Endonorm
Endonorm: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Endonorm
Active ingredient: white cinquefoil extract (potentilla alba)
Producer: MiraxBioFarma CJSC (Russia)
Description and photo updated: 2018-23-11
Prices in pharmacies: from 1419 rubles.
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Endonorm is a biologically active additive (BAA), a gonadotropic and thyroid-stimulating agent of plant origin.
Release form and composition
Dosage form - capsules of 400 mg: hard gelatin (60 and 90 pcs. In polymer cans, 1 can in a cardboard box).
Active ingredients in one capsule:
- dry extract of licorice roots - 50 mg;
- powder of sugary kelp thallus - 70 mg;
- dry extract of the herb of the three-part series - 80 mg;
- dry extract of the roots and rhizomes of white cinquefoil - 200 mg.
Pharmacological properties
Endonorm has a wide range of pharmacological effects, which is due to the total action of the following biologically active substances included in its composition: glycyrrhizic acids of licorice, albinin, phenylpropanoids and iridoids of the tripartite series, the sum of phenolic compounds and triterpene glycosides of Potentilla white.
In the prevention of thyroid diseases and the treatment of metabolic syndrome, Endonorm restores the function of the thyroid gland, increases the intensity of metabolic processes in the tissues of the body.
The therapeutic effect in autoimmune thyroiditis, euthyroid (diffuse, nodular, multinodular) and endemic goiter is due to the mediated effect of the drug, is achieved by reducing the functional overload of the thyroid gland and changing the reactivity of its humoral regulation.
In hypothyroidism, the drug increases the functional activity of the thyroid gland, which is determined by its ability to activate proliferative processes in the interfollicular islets and increase the rate of synthetic processes.
In hyperthyroidism and thyrotoxicosis Endonorm inhibits the secretion of thyroid hormones by thyrocytes and inhibits the peripheral conversion of T4 / T3, thereby reducing the functional activity of the thyroid gland.
In cases of hyperplastic diseases of the female reproductive system, Endonorm has a pronounced anti-inflammatory and gonadotropic effect.
In the climacteric period, the drug normalizes the level of gonadotropic hormones (due to an indirect effect on the hypothalamic-pituitary system) and increases the functional activity of the adrenal cortex.
Indications for use
- metabolic syndrome (complex treatment);
- hypothyroidism;
- hyperthyroidism;
- thyrotoxicosis;
- autoimmune thyroiditis;
- endemic, euthyroid (diffuse, nodular, multinodular) goiter;
- hyperplastic diseases of the female reproductive system, such as mastopathy, endometriosis and endometrial hyperplasia (complex treatment);
- climacteric syndrome.
Contraindications
According to the instructions, Endonorm is contraindicated in acute inflammatory diseases of the digestive system and individual intolerance to the components of the drug.
Due to the lack of clinical data, it is not recommended to prescribe the drug to children under 12 years of age, pregnant and lactating women.
Instructions for use of Endonorm: method and dosage
Endonorm should be taken orally 10 minutes before meals.
Recommended dosage:
- hypothyroidism, autoimmune thyroiditis, nodular goiter: adults - 1 capsule 3 times a day, children from 12 years old - 1 capsule 2 times a day. The duration of treatment is at least 2 months. If it is necessary to carry out repeated courses, the intervals between them should be observed in 7 days;
- prevention of thyroid diseases: adults - 1 capsule 2 times a day, children from 12 years old - 1 capsule a day. The duration of treatment is 1 month. The interval between courses is 6 months;
- complex treatment of hyperplastic diseases of the female reproductive system, climacteric syndrome, complex treatment of metabolic syndrome: adults - 1 capsule 3 times a day, children from 12 years old - 1 capsule 2 times a day. The duration of treatment is 3 months. The interval between courses is 7 days;
- hyperthyroidism (hyperfunction, Graves disease, thyrotoxicosis, diffuse toxic goiter): adults from the 1st to the 20th day are prescribed 2 capsules 3 times a day, then - 1 capsule 3 times a day, children from 1 to 20 On the 1st day, 2 capsules are prescribed 2 times a day, then - 1 capsule 2 times a day. The duration of treatment is 3 months. The interval between courses is 5 days.
Side effects
Endonorm can cause dyspeptic reactions (indigestion).
Overdose
Overdose cases have not been reported to date.
special instructions
In order to achieve the maximum therapeutic effect, it is recommended to accompany the reception of Endonorm with a special diet.
You should completely exclude or at least limit the use of products containing strumogenic (goitrogenic) substances, since they disrupt the functioning of the thyroid gland. Strumogens include not only food products, but also chemical and pharmaceutical products:
- foods rich in thiocyanates: soybeans, turnips, rapeseed, turnips, millet, broccoli, cauliflower, Brussels sprouts and cabbage;
- medicines: parathyroid hormone, insulin, carbamazepine, phenobarbital, fluoxetine, phenytoin, estrogenic contraceptives, etc.;
- heavy metals (radiation) and halogens: bromine, chlorine, fluorine, etc.;
- herbicides and pesticides.
Long-term use of these products in large quantities and long-term use of the corresponding drugs can cause disruption of the thyroid gland and the formation of goiter.
It is recommended to include in the diet foods rich in vitamin C, zinc and selenium:
- foods rich in vitamin C: sweet red pepper (bulgarian), black currant, rose hips, sea buckthorn, fresh juices;
- foods rich in zinc: chicken eggs, legumes (peanuts, peas, beans, lentils, etc.), oatmeal, pumpkin seeds, liver, heart, red meat;
- Selenium-rich foods: garlic, brewer's yeast, pistachios, coconut, shrimp, sea fish (herring, cod, hake, etc.), crabs.
It is also possible to receive ready-made vitamin and mineral complexes.
Application during pregnancy and lactation
During lactation and during breastfeeding, Endonorm is not prescribed due to the lack of sufficient clinical data on the safety of its use.
Pediatric use
The drug is contraindicated for use in patients under 12 years of age.
Drug interactions
Due to a possible change in the pharmacological effect, Endonorm can be used simultaneously with thyreostatics and thyroid hormones only as directed by the attending physician and under his control.
Only the attending physician can cancel the prescribed treatment.
Analogs
The analogues of Endonorm are Iodine-Active, Thyroid Compositum, Endocrinol, Merkazolin, Eutirox.
Terms and conditions of storage
Store in tightly closed original packaging in a dry place, protected from light and out of reach of children, at temperatures up to 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Endonorm
Reviews about Endonorm are mostly positive. Patients confirm its effectiveness, note the absence of side effects, especially note the natural herbal composition of the drug.
Price for Endonorm in pharmacies
Approximate prices for Endonorm: 1485-2350 rubles. per pack of 60 capsules, 1940–2960 rubles. per pack of 90 capsules.
Endonorm: prices in online pharmacies
|
Drug name Price Pharmacy |
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Endonorm 400 mg capsules 60 pcs. 1419 RUB Buy |
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Endonorm 400 mg capsules 90 pcs. 1769 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
