Sulfacil sodium
Sulfacil sodium: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. The price of sodium in pharmacies
Latin name: Sulfacyl-sodium
ATX code: S01AB04
Active ingredient: sulfacetamide (sulfacetamide)
Manufacturer: Update PFC (Russia), Slavyanskaya pharmacy (Russia)
Description and photo update: 2018-21-11
Prices in pharmacies: from 13 rubles.
Buy
Sodium sulfacil is an antimicrobial agent used in ophthalmology.
Release form and composition
Sodium sulfacyl dosage form - eye drops 20%: transparent colorless or slightly colored liquid (1; 1.5 or 2 ml each in a dropper tube with a valve, 2 tubes in a cardboard box; 5 and 10 ml each in a dropper tube with a screw neck or dropper bottles, in a cardboard box 1 tube / dropper bottle).
Composition of 1 ml of the preparation:
- active substance: sulfacetamide - 0.2 mg;
- auxiliary components: purified water, sodium hydroxide (1M sodium hydroxide solution), sodium disulfite (sodium pyrosulfite).
Pharmacological properties
Pharmacodynamics
The active ingredient of the drug - sulfacetamide - is a substance from the sulfonamide group with antimicrobial bacteriostatic effect. The mechanism of its action is explained by the inhibition of dihydropteroate synthetase, competitive antagonism with para-aminobenzoic acid, as well as the ability to disrupt the synthesis of tetrahydrofolic acid, which is necessary for the synthesis of pyrimidines and purines.
Sodium sulfacyl is active against gram-negative and gram-positive cocci, Actinomyces israelii, Bacillus anthracis, Chlamydia spp., Corynebacterium diphtheriae, Clostridium perfringens, Escherichia coli, Yersinia pestis, Vibrio cholerae, Shigopella spp.
Pharmacokinetics
After instillation, maximum concentrations are reached within 30 minutes and are approximately: 3 mg / ml in the cornea, 0.5 mg / ml in the moisture of the anterior chamber, 0.1 mg / ml in the iris. A small amount (no more than 0.5 mg / ml) remains in the tissues of the eyeball for 3-4 hours. In case of damage to the corneal epithelium, the penetration of the drug increases.
Indications for use
According to the instructions, sodium sulfacil is used as part of the complex therapy of the following diseases:
- purulent corneal ulcer;
- blepharitis and conjunctivitis in children and adults;
- blenorrhea in newborns (treatment and prevention);
- chlamydial and gonorrheal eye diseases in adults.
Contraindications
Sulfacil sodium eye drops are contraindicated in the presence of increased sensitivity to their components.
Instructions for the use of sodium sulfacil: method and dosage
The drug is used topically by instilling it into the conjunctival sac of the affected eye.
Recommended dosage:
- conjunctivitis in adults and children: on the first day, 1-2 drops every hour, in the next 3-4 days the number of instillations is reduced to 5-6 per day;
- blepharitis in children and adults: at the beginning of treatment - 1-2 drops up to 8 times a day, as the condition improves, the number of instillations is reduced to 3-4 per day. The course of treatment is 3-5 days;
- purulent corneal ulcer: 1–2 drops 5–6 times a day for 5–7 days;
- chlamydial and gonorrheal eye diseases in adults: 1-2 drops up to 6 times a day for 4-6 weeks. If there is a positive trend, each subsequent week the number of instillations is gradually reduced;
- prevention of blenorrhea in newborns: 2 drops into the conjunctival sac of each eye immediately after birth, then 2 drops at intervals of 2 hours during the day;
- treatment of blennorrhea: 2 drops every 1-2 hours during the first day, then every 3 hours. The course of treatment is 2 weeks.
Side effects
After the instillation of the drug, the following undesirable reactions may occur: burning, itching, pain in the eyes, lacrimation, transient blurred vision.
In some cases, allergic reactions are possible.
Overdose
No information available.
special instructions
Possible hypersensitivity to sulfacetamide in patients with hypersensitivity to carbonic anhydrase inhibitors, sulfonylureas, thiazide diuretics or furosemide.
Influence on the ability to drive vehicles and complex mechanisms
Patients in whom the clarity of visual perception decreases after instillation of sodium sulfacil eye drops should refrain from driving vehicles and performing potentially hazardous types of work until visual function is restored.
Application during pregnancy and lactation
Due to the lack of sufficient experience in sodium sulfacyl therapy during pregnancy and lactation, the use of the drug is possible strictly according to the doctor's prescription, if the expected benefit is higher than the possible risks.
Drug interactions
Sulfacetamide is incompatible with silver salts.
The bacteriostatic effect of the drug can be reduced by tetracaine and procaine.
Analogs
Analogues of sodium sulfacil are: sodium sulfacil-DIA, sodium sulfacil-Vial, sulfacetamide, sodium sulfacil-SOLOpharm, sodium sulfacyl-MEZ.
Terms and conditions of storage
Store out of the reach of children, protected from light, at a temperature of 2-15 ° C.
Shelf life - 2 years, after the first opening of the bottle - 14 days.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Sulfacil sodium
According to numerous reviews, Sulfacil sodium is an effective antimicrobial drug used to treat eye diseases. The advantage is its rapid action (a significant improvement in the condition is noted after 1-3 days), the disadvantage is unpleasant reactions after instillation (for example, burning and itching), but they quickly pass.
Price for Sulfacil sodium in pharmacies
Approximate prices for sodium sulfacil: 40 rubles. for 2 tubes of 2 ml, 50 rubles. for 1 tube of 10 ml.
Sodium sulfacil: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Sodium sulfacil bufus 20% eye drops 1.5 ml 2 pcs. RUB 13 Buy |
|
Sodium sulfacil 20% eye drops 2 ml 2 pcs. RUB 13 Buy |
|
Sodium sulfacil 20% eye drops 1 ml 2 pcs. RUB 15 Buy |
|
Sodium sulfacil 20% eye drops 10 ml 1 pc. RUB 25 Buy |
|
Sodium sulfacil 20% eye drops 5 ml 1 pc. RUB 27 Buy |
|
Sodium sulfacil 20% eye drops 10 ml 1 pc. RUB 30 Buy |
|
Sulfacil sodium 20% eye drops 1.5 ml 2 pcs. RUB 36 Buy |
|
Sodium sulfacil 20% eye drops 5 ml 1 pc. RUB 37 Buy |
|
Sodium sulfacil 20% eye drops 5 ml 1 pc. RUB 38 Buy |
|
Sodium sulfacil 20% eye drops 2 ml 2 pcs. RUB 45 Buy |
|
Sodium sulfacil eye drops 20% 1.5ml 2 pcs. RUB 58 Buy |
|
Sodium sulfacil 20% eye drops 5 ml 1 pc. RUB 78 Buy |
| See all offers from pharmacies |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
