Anhidak
Anidak: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Angidak
ATX code: A01AD02
Active ingredient: benzydamine (benzydamine)
Manufacturer: Grotex, LLC (Russia)
Description and photo update: 2018-27-11
Prices in pharmacies: from 185 rubles.
Buy
Anidak is a local drug with anti-inflammatory, analgesic, antiseptic action, used in the treatment of inflammatory diseases of the ENT organs and oral cavity of various etiologies.
Release form and composition
Dosage form - spray for topical use, dosed: transparent, colorless or somewhat yellowish, has a characteristic mint smell [in high density polyethylene bottles, in a cardboard box 1 bottle of 15 ml (88 doses) or 30 ml (176 doses) and instructions for application of Anidaka].
Composition of 1 spray dose:
- active substance: benzydamine hydrochloride - 0.255 mg;
- auxiliary components: polysorbate 20 - 0.009 mg, 0.5 M hydrochloric acid solution or 1 M sodium hydroxide solution - up to pH 5-7, menthol flavor - 0.051 mg, glycerin - 8.52 mg, 95% ethanol - 13.89 mg, methyl parahydroxybenzoate - 0.17 mg, sodium saccharinate - 0.041 mg, sodium bicarbonate - 0.019 mg, water for injection - up to 0.17 ml.
Pharmacological properties
Pharmacodynamics
Benzydamine, the active ingredient of Anidaca, is a non-steroidal anti-inflammatory drug (NSAID) belonging to the indazole group. It has a local anesthetic and anti-inflammatory effect, restores microcirculation, and has antiseptic activity against a wide range of microorganisms. The mechanism of action of benzydamine is based on the stabilization of cell membranes and inhibition of prostaglandin synthesis.
The substance has antibacterial and specific antimicrobial properties, which is manifested by the rapid penetration of microorganisms through the membranes, resulting in damage to cellular structures, disruption of metabolic processes and cell death.
Benzydamine is active against Candida albicans. It leads to structural modifications of the cell walls of fungi and their metabolic chains, which becomes an obstacle to their reproduction and is the basis for the use of benzydamine against the background of inflammation in the oral cavity, including processes of an infectious origin.
Pharmacokinetics
When applied topically through the mucous membranes, benzydamine is well absorbed and penetrates into inflamed tissues. In blood plasma, it is found in an amount that is not enough to obtain systemic effects.
Excretion of the substance occurs mainly by the kidneys in the form of conjugation products or inactive metabolites.
Indications for use
Anidak is prescribed for the symptomatic treatment of pain syndrome of inflammatory diseases of the ENT organs and the oral cavity of various origins:
- candidiasis of the oral mucosa (in combination with other drugs);
- periodontal disease, glossitis, gingivitis, stomatitis (including after radiation and chemotherapy);
- conditions after surgical interventions (tonsillectomy), injuries (fractures of the jaw), treatment / extraction of teeth;
- calculous inflammation of the salivary glands;
- laryngitis, pharyngitis, tonsillitis.
For patients with inflammatory and infectious diseases, for whom systemic treatment is indicated, Anidak is prescribed in combination with other drugs.
Contraindications
Absolute:
- age up to 3 years;
- pregnancy and the period of breastfeeding;
- individual intolerance to the components of the drug.
Relative (Anidak spray is prescribed under medical supervision):
- bronchial asthma (currently or in history);
- hypersensitivity to acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs.
Anidak, instructions for use: method and dosage
Spray Anhidak is applied topically after meals. One injection (one dose) corresponds to 0.255 mg benzydamine.
Recommended single dose:
- children 3–6 years old: 1 injection for every 4 kg of body weight, the maximum single dose is 4 injections;
- children 6–12 years old: 4 injections;
- children from 12 years old and adults (including elderly patients): 4-8 injections.
The drug is used from 2 to 6 times a day for a course of 7 days. If there is no improvement during this period, you need to consult your doctor.
Mode of application:
- Turn the white tube (cannula) to the "vertical to the bottle" position.
- Insert the cannula into the mouth and direct to the sore throat and mouth.
- Press the dosing pump on the top of the bottle, one press - one dose. During the injection, you need to hold your breath.
Side effects
During the period of therapy with Anidak, the following disorders may occur (> 10% - very often;> 1% and 0.1% and 0.01% and <0.1% - rarely; <0.01% - very rarely; with an unknown frequency - based on the available data, it is not possible to determine the frequency of occurrence of adverse reactions):
- allergic reactions: infrequently - photosensitivity; rarely - itching / rash, hypersensitivity reactions; very rarely - laryngospasm, angioedema; with an unknown frequency - anaphylactic reactions;
- local reactions: rarely - burning sensation in the mouth, dry mouth; with an unspecified frequency - a feeling of numbness in the oral cavity.
Overdose
When using Anidaka in accordance with the instructions, an overdose is unlikely. No cases of overdose have been reported.
The main symptoms (with accidental swallowing of Anidak): respiratory depression, abdominal cramps, vomiting, ataxia, anxiety, hallucinations, fear, convulsions, tachycardia, fever.
Therapy: symptomatic; the stomach should be emptied by inducing vomiting, or the stomach should be flushed using a gastric tube. The patient's condition should be monitored by medical supervision, supportive therapy and the necessary hydration provided. No antidote known.
special instructions
In case of development of hypersensitivity reactions, the abolition of Anidak is recommended. To prescribe the appropriate therapy, you must consult a doctor.
In some patients, ulcers in the mouth and throat indicate serious pathologies. If symptoms persist for 3 days or more, you should consult a specialist.
Anidaka contains parahydroxybenzoates, which can cause allergic reactions.
One dose (one injection) of the drug contains 13.2 mg of ethanol.
Application during pregnancy and lactation
The use of Anhidaka during pregnancy / lactation is not recommended.
Pediatric use
For patients under 3 years of age, the drug is not prescribed.
Drug interactions
There is no information.
Analogs
Analogues of Anidak are: Asterisk ENT, Tantum Verde, Tantum Rose, Bronflex, Oralsept, Benzidamine.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Anhidak
Reviews about Anhidaka are mostly positive. Patients indicate that the drug effectively relieves sore throat of various etiologies. The cost is assessed as affordable.
Price for Anhidak in pharmacies
The approximate price for Anhidak is 156-175 rubles. (1 bottle of 15 ml) or 203-270 rubles. (1 bottle of 30 ml).
Anhidak: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Anidak spray for topical application 88 doses 15 ml 1 pc. RUB 185 Buy |
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Anidak spray for topical application 176 doses 30 ml 1 pc. 242 r Buy |
|
Anidak spray for local approx. dosage. 0.255 mg / dose vial 30ml (176 doses) 280 RUB Buy |
|
Anidak sept rr d / places. approx. 0.15% fl. 150ml No. 1 292 r Buy |
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Anhidak forte spray for places. approx. dosage. 0.51mg / dose vial 30ml RUB 315 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
