Thrombin
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Thrombin is a local hemostatic drug.
Release form and composition
The dosage form of Thrombin is a lyophilisate for preparing a solution for external and local use: a loose mass of white or slightly pinkish color (in 10 ml ampoules, 10 ampoules in a cardboard box complete with an ampoule knife).
Active ingredient in 1 ampoule: thrombin - 125 IU (international units).
Indications for use
- surgical interventions on parenchymal organs (spleen, liver, kidneys, lungs, etc.);
- nose, gingival and other capillary bleeding, especially with Werlhof's disease, hypoplastic / aplastic anemia, hemophilia.
Thrombin is also used to study the blood coagulation system in laboratory practice.
Contraindications
- bleeding from large vessels;
- individual intolerance to the components of the drug.
Method of administration and dosage
Thrombin is for local and external use only.
The contents of the ampoule must first be dissolved in 10 ml of 0.9% sodium chloride solution. The resulting solution can be opalescent, transparent. The presence of suspended solids in it is not a contraindication for use.
To stop bleeding (parenchymal or superficial) with a Thrombin solution, it is necessary to soak a sterile hemostatic sponge, which is then applied to the bleeding wound. The sponge soaked in the solution can be left on the wound as it will dissolve later.
In the absence of a sponge, it is possible to use a sterile gauze swab, after stopping the bleeding, it is removed.
Side effects
- secondary infection;
- allergic reactions.
special instructions
Thrombin is not used to stop bleeding from large vessels.
Intramuscular / intravenous administration of the solution is unacceptable, as it can lead to widespread vascular thrombosis with a possible fatal outcome.
To avoid damage to the formed blood clots, remove the tampon soaked in the drug with caution.
Drug interactions
No information provided.
Analogs
Thrombin analogs are: NovoSeven, Tannin, Vilate, Zhelplastan, Alginatol, Ivisel, TachoKomb, Polyhemostat, Hemostatic sponge.
Terms and conditions of storage
Store in a place protected from light and moisture at a temperature of 2-10 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
