Pilobact

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Instructions for use:

1. Release form and composition
2. Indications for use
3. Contraindications
4. Method of application and dosage
5. Side effects
6. Special instructions
7. Drug interactions
8. Analogs
9. Terms and conditions of storage
10. Terms of dispensing from pharmacies

Prices in online pharmacies:

from 737 rub.

Buy

Pilobact is an antiulcer drug that has a bactericidal effect on Helicobacter pylori (a spiral-shaped gram-negative bacterium that lives exclusively in the human stomach).

Release form and composition

Pilobact is produced in the form of a combined set of tablets and capsules (2 capsules of omeprazole, 2 tablets of clarithromycin and 2 tablets of tinidazole (total of 6 pcs.) In blisters, 7 blisters in a cardboard box).

The active ingredient is a part of 1 capsule of omeprazole: omeprazole - 20 mg.

The composition of 1 tablet, coated, clarithromycin contains the active substance: clarithromycin - 250 mg.

The composition of 1 film-coated tablet of tinidazole contains the active substance: tinidazole - 500 mg.

Indications for use

Pilobact is prescribed for eradication therapy of Helicobacter pylori (Helicobacter pylori) in case of duodenal ulcer.

Contraindications

Porphyria;
Oppression of bone marrow hematopoiesis;
Hepatic / renal impairment;
Organic diseases of the central nervous system;
Simultaneous use with ethanol, terfenadine, cisapride, astemizole, pimozide;
Pregnancy and lactation;
Age under 18;
Hypersensitivity to omeprazole, tinidazole or clarithromycin, as well as to antibiotic drugs of the macrolide group.

Method of administration and dosage

Pilobact is taken orally, preferably during meals or after meals. Tablets and capsules must be swallowed whole without crushing or chewing.

A single dose of Pilobact is:

Omeprazole - 1 capsule;
Clarithromycin - 1 tablet
Tinidazole - 1 tablet.

The frequency of taking the drug is 2 times a day (in the morning and evening).

The duration of the treatment course is 7 days.

Side effects

Digestive system: dry mouth, flatulence, dysbiosis, constipation or diarrhea, vomiting, metallic taste in the mouth, stomatitis, nausea, abdominal pain, taste disturbances, decreased appetite, transient increase in the activity of liver enzymes in plasma, liver functional disorders, hepatitis (including jaundice), encephalopathy with a history of liver disease; rarely - pseudomembranous enterocolitis;
Central nervous system: tinnitus, ataxia, headache, agitation, dizziness, increased fatigue, drowsiness, weakness, insomnia, depression, paresthesia, confusion, epileptic reactions, hallucinations, disorientation, peripheral neuropathy, depersonalization, fear, convulsions, nightmarish dreams, psychosis;
Musculoskeletal system: myalgia, muscle weakness, arthralgia;
Hematopoietic system: thrombocytopenic purpura, leukopenia, thrombocytopenia, neutropenia, anemia;
Skin: itching; rarely - skin rash; very rarely - exudative erythema multiforme, photosensitization, alopecia;
Allergic reactions: anaphylactic shock, angioedema, urticaria, bronchospasm;
Others: fever, increased sweating, tachycardia, blurred vision, interstitial nephritis, peripheral edema, gynecomastia.

special instructions

Before starting the treatment course, it is necessary to exclude the malignant process (masking the symptoms can make it difficult to make the correct diagnosis).

Caution must be observed when combined with drugs metabolized by the liver. When combined with warfarin or other indirect anticoagulants, it is necessary to control the prothrombin time.

If there is a history of heart disease, concomitant use with cisapride, terfenadine, astemizole is not recommended.

Tinidazole may cause dark urine staining.

During therapy, care must be taken when driving vehicles and performing other potentially hazardous types of work that require a high concentration of attention and quick psychomotor reactions.

Drug interactions

With the combined use of the drugs included in the kit with some drugs / substances, the following effects may be observed:

Theophylline (with clarithromycin): increasing its concentration;
Zidovudine (with clarithromycin): decrease in its absorption (a break between doses of at least 4 hours is required);
Lincomycin, clindamycin (with clarithromycin): development of cross-resistance;
Terfenadine (with clarithromycin): an increase in its concentration and, as a result, a prolongation of the QT interval;
Indirect anticoagulants (with clarithromycin): potentiation of their action;
Carbamazepine, cyclosporine, phenytoin, disopyramide, lovastatin, valproate, cisapride, pimozide, astemizole, digoxin (with clarithromycin): their level may increase;
Phenytoin, diazepam, warfarin (with omeprazole): likely to slow down their elimination;
Ketoconazole, ampicillin and iron salts (with omeprazole): affects their absorption;
Indirect anticoagulants, ethanol (with tinidazole): their action is enhanced (disulfiram-like reactions can be observed);
Phenobarbital (with tinidazole): the metabolism of tinidazole is accelerated.

Omeprazole enhances the inhibitory effect on the hematopoietic system of other drugs.

The simultaneous use of tinidazole with ethionamide is not recommended.

Analogs

There is no information on analogues of Pilobact.

Terms and conditions of storage

Store in a dry place out of reach of children at temperatures up to 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Pilobact: prices in online pharmacies

Drug name

Price

Pharmacy

Pilobact tablets and capsules set 42 pcs.

737 RUB

Buy

Pilobact AM tablets and capsules set 56 pcs.

RUB 900

Buy

Reviews Pilobact AM

RUB 900

Buy

Pilobact AM tablets and capsules combination set. 56 pcs.

1082 RUB

Buy

Pilobakt combined set n42 (6 pcsх7 blist)

1207 RUB

Buy

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!