Solpadein - Instructions For Use, Indications, Doses

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Solpadein - Instructions For Use, Indications, Doses
Solpadein - Instructions For Use, Indications, Doses

Video: Solpadein - Instructions For Use, Indications, Doses

Video: Solpadein - Instructions For Use, Indications, Doses
Video: Солпадеин таблетки - показания (видео инструкция) описание - Парацетамол, Кофеин, Кодеина фосфат 2024, November
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Solpadein

Instructions for use:

  1. 1. Release form and composition
  2. 2. Indications for use
  3. 3. Contraindications
  4. 4. Method of application and dosage
  5. 5. Side effects
  6. 6. Special instructions
  7. 7. Drug interactions
  8. 8. Terms and conditions of storage

Prices in online pharmacies:

from 79 rub.

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Soluble tablets Solpadein
Soluble tablets Solpadein

Solpadein is a combined drug of analgesic, antipyretic and antitussive action.

Release form and composition

Solpadein is available in the following forms:

  • tablets: elongated, capsule-shaped, white, on one side there is a red "Solpadeine" marking (5 or 6 pieces in blisters, in a plastic box-cover 1 or 2 blisters; 8 pieces in blisters, in a plastic box-cover or in a cardboard box 1 blister; 12 pieces in blisters, in a cardboard box 1 blister);
  • soluble tablets: flat, white, beveled, with a risk on one side, the other side is smooth (2 pieces in strips, in a cardboard box 2, 4, 6, 12 or 30 strips);
  • capsules: size no. 0, hard gelatinous, opaque, with a white body and a red or reddish-brown cap, both parts of the capsule bear the inscription "Solpadeine" in black; content - amorphous white powder with crystalline inclusions (6 pieces in blisters, in a cardboard box 1 or 2 blisters; 12 pieces in blisters, in a cardboard box 1 blister).

Composition of 1 tablet:

  • active ingredients: paracetamol - 500 mg, caffeine - 30 mg, codeine phosphate hemihydrate - 8 mg;
  • auxiliary components: potassium sorbate, soluble starch, purified talc, magnesium stearate, corn starch, hydroxypropyl methylcellulose, povidone, stearic acid, ethanol 95%, microcrystalline cellulose, carmazin, demineralized water.

Composition of 1 soluble tablet:

  • active ingredients: paracetamol - 500 mg, caffeine - 30 mg, codeine phosphate hemihydrate - 8 mg;
  • auxiliary components: sodium saccharin, polyvidone, sorbitol, dimethicone, sodium carbonate anhydrous, sodium lauryl sulfate, sodium bicarbonate, citric acid anhydrous.

Composition of 1 capsule:

  • active ingredients: paracetamol - 500 mg, caffeine - 30 mg, codeine phosphate hemihydrate - 8 mg;
  • auxiliary components: corn starch, magnesium stearate;
  • capsule shell: gelatin, titanium dioxide, dye iron oxide red;
  • lettering ink: shellac, isopropanol, butanol, propylene glycol, black iron oxide dye, purified water.

Indications for use

Solpadein is prescribed to adult patients and adolescents over 12 years of age with pain syndrome, including the following pain:

  • neuralgia;
  • toothache;
  • a sore throat;
  • pain with sinusitis;
  • migraine;
  • headache;
  • muscle and joint pain;
  • pain with sprains and radiculitis;
  • menstrual pain.

The drug is also used for infectious and inflammatory, including colds, diseases and flu to reduce fever (in adolescents over 12 years old and adults).

Contraindications

Absolute:

  • organic diseases of the cardiovascular system (atherosclerosis, acute myocardial infarction);
  • arterial hypertension;
  • oppression of hematopoiesis (neutropenia, agranulocytosis);
  • frequent ventricular premature beats, paroxysmal tachycardia;
  • blood diseases (anemia, thrombocytopenia);
  • hypocoagulation;
  • bronchial asthma, respiratory failure, diseases with increased sputum secretion;
  • increased intracranial pressure;
  • anxiety disorders (panic disorder, fear of open space);
  • epilepsy;
  • condition after TBI (traumatic brain injury);
  • sleep disorders;
  • severe hepatic and / or renal impairment;
  • alcohol intoxication;
  • children under 12 years old;
  • During pregnancy and breastfeeding;
  • prenatal period;
  • concomitant use of other medicines containing paracetamol or codeine;
  • hypersensitivity to the main or auxiliary ingredients of the drug.

