Sustilak
Sustilak: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Sustilak
ATX code: M01AX05
Active ingredient: glucosamine (glucosamine)
Producer: Medrik Limited (MEDREICH, Ltd) (India)
Description and photo updated: 20.11.2018
Prices in pharmacies: from 999 rubles.
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Sustilac is a drug that affects metabolic processes in cartilage tissue, stimulates the biosynthesis of proteoglycans and tissue regeneration.
Release form and composition
Sustilac is produced in the form of modified release tablets, film-coated: oval, shell and core - from white to almost white (15 pcs. In blisters, 4 packs in a cardboard box).
1 tablet contains:
- active substance: glucosamine hydrochloride - 1.5 g;
- auxiliary ingredients: microcrystalline cellulose, hypromellose K100M and K200M, calcium hydrogen phosphate, povidone K90, colloidal silicon dioxide, stearic acid;
- shell: macrogol-6000, hypromellose E-5, white opadry (macrogol, titanium dioxide, hypromellose).
Pharmacological properties
Pharmacodynamics
The active ingredient of Sustilak - glucosamine - prevents the destruction of cartilage, stimulates the regeneration of cartilage tissue, has an anti-inflammatory and analgesic effect, and normalizes the production of intra-articular fluid. This effectiveness improves joint mobility and reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).
Pharmacokinetics
- absorption and distribution: after oral administration, glucosamine is absorbed quickly and completely in the gastrointestinal tract (GIT); due to the prolonged form, continuous release of the active component of the drug and its uniform absorption are ensured; bioavailability is 25-26%, the highest concentrations are found in the kidneys, liver and cartilage tissue;
- metabolism and excretion: glucosamine is metabolized by first pass elimination (effect of the first passage through the liver) to urea, carbon dioxide and water; excreted mainly by the kidneys.
Indications for use
Sustilac is recommended for the treatment of osteoarthritis of the peripheral joints and spine.
Contraindications
Absolute:
- severe renal failure;
- the period of pregnancy and breastfeeding (lactation);
- children and adolescents under 18 years of age;
- hypersensitivity to glucosamine and other components of the drug.
Relative (the drug is prescribed with caution):
- bronchial asthma;
- diabetes;
- intolerance to seafood (shellfish, shrimp).
Instructions for the use of Sustilak: method and dosage
Sustilac is intended for oral administration. The tablets should be swallowed whole with water.
Recommended dosage regimen: 1 pc. once a day for 6-12 weeks. The course of therapy, if necessary and on the recommendation of a doctor, can be repeated after a two-month break.
A stable clinically significant therapeutic effect is achieved due to the use of the drug for at least six months.
Side effects
Sustilac is well tolerated, in some cases, there may be side effects such as gastrointestinal dysfunction (flatulence, constipation / diarrhea, epigastric pain, nausea) and / or skin hypersensitivity reactions (pruritus, urticaria).
Overdose
Overdose data have not been reported.
If necessary, gastric lavage and symptomatic treatment should be performed.
special instructions
Patients with seafood intolerances are at increased risk of allergic reactions.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Sustilak does not affect the speed of psychomotor reactions and the ability to concentrate.
Application during pregnancy and lactation
The drug is contraindicated for use during pregnancy and during breastfeeding.
Pediatric use
In pediatric practice, the use of the drug for the treatment of children and adolescents under 18 years of age is contraindicated due to the lack of data on the effectiveness and safety of therapy.
With impaired renal function
For patients with severe renal impairment, the use of Sustilac is contraindicated.
Drug interactions
Sustilac potentiates the absorption of tetracyclines, reduces the effectiveness of semi-synthetic penicillins and chloramphenicol.
Allowed the joint intake of glucosamine with glucocorticosteroids, paracetamol, NSAIDs. Combined use with NSAIDs enhances their anti-inflammatory and analgesic effects.
Analogs
Sustilak's analogs are: Artrakam, Glucosamine, Glucosamine sulfate 750, DONA, Sustagard, Chondroxide, Elbona, etc.
Terms and conditions of storage
Store at temperatures up to 25 ° C in a dry place protected from light. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Sustilak
Many patients prefer the drug in the treatment of osteoarthritis, because, according to reviews, Sustilac gives a stable result after just a few weeks of administration, practically does not cause side effects, does not irritate the stomach and esophagus, is convenient to use (taking once a day), and one package enough for a course of treatment.
In addition, the cost of the drug per treatment course is lower than many analogues.
The price of Sustilak in pharmacies
The approximate price of Sustilak (for 60 pieces in a package) is 1300 rubles.
Sustilak: prices in online pharmacies
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Drug name Price Pharmacy |
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Sustilak 1500 mg modified release film-coated tablets 60 pcs. 999 RUB Buy |
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Sustilac tablets p.p. with mod. release 1500mg 60 pcs. 1140 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
