Such biologically active substances as vitamins B 1 and B 2, carotene, ascorbic acid, insulin, contribute to the normalization of metabolic processes.
Indications for use
Pills
Artichoke extract tablets as a food supplement are prescribed as a source of hydroxycinnamic acids to improve the functional state of the liver, the secretion and outflow of bile, digestion (especially when consuming a significant amount of fatty foods and carbohydrates), cholesterol metabolism, as well as to support biochemical processes in liver cells …
Capsules, oral solution
- non-calculous cholecystitis in a chronic course;
- dyskinesia of the biliary tract of the hypotonic-hypokinetic type;
- hepatitis of various origins in the chronic course;
- dyspepsia (heaviness in the epigastrium, nausea, flatulence, belching);
- renal failure in a chronic course;
- intoxication (with heavy metal salts, nitro compounds, hepatotoxic substances, alkaloids) in a chronic course.
Contraindications
Pills
- pregnancy and lactation;
- hypersensitivity to the components of the dietary supplement.
Capsules, oral solution
- gallstone disease, obstruction of the biliary tract;
- liver failure, acute hepatitis;
- suppuration (empyema) of the gallbladder (for oral solution);
- acute kidney disease (for oral solution);
- age up to 6 children (capsules of 100 mg, solution for oral administration) or up to 12 children (capsules of 300 mg);
- lactation period;
- hypersensitivity to the components of the drug, as well as to other plants of the Asteraceae family.
For pregnant women, the appointment of Artichoke extract is possible only after an individual assessment of the benefit / risk ratio.
Artichoke extract, instructions for use: method and dosage
Pills
The Artichoke extract tablet is taken orally, preferably during a meal.
Single dose - 2 tablets, frequency of administration - 2 times a day.
Duration of admission is up to 30 days. After 10 days, the doctor may prescribe a second course.
Capsules, oral solution
The solution and capsules are taken orally, preferably before meals for 15-30 minutes.
The doctor sets the dosage regimen individually (determined by the severity of the condition).
The recommended single dose (with a frequency of taking 3 times a day):
- 100 mg capsules: children 6-12 years old - 1 capsule, adults and children from 12 years old - 2-3 capsules;
- 300 mg capsules: adults and children from 12 years old - 1 capsule;
- solution for oral administration: children 6-12 years old - 1 ml, adults and children from 12 years old - 2-3 ml; shake the bottle with the solution before taking; a single dose is diluted in a small volume of water (30 ml - about 2 tablespoons).
The duration of the drug intake is from 2 to 4 weeks. After 1-2 months, the doctor may prescribe a second course.
Side effects
Pills
There is no information on the development of adverse reactions.
Capsules, oral solution
Long-term use of high doses of Artichoke extract can lead to the development of diarrhea, pain in the upper abdomen, heartburn, nausea, and allergic reactions.
Overdose
The main symptom of an overdose is diarrhea.
Therapy: gastric lavage, symptomatic treatment.
special instructions
Pills
Before using Artichoke extract, as well as in cases of development of uncharacteristic symptoms, you should consult a doctor.
Capsules, oral solution
With prolonged use of Artichoke extract, the level of cholesterol and nitrogen-containing substances in the blood decreases.
Application during pregnancy and lactation
- tablets (dietary supplements): not prescribed during pregnancy / lactation;
- capsules, solution for oral administration: pregnancy - the appointment of the drug is possible only after an individual assessment of the balance of benefits and risks; lactation period - therapy is contraindicated.
Pediatric use
Children under the age of 6 are contraindicated in taking capsules weighing 100 mg and a solution for oral administration. Capsules weighing 300 mg are not prescribed for the treatment of children under 12 years of age.
Tablets (dietary supplements) are not used in pediatrics.
With impaired renal function
In the acute course of kidney disease, oral solution is contraindicated.
For violations of liver function
With liver failure, acute hepatitis, the use of Artichoke extract is contraindicated.
Drug interactions
With the combined use of capsules and oral solution of Artichoke extract with certain drugs / substances, the following effects may develop:
- coumarin anticoagulants (phenprocoumon, warfarin): weakening of their action (correction of their dose may be required);
- hypoazotemic and hypocholesterolemic drugs: enhancement of their action.
Analogs
The analogues of the Artichoke extract are: Holebil, Hofitol, Holosas, Holos, Holemax, etc.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Shelf life:
- tablets - 3 years;
- capsules, oral solution - 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Artichoke extract
Reviews of Artichoke extract are mostly positive. The high efficiency of the drug and its plant composition are noted. In some cases, a long course of use is required to achieve a therapeutic effect.
Price for Artichoke extract in pharmacies
Approximate price for Artichoke extract 590 mg tablet for 20 pcs. in the package is 132-140 rubles.
Artichoke extract: prices in online pharmacies
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Drug name Price Pharmacy |
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Artichoke extract 590 mg tablets 20 pcs. RUB 80 Buy |
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Evalar Artichoke extract for liver tablets 500 mg 20 pcs. 132 RUB Buy |
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Artichoke extract tablets 60 pcs. 308 RUB Buy |
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NOW Artichoke extract 450 mg capsule 90 pcs 1514 RUB Buy |
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NOW (NAU Foods) Artichoke extract capsule 565 mg 90 pcs. 1740 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