Relative (Solpadein is used with caution):

  • viral hepatitis;
  • glaucoma;
  • alcoholism;
  • alcoholic liver damage;
  • liver or kidney disease;
  • bowel dysfunction (including constipation);
  • increased excitability;
  • tendency to seizures;
  • deficiency of glucose-6-phosphate dehydrogenase;
  • benign hyperbilirubinemia (Dubin-Johnson syndrome, Gilbert's syndrome);
  • simultaneous administration of antiemetic, lipid-lowering drugs, tricyclic antidepressants, indirect anticoagulants, hypnotics and sedatives, ethanol, monoamine oxidase inhibitors, tranquilizers from the phenothiazine group;
  • elderly age.

Method of administration and dosage

Solpadein is taken orally after meals. Tablets and capsules are swallowed whole with water; soluble tablets preliminarily dissolved in 1 / 2 cups of water.

Teenagers over 16 years old and adults are prescribed 1-2 tablets or 2 capsules 3-4 times a day. The interval between doses should be at least 4 hours. Maximum doses: single - 2 tablets or 2 capsules, daily - 8 tablets or 8 capsules.

Children 12-16 years old are prescribed 1 tablet or 1 capsule of Solpadein 3-4 times a day. The interval between doses should be at least 4 hours. Maximum doses: single - 1 tablet or 1 capsule, daily - 4 tablets or 4 capsules.

It is not recommended to exceed the indicated doses.

Solpadein is taken for no more than 3 days as a means to reduce elevated body temperature and no more than 5 days as an anesthetic.

Increasing the dose, frequency of administration or duration of use is possible only as directed by the attending physician.

Side effects

When used in recommended doses, Solpadein is generally well tolerated.

In some cases, allergic reactions such as rash, urticaria, bronchospasm or angioedema are possible.

Side effects that paracetamol can cause:

  • hematopoietic system: agranulocytosis, thrombocytopenia, leukopenia, methemoglobinemia, hemolytic anemia;
  • liver and kidneys: impaired hepatic and renal function (with long-term treatment in high doses).

Side effects caffeine can cause:

  • cardiovascular system: arrhythmia, tachycardia, increased blood pressure, palpitations;
  • central nervous system: headache, anxiety, agitation.

Side effects that codeine can cause:

  • cardiovascular system: tachycardia, palpitations;
  • central nervous system: drowsiness, dizziness, sleep disturbance;
  • digestive system: vomiting, nausea, gastralgia, constipation.

special instructions

During the period of taking Solpadein, excessive consumption of coffee and tea is not recommended, as this can lead to sleep disturbances, cardiac arrhythmias, tachycardia and increased agitation.

With long-term treatment in high doses, it is necessary to control the peripheral blood picture.

While taking the drug, you should refrain from taking alcoholic beverages.

Solpadein contains codeine, therefore, with prolonged uncontrolled use, drug dependence and addiction may develop (weakening of the analgesic effect).

In the event of side effects from the digestive system, rash, itching, ulcers on the oral mucosa, hematomas, difficulty breathing, swelling of the face, lips, tongue, increased bleeding, the drug should be immediately canceled and consult your doctor.

While taking Solpadein, patients should be especially careful when driving and performing other potentially dangerous work.

Drug interactions

With the simultaneous use of Solpadein with rifampicin, salicylamide, barbiturates, antiepileptic drugs and other inducers of microsomal oxidation, toxic metabolites of paracetamol are formed, which negatively affect liver function.

When taken together with ethanol, the risk of hepatotoxic effects increases; with metoclopramide - the absorption of paracetamol is accelerated; with ergotamine - the absorption of ergotamine is enhanced; with inhibitors of microsomal oxidation (including cimetidine) - the risk of paracetamol hepatotoxicity decreases; with chloramphenicol - the half-life of chloramphenicol increases by 5 times.

With repeated administration, Solpadein may enhance the effect of indirect anticoagulants and increase the risk of bleeding.

Codeine is able to potentiate the effect of drugs that depress the central nervous system (including alcohol), but since its amount in the drug is insignificant, this effect is insignificant.

Terms and conditions of storage

Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Shelf life: tablets and capsules - 5 years; soluble tablets - 4 years.

Solpadein: prices in online pharmacies

Drug name

Price

Pharmacy

Solpadein Fast 65 mg + 500 mg film-coated tablets 12 pcs.

79 RUB

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Solpadein Fast Solpadeine Fast pain reliever, tablets, 12 pcs.

117 RUB

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Solpadein Fast 65 mg + 500 mg soluble tablets 8 pcs.

122 RUB

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Solpadein Fast 65 mg + 500 mg film-coated tablets 24 pcs.

131 r

Buy

Solpadein Fast 65 mg + 500 mg soluble tablets 12 pcs.

183 r

Buy

Reviews Solpadein Fast

183 r

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Solpadein Fast Solpadeine Fast anesthetic, soluble tablets, 12 pcs.

RUB 218

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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